| Term 
 | Definition 
 
        | Ventilation w/o perfusion.  If this exceeds 0.6 as a fraction of total ventilation mechanical ventilation may be required. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Area of lung where gas exchange cannot occur, if this exceeds 5% by much then this may become clinically significant |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | anatomic dead space (150ml) + alveolar dead space |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | acute hypoxemia with PaO2:FiO2 < 300mm Hg |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | acute hypoxemia w/PaO2 < 200mm Hg |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | systemic inflammatory response syndrome, ARDS is a component |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | 20% - 30% of total lung capacity.  complicating factor that some lung is not uniformly injured, some portion is compliant |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | volume/pressure.  less compliant lungs have high airway pressures reducing compliance |  | 
        |  | 
        
        | Term 
 
        | tidal volume strategy with mechanical ventilation in ARDS |  | Definition 
 
        | low tidal volume of 6ml/kg |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | rapid onset, short acting (in healthy patients, longer in ICU).  Vd increases with renal impairment.  also cyp 3A4 metabolism, inhibitors increase duration |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | long half-life, active metabolites, cheapest of the 'pams' |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | aseptic techniques necessary; most expensive; rapid onset, short duration; pancreatitis, high calorie; decreases intracranial pressure; |  | 
        |  |