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Radiation Dose- Response Relationship
N/A
17
Physics
Professional
04/18/2013

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Term
the measured effect increases in direct proportion to the radiation dose
Definition
linear
Term
the measured effect increases disproportionally to the dose
Definition
nonlinear
Term
the measured effect does not occur at all below a certain dose level, but suddenly appears at that dose level
Definition
threshold
Term
the measured effect occurs at all dose levels including zero dose
Definition
nonthreshold
Term
two applications of dose-response relationships
Definition
design therapeutic treatment routines for patients with cancer
provide info on the effects of low dose irradiation
Term
early or late
high dose or low dose
deterministic or stochastic
Definition
human response to radiation
Term
usually following high dose exposure and early response
ex radiation induced skin burns
Definition
deterministic radiation
Term
usually follows low radiation exposure, appears as late radiation response
ex cancer
Definition
stochastic
Term
acute radiation syndrome
epilation
erythema
desquamation
Definition
deterministic effects
Term
leukemia
cancers
Definition
stochastic effects
Term
every radiation dose response has two characteristics
Definition
linear or nonlinear
AND
threshold or nonthreshold
Term
the response is ___ proportional to the dose
Definition
directly
Term
when any dose is expected to produce a response
Definition
linear, nonthreshold
Term
when a dose requires a threshold greater than zero to produce a response
Definition
linear, threshold
Term
the dose-response relationship is represented by a curve and does not increase in direct proportion to the dose
Definition
nonlinear dose response relationships
Term
when any dose is expected to produce a nonproportional response
Definition
nonlinear, non threshold
Term
when a dose requires a threhold greater than zero to produce a response, becoming increasingly effective per increment, until it reaches the inflection point
Definition
nonlinear, threshold
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