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Pulm-Micro
Respiratory Viruses
50
Microbiology
Graduate
10/03/2010

Additional Microbiology Flashcards

 


 

Cards

Term
Most common Cold viruses
Definition
Rhinovirus, Coronavirus, Reovirus, Parinfluenzae1,2,3,InfluenzaA,B,C, RSV
Term
Most common laryngitis viruses
Definition
Infleunza, Rhinovirus, Adenovirus, Parainfluenza, RSV
Term
Most common Exudative tonsilitis/pharyngitis
Definition
Epstein Barre Virus, Adenovirus
Term
Most common acute lymphnodular pharyngitis
Definition
Enterovirus (coxsackie A10)
Term
Most common Croup viruses
Definition
Parainfluenza(1,3), RSV, Influenza(A,B), Adenovirus, Measules
Term
Most common viral Bronchiolitis Pneumonia
Definition
RSV, Parainfluenza(1,3), Influenza(A,B), Adenovirus, Measules
Term
Most common pneumonia viruses
Definition
RSV, Influenza(A,B), Parainfluenza(1,3), Adenovirus, Measules
Term
Morphology of rhinovirus
Definition
No-enveloped, (+) ssRNA, Best @ 33 degrees
Term
Pathogenesis of Rhinovirus
Definition
Binds ICAM-1 on Host cells
Term
Immunity to Rhinovirus
Definition
sIgA provides immunity
Term
Diagnosis of Rhinovirus
Definition
Viral Isolation
Term
Epidemiology of Rhinovirus
Definition
Fall/Spring, #1 in Adults
Term
Why Rhinovirus only affects URT
Definition
Grows better at lower temperatures
Term
Coronavirus Morphology
Definition
Enveloped, (+) ssRNA
Term
Features of the Coronavirus
Definition
Nestled Genome
Viral-encoded RNA-Dependant RNA Polymerase
Term
Immunity to Coronavirus
Definition
Local immunity for 1-2 years, not systemic
Term
Epidemiology of Coronavirus
Definition
Winter->Spring, #2 in Colds, Adults
Term
Sars Virus Symptoms
Definition
Fever, Diarrhea, Respiratory
Term
What type of virus is SARS
Definition
Coronavirus
Term
Lab diagnosis of Corona virus
Definition
PCR: 2 culture (+) (Nasal, Stool) Elisa for Ab
Term
Treatment for SARS
Definition
None, just support
Term
Adenovirus Morphology
Definition
Non-enveloped dsDNA
Term
General Syndromes of Adenovirus by Serology
Definition
Respiratory:1,2,5,6 GI:3,7,8 Eye:40,41
Term
Epidemiology of Adenovirus
Definition
Winter->Spring, Army, Younger patients
Term
Diagnosis of Adenovirus
Definition
Serology, but shedding occurs for 3 months
Term
Prevention to Adenovirus infection
Definition
Vaccine to 4,7 for Army
Term
Immunity to Adenovirus
Definition
Maternal Ig, Long Lasting Ig
Term
Morphology of Influenza Virus
Definition
Encasulated, (-) ssRNA, Segmented Genome
Neuraminidase- Cleaves Sialis Acid, denuding the ciliated epithelium
Hemaglutinin-(A,B Only) binds Mucoprotein receptor
Term
Classifications of Influenza
Definition
A,B,C by Ribonucleoprotein
Hemaglutinin and Neuraminidase by number
Term
Antigenic changes in Influenza
Definition
Antigenic Shift: Reassortment/
Recombination event that drastically changes the behavior of a virus
Antigenic Drift: Mutation events that slowly change the appearance of a virus
Term
Lifecycle of Influenza
Definition
Nuclear Replication and transcription, ER Enveloping
Term
Pathogenesis of Influenza
Definition
Heagluttinin bind mucoprotein receptor
Neuramidase denudes ciliated cells of respiratory tract
Term
Epidemiology of Influenza
Definition
Winter-> spring
Pandemics: 30-40 yrs
Epidemics: 2-3 for A, 3-6 for B
Term
Presentation of Influenza
Definition
Myalgia, Fever, Respiratory, GI in B
Term
Immunity to Influneza
Definition
Cytotoxic T, IFN, Ab
Term
Complications of Influenza
Definition
Otitus Media, Viral/Bacterial/combo pneumonia, Guilian Barre(Myelitis), Cytokine Storm->Respitory distress, Reye's Syndrome: Encephalopathy, Fatty Liver
Term
Susceptible people to influenza
Definition
<1, elderly, Immunocompromised
Term
Influenza Diagnosis
Definition

Culture

Elisa Ab Detection

Serology (4xs Rise)

Term
Treatment of Influenza
Definition
Amantidine, Rimantidine: Block uncoating
Obseltamivir, Zanamivir: Block Neuramidase
48 HOUR WINDOW
Term
Prevention of Influenza
Definition
Amantidine, Rimantidine Daily for A Vaccines: Killed->50, Healthcare, Childcare, 6-23 months, Pregnant Women Nasal Vaccine: Attenuated (5-50yrs)
Term
Paramyxoviruses
Definition
parainfluenza, RSV, Measules, Mumps
Term
Presentation of Parainfluneza Virus
Definition
Mild URT: HPIV 1-3
Croup: HPIV 1,2
Bronchiolitis: HPIV 3
Term
Immunity to Parainfluenza
Definition
sIgA short lived
No maternal protection
F protein Ab prevents spread
NM Ab neutralizes virus
Term
Treatment/Prevention of Parainfluenza
Definition
Ribavirin No vaccines
Term
Respiratory Synctial Virus Morphology
Definition
Enveloped (-) ssRNA, No Hemagluttinin or Neuraminidase
Term
Epidemiology of RSV
Definition
Children, #1 Nosocomial in PEDS
#1 Bronchitis/Pneumonia
Term
What patients of RSV get croup vs bronchiolitis/pneumonia
Definition
Croup: Older
Bronchiolitis/Pneumonia: Younger
Term
Diagnosis of RSV
Definition
ELISA, Synctial Tracheal Swab
Term
Treatment/ Prevention of RSV
Definition
Ribiviren, Support
RSV-IGIV, Palivizumab Against F: decreases hospitalizations by 50%
Term
What viral infections are more associated with adults?
Definition
Rhinovirus and Coronavirus
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