Term
|
Definition
Hydroxychloroquine
Nonbiologic drug
Dose range 200-400 mg
1-2 doses per day
PO |
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Term
|
Definition
Sulfasalazine
Dose range: 2,000 - 4,000 mg
2-3 doses per day
PO
Nonbiologic drug |
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Term
|
Definition
Methotrexate
Dose range: 7.5-25 mg
once weekly
PO, IM, SC, IV
Nonbiologic drug |
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Term
|
Definition
Gold sodium thiomalate
DOse range: 25-50mg
every 2-4 weeks
IM
Nonbiologic drug |
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Term
|
Definition
Auranofin
Dose range:3-6 mg
1-2 doses a day
PO
Nonbiologic drug |
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Term
|
Definition
Azathioprine
Dose range: 50-150mg
1-2 doses a day
PO, IV
Nonbiologic drug |
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Term
|
Definition
Minocycline
Dose range: 100-200 mg
2 doses a day
PO
Nonbiologic drug |
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Term
|
Definition
Leflunomide
Dose range: 10-20 mg
1-2 doses per day
PO
Nonbiologic drug |
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|
Term
|
Definition
Etanercept
25 mg
twice weekly or 50 mg once weekly
SC
Biologic |
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Term
|
Definition
Infliximab
3 mg/kg
Weeks 0,2, and 6 then every 8 weeks
IV
Biologic |
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Term
|
Definition
Anakinra
100 mg
1 dose per day
SC
Biologic |
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Term
|
Definition
Adalimumab
40 mg
Every other week
SC
Biologic |
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|
Term
|
Definition
Abatacept
<60kg = 500mg
60-100 kg = 750 mg
>100kg=1000mg
Weeks 0,2,4 then q 4 weeks
IV
Biologic |
|
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Term
|
Definition
Rituximab
1,000 mg
Every 2 weeks for two doses
IV
Biologic |
|
|
Term
|
Definition
Tocilizumab
4mg/kg; may be increased to 8mg/kg on the basis of clinical response
every 4 weeks
iv
Biologic |
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Term
|
Definition
Diclofenac
150-200 mg/d
3-4 times a day
PO, opthalmic, topical gel
Acetic Acid |
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|
Term
|
Definition
Diclofenac
100-200 mg/d
1-2 times a day
PO
Acetic acid |
|
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Term
|
Definition
Etodolac
600-1,200 mg/d
2-4 times a day
PO
Acetic acid |
|
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Term
|
Definition
Etodolac
400-1,000 mg/d
1 time a day
PO
Acetic acid |
|
|
Term
|
Definition
Indomethacin
100-200mg/d
203 times a day
PO IV Suppository
Acetic acid |
|
|
Term
|
Definition
Indomethacin
75-150mg/d
1-2 times a day
PO
Acetic acid |
|
|
Term
|
Definition
Nabumeton
1,000-2,000 mg/d
1-2 times a day
PO
Acetic acid |
|
|
Term
|
Definition
Tolmetin
600-1,800 mg/d
3 times a day
PO
Acetic acid |
|
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Term
|
Definition
Sulindac
300-400mg/d
2 times a day
PO
Acetic acid |
|
|
Term
|
Definition
Fenoprofen
900-3200mg/d
3-4 x a day
PO
Propionic Acid |
|
|
Term
|
Definition
Flurbiprofen
200-300mg/d
2--4 times a day
PO
Propionic Acid |
|
|
Term
|
Definition
Ibuprofen
1,200-3,300 mg/d
3-4 x a day
PO
Propionic Acid |
|
|
Term
|
Definition
Ketoprofen
150-300mg/d
3-4 x a day
PO
Propionic Acid |
|
|
Term
|
Definition
Ketoprofen SR
100-200mg/d
1 x a day
PO
Propionic Acid |
|
|
Term
|
Definition
Naproxen
500-1500mg/d
2-3x a day
PO
Propionic Acid |
|
|
Term
|
Definition
Oxaprozin
1,200-1,800 mg/d
1 x a day
PO |
|
|
Term
|
Definition
Meclofenamate
200-400 mg/d
3-4 x a day
PO
Fenamates |
|
|
Term
|
Definition
meloxicam
7.5-15mg/d
1x a day
PO
Oxicam |
|
|
Term
|
Definition
Piroxicam
10-20mg/d
1-2 x a day
PO
Oxicam |
|
|
Term
|
Definition
Celecoxib
200-400mg/d
1-2 x a day
PO
COX-2 selective |
|
|
Term
|
Definition
Colchicine
Anti-inflammatory
1.2 mg PO followed by 0.6 mg 1 hr latter
Max dose is 1.8 mg over 1 hour
Drug may be used for chronic supprisve therapy; dose must be adjusted for renal insuffeciency
PO |
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Term
|
Definition
Probenecid
Uriosuric agent
250-500mg BID
Avoid salicylates; take with plenty of water
PO |
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Term
|
Definition
Sulfinpyrazone
Uricosuric agent
50-200mg BID
Avoid salicylates; take with plenty of water
PO |
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Term
|
Definition
Allopurinol
Xanthine oxidase inhibitor
100-300 mg qd or divided dose
Drug may cause rash; reduce dosage in renal failure. |
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Term
|
Definition
Febuxostat
Xanthine oxidase inhibitor
40 mg daily; if uric acid is not less than 6 mg/dl increase to 80 mg daily
drug may be used in mild renal impairment |
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Term
|
Definition
Indomethacin
NSAID
50 mg TID
Drug may cause fluid retention, GI bleeding
PO, IV, Suppository |
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Term
|
Definition
Belimumab
monoclonal antibody that inhibits binding of Human B Lymphocyte stimulator protein to tis receptor on B cells. Useful in SLE |
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|
Term
| What treats acute gouty arthritis: |
|
Definition
| Colchicine, NSAIDS or glucocorticoids |
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|
Term
| What is used to prevent gouty attacks: |
|
Definition
| Uricosuric agents, xanthine oxidase inhibitors and uricase agents |
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