Term
| Which drug(s) is/are a cholinesterase inhibitor(s)? |
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Definition
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Term
| Which drug is no longer used due to hepatotoxicity? |
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Definition
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Term
| ________has/have an MoA of specific and reversible inhibition of ACHe |
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Definition
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Term
| ______ is APPROVED for mild to severe Alzheimer's |
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Definition
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Term
| Donepezil is available as ____ dosage form(s) |
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Definition
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Term
| Which drug(s) may be taken with or without food? |
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Definition
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Term
| Which drug is a 2D6 and 3A4 substrate moreso than other drugs? |
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Definition
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Term
| Which drug has the least incidence of GI effects? |
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Definition
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Term
| Which drugs are renally eliminated? |
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Definition
| Donepezil, Rivastigmine, Galantamine, Memantine... so, basically, all of them |
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Term
| Which drug(s) inhibit butyrylcholinesterase and ACHe? |
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Definition
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Term
| Which drug is used in mild to moderate Alzheimers? |
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Definition
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Term
| Rivastigmine is available in _______ dosage form(s) |
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Definition
| capsule, oral solution, patch |
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Term
| Which drug(s) should be taken with food/meals? |
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Definition
| Rivastigmine, Galantamine |
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Term
| Which drug(s) is/are selective, competitive, reversible ACHe inhibitor(s) that enhance(s) ACh action on nicotinic receptors? |
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Definition
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Term
| Galantamine is available as ______ dosage forms |
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Definition
| oral solution, tab, ER cap |
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Term
| Which drug is the only NMDA receptor antagonist |
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Definition
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Term
| Which drug is USED in moderate to severe alzheimer's? |
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Definition
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Term
| Memantine is used both in monotherapy and can be combined with _______ |
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Definition
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Term
| Which drug, in the event of severe renal impairment (10-29 ml/min), must have its dose adjusted? |
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Definition
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Term
| What are the antipsychotics used in Alzheimers? |
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Definition
ZHOQueR:
Ziprasidone, Haloperidol, Olanzapine, Quetiapine, Risperidone |
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Term
| Which drug(s) has/have a BBW for dementia? What is the BBW for? |
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Definition
| The antipsychotics; warns for increased risk of mortality if used in dementia |
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Term
| Which antidepressants are used for alzheimers? |
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Definition
SSRIs most efficacious & include:
CiFPS; Citalopram, fluoxetine, paroxetine and Sertraline |
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Term
| Which antidepressant has the most anticholinergic SEs? |
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Definition
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Term
| Which drug(s) may worsen cognition, cause disinhibition and increase fall risk? |
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Definition
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Term
| BZDs are (less/equally/more) effective compared to antipsychotics for anxiety, agitation and aggression. |
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Definition
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Term
| which BZDs are used in alzheimers? |
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Definition
| Lorazepam and Oxazepam (LO) |
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