Term
What are the major expectorants?
Which is most effective
What are the side effects of Iodide exectorants?
Which is the most common? |
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Definition
Expectorants
Iodide
Guaifenesin- Most common
Hydration- Most effective
Iodide Adverse effects
Acneiform skin Eruptions
Erethema of face and chest,
Hypothyroid
Painful Salivary Swellings |
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Term
What are the major mucolytics?
What is their mechanismm?
How do you prevent the side effects? |
|
Definition
Acetylcysteine
Dornase
Mech: cleave disulfide bonds in mucus
Prevent Bronchospasm: Simpathomimetic or Acetyl Cysteine with Isoproterenol |
|
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Term
What are the major decongestants,
Which is Long Acting?
What is the adverse effect of the long acting? |
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Definition
Short
Phenyl Ephrine-Rebound Hyperemia
Long
Pseudoephedrine |
|
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Term
Mast cell stabilizing Drugs?
What is their mechanism?
When must they be given? |
|
Definition
Cromolyn, Neocromil
Mech: Block Cl preventing vesicle release
Use: must be prophyllactic |
|
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Term
| Asthma drugs that must be administered prophyllatic? |
|
Definition
Mast Stabilizing
Anti-cholinergics
Leukotriene Antagonists |
|
|
Term
Centrally Acting Antitussives?
What is the major adverse effect? |
|
Definition
Dextromethorphan, Codiene
Adverse: Respiratory depression |
|
|
Term
What are the peripherally active Anti-tussives?
|
|
Definition
Demulcants
Local anesthetics
Humidifying Aerosols
Expectorants |
|
|
Term
What is the mechanism of Methylxanthines?
What is the side effects of Methylxanthines? |
|
Definition
Mech: Nonselective Phosphodiesterase block decreasing cAMP degradation
Adverse
CNS: Tremor, Nervousness
GI: Acidity, Enzymes
Renal: Diuresis
CV: Chronotrope, Inotrope |
|
|
Term
| Simpathomimetics for Asthma Which are Long term |
|
Definition
Albuterol
Metoproterenol
Terbutaline
Long: Salmeterol, Formeterol |
|
|
Term
| Precaution with Psuedoephrine |
|
Definition
| Conversion to Methamphetimine by drug abusers |
|
|
Term
What are the Antimuscarinics used in asthma? What else are they administered with?
Which is the longest acting? |
|
Definition
Ipratropium, Tiotropium(longest)
With a B2 agonist cover lag |
|
|
Term
Corticosteroids Used in Asthma?
What should be done with administration? |
|
Definition
Beclomethasone, Triamcinolone, Flucticasone, Prednisone
Admin: Rinse with water |
|
|
Term
| Lox pathway Blocking Drugs and Mechanisms |
|
Definition
| Zileuton: 5-Lipoxygenase Inhibitor Zafirlukast: LTD4 Blocker |
|
|
Term
| Treatment Regimens for Asthma |
|
Definition
Mild: SABA
Chronic: ICS or Cromolyn
Severe: ICS and LABA
Severe/Prolonged: OCS |
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