Term
Presentation of ACETYSALICYLIC ACID |
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Definition
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Term
Pharmacology of ACETYSALICYLIC ACID |
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Definition
Assists by inhibiting the synthesis of prostaglandins and thromboxane in the circulating platelets. The antithrombotic action forms the basis of preventing platelets from aggregating to exposed collagen fibres at sites of vascular injury. |
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Term
| Metabolism of ACETYSALICYLIC ACID |
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Definition
Converted to Salicyclic acid in many tissues but primarily in the GI mucosa and liver and excreted by the kidneys. |
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Term
Indications for ACETYSALICYLIC ACID |
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Definition
| Suspected AMI or myocardial ischaemia. |
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Term
Contra-Indications of ACETYSALICYLIC ACID |
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Definition
- KSAR to aspirin or NSAIDS
- Bleeding Disorders
- Current GI Bleeding or peptic ulcer
- Children under 12 years
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Term
Precautions for ACETYSALICYLIC ACID |
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Definition
- Possible Aortic Aneurysm or other condition requiring surgery
- Pregnancy
- Hx of peptic ulcers or GI bleeding
- Concomitant anti-coagulant therapy (not clopidogrel)
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Term
Side Effects of ACETYSALICYLIC ACID |
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Definition
- Epigastric pain/discomfort
- Nausea/vomiting
- Gastritis
- GI Bleeding Tinnitus
- Bronchoconstriction in some asthmatics
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Term
Route of Administration for ACETYSALICYLIC ACID |
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Definition
- To be chewed and followed by a glass of water
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Term
Drug Effect ACETYSALICYLIC ACID |
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Definition
- 10 minutes - depending on stomach contents
- Anti-platelet action lasting for several days
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Term
| DONWAY - Goal of Treatment |
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Definition
Reduce, align and immobilize long bone fractures.
To reduce muscle spasm, pain and reduce further damage. |
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Term
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Definition
| Long bone fractures of the leg. |
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Term
| DONWAY - Contra-Indications |
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Definition
Bi-lateral fractures.
Caution must be taken for knee dislocations and multiple fractures of the one leg. |
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Term
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Definition
Offer pain relief.
Be honest about pain involved in procedure.
Align fracture gently and carefully.
Always release air pressure after locking splints. |
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