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Pulmonary Diseases
Pathophysiology I UMDNJ DPT 2012
167
Medical
Undergraduate 1
09/25/2009

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Cards

Term
Divisions of the Respiratory System
Definition
1) Upper Airway
2) Lower Airway
3) Terminal Alveoli
Term
Parts of Upper Airway
Definition
Nasal cavities
Sinuses
Pharynx
Tonsils
Larynx
Term
Parts of Lower Airway
Definition
Conducting Airway:
Trachea
Bronchi
Non-respiratory Bronchioles)
Term
Parts of the Terminal Alveoli
Definition
Respiratory Bronchioles
Alveolar Ducts
Alveolar Sacs
Term
Generations of Airways
Definition
There are 26 generations.

The first 16 are purely conducting

Next are transitional airways

24th gen: Final Respiratory zone
Term
Classification of Pulmonary Disease
Definition
* Acute or Chronic

* Obstructive or Restrictive - tend to be chronic / incurable

* Infectious or Non-infectious - more often acute
Term
Signs and Symptoms of Pulmonary Disease
Definition
Cough
Dyspnea
Orthopnea
Pleuritic Pain
Cyanosis
Clubbing
Altered Breathing Patterns
Tachypnea
Abnormal chest wall shape
Abnormal sputum
Using accessory mm. of breathing
Nasal Flaring
Hemoptysis
DOE - Dyspnea on exertion
SOB
Term
Common Sites for referred Pulmonary Pain
Definition
Chest
Ribs
UT
Shoulder-may radiate along medial arm
T/S
Term
Characteristics of Pulmonary Disease Pain
Definition
May mimic MS pain in referral sites

Increases with Inspiratory Movements
Term
Pleural layer and Pain
Definition
Parietal Pleura is very sensitive to pain

Visceral Pleura is not sensitive to pain
Term
Conditions Caused by Pulmonary Disease
Definition
Hypoxemia
Pulmonary Edema
Term
Definition of Hypoxemia
Definition
Deficient oxygenation of arterial blood

Can lead to hypoxia
Term
Hypoxia
Definition
Diminished availability of O2 to body tissues
Term
Causes of Hypoxemia
Definition
Respiratory alterations
V/Q mismatch
Decreased O2 Content
Hypoventilation
Alveolocapillary diffusion abnormality
Pulmonary Shunting
Term
Signs and symptoms of Hypoxemia for PaO2 80-100
Definition

 

 

 

 normal

Term
Signs and symptoms of Hypoxemia for PaO2 60-80
Definition

PaO2 Signs and Symptoms 60-80

Tachycardia DOE possibly-respiratory distress

Term
Signs and symptoms of Hypoxemia for PaO2 50-60
Definition

malaise

light

headedness

nausea

vertigo

impaired judgement

Term
Signs and symptoms of Hypoxemia for PaO2 35-50
Definition

 

marked confusion

 

cardiac dysrrhythmias

 

labored respiration

Term
Signs and symptoms of Hypoxemia for PaO2 25-35
Definition

 

cardiac arrest

decreased renal blood flow

decreased urine output

lactic acidosis

lethargy

LOC

Term
Signs and symptoms of Hypoxemia for PaO2 <25
Definition

 

 

 decreased VE

Term
Pulmonary Edema
*Emergency condition*
Definition
Definition
Accumulation of fluid in the tissues and air spaces of the lungs

Most commonly caused by heart disease, LVF, but also a complication of pulmonary disease
Term
Pneumonia

Definition
Definition
Inflammation affecting the parenchyma of the lungs

Can be:

Lobar p.
Bronchopneumonia
Term
Pneumonia

Etiology
Definition
Bacterial infection
Viral infection - can be more serous
Inhalation or aspiration of particulate etc.
Term
Pneumonia

Risk Factors
Definition
Bronchitis
Smoking
immunodeficiency
intubation
COPD
Chronic Renal Failure
Chemotherapy
Bed Rest
Impaired cough reflex
Dysphagia
i
Term
Pneumonia

Signs
Definition
Pleuritic chest pain
Productive Cough with rust or green sputum
Dyspnea
Tachypnea
Fatigue
Fever
Generalized aches
Term
Pneumonia

Dx
Definition
Sputum Cultures
Gram Stain
Chest Films
Lung Sounds
Chest Percussion
Urine test
Term
Pneumonia

Tx
Definition
Antibiotic Therapy
Chest PT
Rest
Fluids
Term
Pneumonia

Vaccination
Definition
Recommended for

Over 65
Chronic disorders of the lungs
Heart
Liver
Kidney
and HIV or poorly controlled DM
Term
Pneumocystis Carinii Pneumonia (PCP)
Definition
Parasitic Infection-AIDS
First indicator of AIDS in 60% of cases
Also seen in:
Transplants
Chemo for lymphoma or leukemia
Steroid Therapy in Malnutrition
Term
Pneumocystis Carinii Pneumonia (PCP)

Signs
Definition
Impaired Gas Exchange
Fever
Dyspnea
Weight Loss
Tachypnea
Term
Pneumocystis Carinii Pneumonia (PCP)

Interventions
Definition
Universal Precautions
Breathing Exercises
Energy Conservation
Term
TB

Definition
Definition
Infectious, inflammatory systemic disease that affects the lungs.

May disseminate to involve lymph nodes and other organs
Term
TB

Etiology part 1
Definition

Cause: Inhalation of infected airborne particles

Infection with mycobacterium tuberculosis characterized by granulomas*, caseous necrosis, and cavity formation


(A granuloma is a small area of inflammation in tissue due to injury, such as from an infection. Granulomas most often occur in the lungs but can occur in other parts of the body as well. They typically cause no signs or symptoms and are found incidentally on a chest X-ray done for some other reason. Although granulomas are noncancerous (benign), they may resemble cancer on an X-ray.-Source www.mayoclinic.com)

Term
TB

Etiology Part 2
Definition
primary infection involves middle or lower lung area and spreads to bronchopulmonary lymph nodes and then travels to the bloodstream
Term
TB

Risk Factors
Definition
Elderly
Poor health
<5 years old
Close quarters
inadequate ventilation
HIV
Term
TB

Signs
Definition
Appear late-usually after one year
productive cough
wt loss
fever
night sweats
fatigue
anorexia
pulmonary infections
lung atelectasis - collapse of a lung segment
Term
TB

Dx
Definition
skin test (Mantoux)
chest xray
culture of sputum
bronchoscopy
Term
TB

Rx
Definition
combination drugs-rifampin, isoniazid
etc.
prevent transmission, need to be
taken for 6-9 months
Term
Acute Bronchitis

Definition and Cause
Definition
Def: Inflammation of trachea and bronchi-Lasts for about 1-3 weeks

Cause: Chemicals, viral infections
Term
Acute Bronchitis

Signs
Definition
cough
chest pain
constitutional sxs

Can lead to pneumonia
Term
COPD
Definition
Refers to several disorders including:

Obstructive Bronchitis
Emphysema
Asthma
Term
COPD

Dx
Definition
blood gas analysis
sputum culture
skin testing
xray
PFTs= Pulmonary Function Test
Term
COPD

Treatment Goal
Definition
Improve PaO2
Decrease CO2 retention
Prevent resp infection
Term
COPD

Rx
Definition
Pharm management:
bronchodilators
mucolytics
steroids
antibiotics
mast cell stabilizers
oxygen
vaccination against flu
Pulmonary hygiene
Bullectomy-Removal of non-funct. alveoli
Chest PT
Term
Chronic Obstructive Bronchitis

Def and Cause
Definition
Productive cough lasting 3 mos. For two
consecutive years, dec FEV1/FVC

Causative agent: smoking
Term
Chronic Obstructive Bronchitis

Signs
Definition
Cough with mucous
Cyanosis
Prolonged expiration
Recurrent infection
SOB
Hypoxemia
Retention of C02
Accessory breathing muscles
hypertrophy of mucous producing cells
air trapping
*forced expiration tends to produce
collapse of tissue
Term
Emphysema
Definition
Obstructive Lung disease (3 types) that causes destruction of airways due to changes in lung tissue rather than mucous
Term
Emphysema

Etiology
Definition
Smoking
Term
Emphysema

Signs
Definition
dyspnea
tachypnea with prolonged expiration
wasting appearance
leaning forward with arms
braced on knees to assist breathing
Term
Asthma

Definition
Definition
*Inflammation of airways causing
bronchospasm with SOB and wheezing

*Reversible obstructive lung disease caused by increased reaction of the A/W to various stimuli
Term
Asthma

Disease process
Definition
Release of inflammatory mediators (leukotrienes) produces:

bronchial smooth muscle spasm
vascular congestion
edema
increased mucus production
impaired mucociliary function
--eosinophil infiltration
Airway spasm
trapping air
ventilation/perfusion mismatch
hypoxemia
Term
Asthma

Signs
Definition
first-sensation of chest constriction
inspiratory/expiratory wheezing
non-productive coughing
tachycardia
tachypnea
later cough becomes productive with nasal flaring and cyanosis of lips
Term
Asthma

Dx
Definition
PFT
ABGs- arterial blood gas

Note: Asthma occurs in families
Term
Asthma

Rx
Definition
bronchodilators
steroids
leukotriene inhibitors
Term
Asthma

Types
Definition
Exercise Induced
(bronchodilators 20-30 min. prior to ex)

Intrinsic - nonallergic; adult onset; secondary to chronic infection

Extrinsic- Allergic Asthma
Term
Bronchiectasis
(bron-kee-ek-ta-sis)

Definition
Definition
A progressive form of obstructive lung disease
characterized by irreversible destruction and dilation
of A/Ws associated with chronic bacterial infections
Term
Hemoptysis

Definition
Definition
Coughing up blood or bloody sputum
Term
Bronchiectasis

Disease process
Definition
Chronic dilation of bronchi and bronchioles with wet secretions that plug airways and cause more purulent
mucous causing bronchospasm.

Destruction of bronchial walls occur with fibrosis that further obstructs lumen
Term
Bronchiectasis

Signs
Definition
persistent coughing
increased amounts of sputum (gray and smelly)
anemia
fever
may have hemoptysis
weight loss
weakness
Term
Bronchiectasis

Rx
Definition
chest PT

Bronchodilators

Antibiotics

Poor prognosis. Rare condition.
Term
Bronchiolitis

Definition
Definition
Severe inflammation of the lower
airways caused by viral infection.
Term
Bronchiolitis Disease process
Definition

bronchiolar mucosa swells and fills with mucus.

 

Hyperinflation and obstruction occur Most Common in Children<2 yrs (preemies)

 

Associated with RSV*

 

*(Respiratory syncytial virus)

Term
Bronchiolitis

Signs
Definition
Cough

Respiratory Distress

Cyanosis
Term
Sleep Apnea

Definition
Definition
Episodes of cessation of breathing occurring at transition from NREM to REM with repeated awakenings

Defined as more than five cessations for at least 10 sec each per hour
Term
Sleep Apnea

Types
Definition
Central Apnea-related to CNS

Obstructive Apnea-related to obesity etc.
Term
Sleep Apnea

Risk Factors
Definition
narrowed upper A/Ws
obesity
adenoid uvula and tonsil hypertrophy smoking
Term
Sleep Apnea

Signs
Definition
snoring
breath cessation
thrashing mov’t of extremities
daytime sleepiness
headaches
personality changes
Term
Sleep Apnea

Rx
Definition
Weight Loss

CPAP
Term
Restrictive Lung Diseases
Definition
(Some type of restriction) limits lung expansion – can not get air
into the lungs
Term
Restrictive Lung Diseases

Signs and Symptoms
Definition
Chronic hyperventilation
Initially DOE
Later, dyspnea @ rest
Respiratory muscle fatigue leading to decreased alveolar ventilation and increased CO2 retention
hypoxemia
Term
Restrictive Lung Diseases

Causes
Definition
Weakness from Neuromuscular Disease

Interstitial Lung Diseases
Term
Pulmonary Fibrosis

Def
Definition
Excessive fibrous tissue in lung that replaces normal tissue due to chronic inflammation
Also known as interstitial lung disease (See causes of Restrictive Lung Diseases)
Term
Pulmonary Fibrosis

Causes
Definition
healing scar tissue after TB
systemic sclerosis
ARDS = Adult respiratory distress syndrome
Inhalation of toxic substances
~2/3 of cases are idiopathic
Term
Pulmonary Fibrosis

Dx and Prognosis
Definition
RX - corticosteriods
Poor prognosis
Term
Systemic Sclerosis and Lung Disease

Def
Definition
Scleroderma-autoimmune disease of
connective tissue with excessive collagen deposition in skin and internal organs
(Skin and organs slowly become thicker and less flexible)
Term
Systemic Sclerosis and Lung Disease

Disease progression
Definition
skin changes generally precede visceral
alterations
unpredictable course – ½ develop
interstitial lung disease (AKA Pulmonary Fibrosis)
Term
Systemic Sclerosis and Lung Disease

Rx
Definition
Low Dose Prednisone
Term
Chest Wall Disease
Definition
A variety of conditions including:
*Superficial wounds of the chest wall
*Tension Pneumothorax
*Flail Chest
Term
Chest Wall Disease

Pneumothorax
Definition
Occurs when air leaks into the space between your lungs and chest wall, creating pressure against the lung.

The lung can partially or completely collapse.
Term
Chest Wall Disease

Flail Chest
Definition
2 or more fxs of adjacent ribs
on the same side or of the sterum, may cause paradoxical mov’t of chest
Term
Chest Wall Disease

Rx
Definition
pain meds
mechanical ventilation may be needed
Term
Pneumonconiosis

Def
Definition
Group of disorders caused by lung damage resulting from inhalation of industrial substances (iron,coal dust, asbestos, silica, talc, beryllium). Exposure over 10 yrs
Term
Pneumonconiosis

Disease Process
Definition
Smaller dust particles are more
dangerous-reach smaller airways.
Particles are indestructible and produce
an inflammatory process that results in
excess fibrosis
Term
Pneumonconiosis

Signs and symptoms
Definition
Progressive dyspnea-1st DOE then DO rest chest pain
chronic cough
expectoration of mucus
Term
Hypersensitivity Pneumonitits

Def
Definition
Extrinsic allergic alveolitis resulting from
– environmental exposure
– mold, sugar cane, fungal spores etc.
Term
Hypersensitivity Pneumonitits

Disease Process
Definition
immune complex-mediated and Tcell-mediated
hypersensitivity.
Symptoms begin abruptly with exposure -Occur again with repeat exposure
Term
Hypersensitivity Pneumonitits

Signs and Symptoms
Definition
dyspnea
fever
chills
nonproductive cough

Mild fibrous can occur
Term
Smoke Inhalation

Def
Definition
mucosal injury via hot gases (Burns)

asphyxia as 02 is consumed by fire

Burns in upper airway produces
edema and obstruction

-possibility of cascade
-poor prognosis
Term
CF

Def
Definition
Inherited disease of exocrine glands. Affects hepatic,digestive, male reproductive system and respiratory
system
Term
CF

Disease Process 1
Definition
Altered chloride and sodium channels
Dehydration with increased viscosity of secretions from mucous glands
-lungs
-pancreas
-intestines
-sweat glands
-pancreatic enzyme insufficiency
-high salt content in sweat
Term
CF

Disease Process 2-Pulmonary Aspect
Definition
Progresses from mucus plugging of small airways to bronchitis, then bronchiectasis, pneumonia and
fibrosis; later involves all bronchi
Term
CF

Disease Process 3-Pancreatic aspect
Definition
Thick secretion block ducts preventing
enzymes from reaching the -duodenumresults in fatty stools
Term
CF

Signs and Symptoms #1 -Pancreatic/digestive aspect
Definition
meconium ileus at birth
prolapse of the rectum
risk of impaction
Term
CF

Signs and Symptoms #2 -Pulmonary Aspect
Definition
chronic cough and sputum production
increased risk of infection
reduced oxygen CO2 exchange
acidosis
Term
CF

Dx
Definition
sweat test (salt content)
stool fat measurements
pancreatic elastase-1
Term
CF

Rx
Definition
antibiotics
drugs to thin secretions
adequate hydration
nutritional support
pancreatic enzymes
mucolytics
CPT
exercise
Term
Atelectasis

Def
Definition
Lung collapse
Term
Atelectasis

Types
Definition
Obstructive-absorptive Type
Compressive Type
Term
Atelectasis

Obstructive-absorptive type
Definition
collapse resulting from removal of air
from obstructed or hypoventilated
alveoli
Term
Atelectasis

Compressive Type
Definition
collapse due to air, blood or
fluid filling the pleural space
Term
Atelectasis

Signs
Definition
dyspnea
tachypnea
cyanosis
fever
decreased BP
shock
Term
Atelectasis

Dx
Definition
via xray
Term
Atelectasis

Rx
Definition
remove cause
suctioning or bronchoscopy
prevention (especially in
postsurgical patients)
breathing exercises
percussion/vibration
Term
Pulmonary Edema

Def
Definition
Fluid in the lungs which leak into interstitial tissue and in alveoli
Term
Pulmonary Edema

Causative Factors
Definition
Results from left ventricular failure
Acute HBP
mitral valve disease
Noncardiac causes-liver disorders and kidney disorders in which there is sodium and water retention
Specifically from fluid overload, increased capillary permeability, decreased albumin, and increased lymphatic obstruction
Term
Pulmonary Edema

Signs
Definition
peristant cough
dyspnea
diaphoresis (sweating)
intolerance to ex.
As fluid increases, these signs become more pronounced.

cough may produce a pink
frothy sputum, wheezing occurs and
resp rate increases
Term
Pulmonary Edema

Dx
Definition
clinical presentation and c-xray
Term
Pulmonary Edema

Rx
Definition
meds, ventilation
Term
ARDS

Def
Definition
Adult Respiratory Distress Syndrome

Result of injury to the lung by a variety of disorders – a collection of symptoms
Term
ARDS

Disease Process Part 1
Definition
Damage to capillary endothelial cells
and alveolar epithelial cells which
inactivates surfactant and allows fluids, proteins, and cells to leak from capillary
Term
ARDS

Disease Process Part 2
Definition
Leads to pulmonary edema and
alveolar collapse, impairment of lung
compliance
Term
ARDS

Signs
Definition
initially increased resp rate then
dyspnea, hyperventilation, cyanosis
Term
ARDS

Dx
Definition
exam of ABGs (arterial blood gasses)
and microbiologic cultures
xrays
Term
ARDS

Rx
Definition
treat underlying condition, ventilation
Term
ARDS

Prognosis
Definition
unpredictable
pulmonary fibrosis may result
mortality rate is 50-70%
if accompanied with sepsis-90%

-may seem fine in 1st 24hrs then crash
Term
Sarcoidosis

Def
Definition
Systemic disease of unknown cause
Granulomas throughout body
Lungs and lymph nodes commonly affected
Term
Sarcoidosis

Signs
Definition
dyspnea, dry cough, fever, skin lesions
Term
Sarcoidosis

Dx
Definition
chest xray
Term
Sarcoidosis

Rx
Definition
steroids
Term
Lung Cancer
Definition
Most frequent cause of CA death in the US
Classified as small cell lung CA (SCLC)
or NSCLC
Term
Lung Cancer

Four Major Types
Definition
SCLS:
1) Oat Cell
NSCLC:
2) Squamous Cell Carcinoma
3) Adenocarcinoma
4) Large Cell Carcinoma
Term
Lung Cancer

Frequency of each type
Definition
SCLC: 20%

NSCLC: 80%
Term
Lung CA

Small Cell (Oat Cell)
Definition
cells become so dense that there is almost no cytoplasm
-compressed into an ovoid mass. Located centrally near hilum.
Rapid growth rate with early mets. Secretes ACTH.
Term
Lung CA

Small Cell (Oat Cell) Symptoms
Definition
Early stage symptoms do not differ from
pulmonary sx associated with smoking
Term
Lung CA

Small Cell (Oat Cell) Rx
Definition
chemo + radiation
Term
Lung CA

NSCLC - Squamous Cell
Definition
Growths arise in central potion of lung
near hilum, projecting into bronchi, have a central cavity,
stays local longer (slower mets)
Term
Lung CA

Adenocarcinoma
Definition
mod growth rate
growths arise in periphery of lung
early mets
Term
Lung CA

Large Cell Carcinoma
Definition
peripheral pulmonary tumors that
cause sharp and significant pleural pain
early mets
poorest prognosis
Term
Lung CA

Symptoms
Definition
Sx also depend on location:
central tumors obstruct airflow
peripheral tumors only produce pain
when pleura is affected, may limit lung
expansion
Term
Lung CA

Pancoast's Tumors
Definition
Tumors of apex of lung
invade brachial plexus (shoulder pain)
Term
Lung CA

Dx
Definition
via xray
CT
lung imaging fluorescence endoscope
bronchoscopy
Term
Lung CA

Rx
Definition
surgery with lymph node resection
radiation, and chemo.

Surgery choice in NSCLC and chemo.
Radiation in SCLC with chemo
Term
Lung CA

Mets
Definition
spread by extension, lymphatics and
through vascular system; often to brain, liver, and bone
(long bones and spine esp T-spine
producing chest shoulder, arm or back pain)
Term
Lung CA

Paraneoplastic Syndromes
Definition
effects of malignancy felt remotely-hypercalcemia
osteoarthropathies
DVT
Term
Pulmonary Embolism (PE)

Def
Definition
Lodging of blood clot in a pulmonary Artery with subsequent obstruction of blood supply to lung parenchyma
Term
Pulmonary Embolism (PE)

Risk Factors
Definition
blood stasis 2nd to immobilization
endothelial injury 2nd to surgery
trauma
hypercoagulable states (BCP)
DVT (VTE)
obesity
smoking
HTN
malignancy
fxs of hip or femur
Term
Pulmonary Embolism (PE)

Signs
Definition
Signs depend on the size of the PE-
homans sign
pleuritic chest pain
persistent cough
hemoptysis
diaphoresis
fever
tachypnea
sudden death
Term
Pulmonary Embolism (PE)

Prevention
Definition
Prevention is key given high mortality

– LMW Heparin-prevent clot extension
thrombolytic therapy to lyse emboli,
greenfield filter in vena cava
Term
Pulmonary Embolism (PE)

Implications for PT
Definition
consider the possibility of PE following hip and knee surgery

avoid the following:
restrictive clothing
crossing legs
prolonged sitting
pillow under knees in supine
extreme flexion at hips
Term
Pulmonary Embolism (PE)

If DVT or PE has been Dx'd
Definition
no massage to legs
watch for any evidence of bleeding
Term
Pulmonary Embolism (PE)

Prevention
Definition
bed exercises for the LEs,
compression stockings, early ambulation,
hydration
Term
Pulmonary Hypertension

Def
Definition
HBP in pulmonary arteries. 5-10 mm Hg
above normal (15-18 mm Hg)
Term
Pulmonary Hypertension

Types
Definition
Primary Pulmonary Hypertension

Secondary Pulmonary Hypertension
Term
Pulmonary Hypertension

Primary-Cause
Definition
narrowing of pulmonary arterioles
by hypertrophy of smooth muscles
Term
Pulmonary Hypertension

Secondary-Cause
Definition
increases in volume or pressure of blood entering the pulmonary arteries
Term
Pulmonary Hypertension

Sx (both)
Definition
fatigue
tachypnea
cyanosis
dyspnea
Term
Pulmonary Hypertension

Rx (both)
Definition
oxygen for hypoxemia
digitalis
diuretics
Term
Pulmonary Hypertension

Prognosis (both)
Definition
Poor w/o heart-lung transplant
Term
Cor Pulmonale

Def
Definition
Also called pulmonary heart disease
Enlargement of right ventricle secondary to pulmonary hypertension
Term
Cor Pulmonale

Signs
Definition
Related to pulmonary disorder
(cough,exertional dyspnea, wheezing). Exercise induced peripheral cyanosis distended neck veins
peripheral edema
Low cardiac output
causes pallor
sweating
hypotension
impaired consciousness
Term
Cor Pulmonale

Rx
Definition
reduce workload of right ventricle
Term
Pleurisy

Def
Definition
Inflammation of the pleura caused by infection, injury or tumor
Term
Pleurisy

Signs and Symptoms
Definition
Sharp sticking chest pain worse on inspiration, coughing or with movement, also cough, fever, and rapid shallow breathing may be present.
Pleural rub
Term
Pleurisy

Types
Definition
Diaphragmatic
Wet pleurisy
Dry Pleurisy
Term
Pleurisy

Diaphragmatic P.
Definition
refers pain to neck,
supraclavicular fossa, and upper trap
Term
Pleurisy

Wet P.
Definition
less likely to cause pain because the
fluid content increases
Term
Pleurisy

Dry P.
Definition
causes pain due to the the layers
rubbing against each other
Term
Pleural Effusions
Definition
Collection of fluid in the pleural space (space btw. 2 pleural layers)

Any condition that interferes with the drainage or secretion of this fluid will lead to pleural effusion
Term
Pleural Effusions

Etiology
Definition
– Transudates
Abnormalities of the hydrostatic or osmotic
pressure
CHF, Cirrhosis with ascities
– Exudates
Increased permeability or trauma
Infection, PE, surgical trauma
Term
Pneumothorax
Definition
Accumulation of air or gas in pleural cavity caused by defect in visceral pleura, results in collapsed lung
Term
Pneumothorax

Signs
Definition
SOB, hypoxia, mediastinal shift
toward the unaffected side compressing
the opposite lung
Term
Pneumothorax

Spontaneous
Definition
"bleb"
collection of air within layers of viscera pleura
"bulla"
air-filled, thin-walled space within lung (destruction of alveoli)
Term
Pulmonary Pain Patterns

Tracheobronchial pain
Definition
referred to sites in the neck and ant chest at the same levels as the points of irritation in the air passages
Term
Pulmonary Pain Patterns

Bronchi
Definition
innervated by vagus but finer bronchi and lung parenchyma are free of pain innervation
Term
Pulmonary Pain Patterns

Diaphragmatic Pleura
Definition
receives dual
pain inervation through phrenic and
intercostal nerves-sharp pain to upper
traps and shoulder
Term
Pulmonary Pain Patterns

Pleuropulmonary disorders
Definition
substernal or chest over involved lung fields, may radiate to neck, upper traps, shoulder, or upper abdomen. Thoracic back pain occurs with
irritation of the posterior parietal pleura.
May be sharp or stabbing
Term
Pulmonary Pain Patterns

Lung CA
Definition
Ant chest with referral to scapula, upper back, shoulder, may radiate
along the medial aspect of arm. Sharp
pleuritic pain
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