| Term 
 
        | How much nicotine is inhaled from 1 cigarette? |  | Definition 
 | 
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        | Term 
 
        | how long does it take for nicotine to reach the brain? |  | Definition 
 | 
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        | Term 
 
        | What happens to nicotine when it is metabolized? |  | Definition 
 
        | 70-80% becomes the NONactive metabolite, cotinine |  | 
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        | Term 
 
        | Nicotine stimulates _____release |  | Definition 
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        | Term 
 
        | Certain drugs may have decreased effects due to the induction of _____ by smoking |  | Definition 
 | 
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        | Term 
 
        | smokers who use ______ are at risk for serious CV AEs, including_______ |  | Definition 
 
        | Oral Contraceptives; Stroke, MI, Thromboembolism |  | 
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        | Term 
 
        | What clinical effects does Bupropion SR (Zyban) have on the smoker? |  | Definition 
 
        | reduces cravings & symptoms of withdrawal |  | 
        |  | 
        
        | Term 
 
        | Patients with seizure disorders, eating disorders or undergoing alcohol/sedative withdrawal should not take ________ |  | Definition 
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        | Term 
 
        | Patients should not take Bupropion SR within _____ of taking an MAO-I |  | Definition 
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        | Term 
 
        | To avoid seizure risk with Bupropion, do not exceed ______ |  | Definition 
 | 
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        | Term 
 
        | Bupropion dosing: First three days & remainder.
 |  | Definition 
 
        | days 1-3: 150 mg QAM Then, 150 mg BID for 12 weeks
 |  | 
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        | Term 
 
        | Patients (should/should not) continue with bupropion if the have not quit after the regimen is completed. |  | Definition 
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        | Term 
 
        | What are the clinical effects of Varenicline (chantix)? |  | Definition 
 
        | Do not reel benefits of smoking, as well as decreased withdrawal symptoms |  | 
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        | Term 
 
        | Dosing regimen for Chantix? hint: days 1-3, 3-7, 8-end
 |  | Definition 
 
        | days 1-3: .5mg QD Days 4-7 .5 mg BID
 Days 8-end 1mg BID
 |  | 
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        | Term 
 
        | Varenicline should be taken with ________ |  | Definition 
 | 
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        | Term 
 
        | Varenicline should be discontinued in the event of _____ |  | Definition 
 
        | swelling of the face and mouth |  | 
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        | Term 
 
        | Patients with _______ should take caution before starting nicotine replacement therapy |  | Definition 
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        | Term 
 
        | With the exception of the transdermal patch, what is the minimum doses taken per day for every nicotine replacement therapy? |  | Definition 
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        | Term 
 
        | What is the max number of NRT gum pieces a PT may have? Do patients taper up or Taper down? |  | Definition 
 
        | nte 25 pieces. Taper down. |  | 
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        | Term 
 
        | With nicotine lozenges, how do PTs know which dosage to take? |  | Definition 
 
        | based on time to first cigarette: if within 30 minutes of waking, 4 mg; if more, 2 mg
 |  | 
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        | Term 
 
        | How many NRT lozenges may a PT have in a day? |  | Definition 
 | 
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        | Term 
 
        | With the gum and lozenge, what sort of time frame should the PT wait as far as consuming food/drink? |  | Definition 
 
        | 15 minutes before and after |  | 
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        | Term 
 
        | how many weeks is the NRT gum used and how frequently? how long dose it take for each piece of gum? |  | Definition 
 
        | 6 weeks; every 1-2 hrs. takes about 30 mins |  | 
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        | Term 
 
        | How long should a PT avoid using a spot with the nicotine patch? |  | Definition 
 | 
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        | Term 
 
        | Which NRT product has the fastest absorption? |  | Definition 
 | 
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        | Term 
 
        | What are the 5 R's of increasing motivation? |  | Definition 
 
        | Relevance Risks
 Rewards
 Roadblocks
 Reputation
 |  | 
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