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PTherapeutics I T3 Smoking Cessation
Smoking
26
Pharmacology
Professional
04/25/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
How much nicotine is inhaled from 1 cigarette?
Definition
1mg
Term
how long does it take for nicotine to reach the brain?
Definition
10-20 sec
Term
What happens to nicotine when it is metabolized?
Definition
70-80% becomes the NONactive metabolite, cotinine
Term
Nicotine stimulates _____release
Definition
Dopamine
Term
Certain drugs may have decreased effects due to the induction of _____ by smoking
Definition
CYP1A2
Term
smokers who use ______ are at risk for serious CV AEs, including_______
Definition
Oral Contraceptives; Stroke, MI, Thromboembolism
Term
What clinical effects does Bupropion SR (Zyban) have on the smoker?
Definition
reduces cravings & symptoms of withdrawal
Term
Patients with seizure disorders, eating disorders or undergoing alcohol/sedative withdrawal should not take ________
Definition
bupropion
Term
Patients should not take Bupropion SR within _____ of taking an MAO-I
Definition
14 days
Term
To avoid seizure risk with Bupropion, do not exceed ______
Definition
300 mg/d
Term
Bupropion dosing:
First three days & remainder.
Definition
days 1-3: 150 mg QAM
Then, 150 mg BID for 12 weeks
Term
Patients (should/should not) continue with bupropion if the have not quit after the regimen is completed.
Definition
should not
Term
What are the clinical effects of Varenicline (chantix)?
Definition
Do not reel benefits of smoking, as well as decreased withdrawal symptoms
Term
Dosing regimen for Chantix?
hint: days 1-3, 3-7, 8-end
Definition
days 1-3: .5mg QD
Days 4-7 .5 mg BID
Days 8-end 1mg BID
Term
Varenicline should be taken with ________
Definition
full glass of water
Term
Varenicline should be discontinued in the event of _____
Definition
swelling of the face and mouth
Term
Patients with _______ should take caution before starting nicotine replacement therapy
Definition
Underlying CV dx
Term
With the exception of the transdermal patch, what is the minimum doses taken per day for every nicotine replacement therapy?
Definition
9
Term
What is the max number of NRT gum pieces a PT may have? Do patients taper up or Taper down?
Definition
nte 25 pieces. Taper down.
Term
With nicotine lozenges, how do PTs know which dosage to take?
Definition
based on time to first cigarette:
if within 30 minutes of waking, 4 mg; if more, 2 mg
Term
How many NRT lozenges may a PT have in a day?
Definition
20
Term
With the gum and lozenge, what sort of time frame should the PT wait as far as consuming food/drink?
Definition
15 minutes before and after
Term
how many weeks is the NRT gum used and how frequently? how long dose it take for each piece of gum?
Definition
6 weeks; every 1-2 hrs. takes about 30 mins
Term
How long should a PT avoid using a spot with the nicotine patch?
Definition
a week
Term
Which NRT product has the fastest absorption?
Definition
nasal spray
Term
What are the 5 R's of increasing motivation?
Definition
Relevance
Risks
Rewards
Roadblocks
Reputation
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