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Quiz 13 - Chapter 31
Defense System
32
Science
10th Grade
02/05/2008

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Term
Pathogens
Definition

Disease causing organisms (virus, bacteria, fungi, protozoa, worms)

Term
Infectious Disease
Definition
Disease caused by PATHOGENS; not from genetic inheritance (hemophilia)
Term
Joseph Lister (1865)
Definition
Scottish physician: 1st to use Carbolic Acid in antiseptic surgery
Term
Louis Pasteur (1864)
Definition
French chemist; disproved Spont. Gen. & established Germ Theory Disease
Term
Robert Koch (1880s)
Definition
German microbiologist; postulates used to prove cause of specific disease
Term
Barriers (1st Defense)
Definition
External defense (skin, enzymes, lysozyme, acids, mucociliated epithelium)
Term
Paul Ehrlich (1908)
Definition
German microbiologist; Father of Chemotherapy; "magic bullet" for syphilis
Term
2nd Defense (nonspecific)
Definition
Internal defense (macrophages, complement, inflammation response)
Term
Inflammation Response
Definition
Non-specific local internal response (swelling, redness, heat, and pain).
Term
Complement
Definition
Non-specific blood protein stimulated by antibodies; poke holes in microbe
Term
Interferon
Definition
Non-specific protein secreted by virus-infected cell (blocks reproduction)
Term
Targeted Defense (3rd line)
Definition
Immune Response (Cell Mediated + Humoral) against specific pathogen
Term
Immunity
Definition

Resistance to a pathogen that causes specific disease (vaccine or prior expos...

Term
Antigen
Definition
Protein (usually surface) that stimulates an IMMUNE response
Term
Antibodies
Definition
Specific blood proteins produced by PLASMA cells (humoral immunity)
Term
B-cells
Definition
Lymphocytes involved with HUMORAL immunity (antibodies in blood)
Term
T-cells
Definition

Lymphocytes most involved with CELL MEDIATED immunity

Term
Plasma Cell
Definition
Activated B-lymphocyte; produces many antibodies specific to antigen sti...
Term
Humoral Immunity
Definition
Immunity originated from B-cells (ie. Antibodies in blood)
Term
Cell-Mediated Immunity
Definition

Immunity originated from T-cells (lymphocytic attack)

Term
T-helper cells
Definition
Lymphocytes that activate both humoral & cell mediated immune response
Term
Macrophage
Definition
Non-specific phagocyte; presents pathogenic antigens on surface (B/T cells)
Term
Memory Cells
Definition
Activated B-cells; set aside for quick SECONDARY response to pathogen
Term
Second Immune Response
Definition
Quicker/stronger response w/ 2nd exposure to pathogen (no symptoms)
Term
Dr. Jonas Salk
Definition
Microbiologist; developed 1st polio vaccine (chem., disabled)
Term

Vaccine

Definition
Gives ARTIFICIAL, but active immunity; disabled pathogen stimulates IS...
Term
Active Immunity
Definition
Body produces antibodies, natural or acquired (vaccine); long-term immunity
Term

Passive Immunity

Definition
Body RECEIVES antibodies from another source; short-term immunity
Term
Allergy
Definition
Over sensitivity to a non-harmful allergen
Term
Histamine
Definition
Hormone released by MAST cells; causes VASODILATION.
Term
Autoimmune Response
Definition

Immune system turns against SELF (Lupus, Rheumatoid Arthritis, MS)

Term
AIDS
Definition
Fatal viral disease from HIV; destroys body's T-helper cells & immunity
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