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| used to order C-II controlled substances |
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| Controlled substance act of 1970 identified five classes C-I through C-5, requires DEA registration for pharmacies etc |
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| Combat Methamphetamine Epidemic Act |
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| Set daily and monthly restrictions on pseudofed |
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| Prohibited interstate commerce in adulterated or misbranded food, govt pre-approval of drugs required |
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| Requires tax and licensing from manufacturers, pharmacists, and importers and physicians who provide narcs |
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| 1927 Food, Drug and insecticide administration |
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| 1938 Food Drug and Cosmetic Act (FDC) |
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| requires new drugs to be shown safe before marketing after 107 ppl poisoned |
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| 1950 Alberty Food Products v. US |
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| Court of Appeals ruled purpose for which a drug is to be used must be included on label |
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| 1951 Durham-Humphrey Amendment |
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| Requires RX-only on label |
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| 1962 Kefauver-Harris Amendment |
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| Requires proof of both safety and effectiveness before marketing drug |
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| 1966 Fair Packaging and Labeling Act |
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| Requires honest and informative labelling (whatever the hell that means) |
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| 1970 Poison Prevention Packaging ACt |
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| Child-proof packaging on all drugs unless pt request |
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| 1976 Medical Device Amendment |
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| Requires pre-market approval for safety and effectiveness of life-sustaining and life-supporting medical devices |
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| Incentives for creating drugs for rare diseases |
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| 1984 Drug Price Competition and Patent Term Restoration Act (Hatch-Waxman) |
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| allows patent term extensions, and earlier generic introductions |
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| 1987 Prescription Drug Marketing ACt |
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| requires state licensing of drug wholesalers and requires drugs to be sold by them only |
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| requires pharmacists to offer counseling to medicaid patients regarding medications |
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| 1996 Health Insurance Portability and Accountability Act |
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| HIPPA--privacy rules, cannot share private pt information |
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| 1990 Anabolic Steroid Control Act |
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| anti-steroids for teenagers |
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| when blood is forced out of the heart--high pressure |
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| when blood pressure is lower--relaxation phase |
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for atrial fibrillation
generic: warfarin |
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atrial fibrilation
generic: metoprolol |
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congestive heart failure
generic: carvedilol |
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congestive heart failure
generic: enalapril |
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coronary artery disease
generic: amlodipine |
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Definition
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coronary artery disease
genric: clopidogrel |
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hypertension
generic: valsartan |
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hypertension
generic: furosemide |
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diabetes insipidus (excessive thirst, diluted pee, bad kidney regulation)
generic: vasopressin |
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diabetes mellitus (insulin-related diabetes)
generic: insulin lispro |
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diabetes mellitus
regular insulin is the generic |
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diabetes mellitus
generic: tolbutamide |
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hyperthyroidism
generic is methimazole |
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Definition
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hypoaldosteronism (low aldosterone, which regulates sodium potassium and water levels)
brand is florinef |
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hypothyroidism
brand is levoxyl or synthroid |
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constipation
brand: colace |
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| diphenoxylate with atropine |
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GERD (gastrointestinal reflux disease)
prilosec |
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nausea vomiting
brand is compazine |
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acne vulgaris
brand: retin-a |
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atopic dermatitis
brand: elidel |
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atopic dermatitis
brand: protopic |
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herpes labialis (cold sores)
brand: abreva |
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impetigo (contagious skin infection pus blisters)
brand: keflex |
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impetigo
chlamydia (std)
myringitis (inflammation of the tympannic membrane)
brand: zithromax |
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psoriasis (white scaley flaking)
brand: dovonex |
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hemophilia
brand: kogenate-fs |
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lymphoma, multiple myeloma
brand: cytoxan |
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non-hodgkin's lymphoma
brand: rituxan |
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| fibromyalgia (muslce pain) |
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gout (defective metabolism of uric acid causes painful arthritis)
brand: indocin |
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multiple sclerosis
brand: copaxone |
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muscle spasms
brand: valium |
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rheumatoid arthritis (immune system attacks cartilage)
brand: mobic |
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spasticity (unusual tightness in muscles)
brand: lioresal |
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tendinitis
brand: naprosyn |
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hsv encephalitis (viral brain inflammation)
brand: zovirax |
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parkinson's disease
brand: requip
binds dopamine receptors |
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parkinson's disease
brand: sinemet
inhibits conversion of precursors to dopamine in the PNS, so there will be more precursors moving to produce dopamine in the CNS |
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arthritis/spondylitis (spine fuses together 0_0)
brand: enbrel |
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osteoporosis
brand: actonel |
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osteoporosis
brand: fosamax |
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paget's disease (enlarged misshapen bones)
brand: didronel |
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rheumatoid arthritis (immune system arthritis)
brand: mobic |
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breast cancer
brand: ellence |
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dysmenorrea (painful cramps during menstruation)
brand: cataflam |
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endometriosis (cells from the womb grow elsewhere in the body, making it hard to get pregnant etc)
brand: synarel |
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ovulation induction (fertility drugs that make you have multiple eggs)
brand: clomid |
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benign prostatic hyperplasia (enlargement of the prostate)
brand: flomax |
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benign prostatic hyperplasia (enlargement of the prostate)
brand: proscar |
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genital hsv infection
brand: valtrex |
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prostate cancer
brand: casodex |
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allergic rhinitis (allergies in your nose)
brand: zyrtec |
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chronic obstructive pulmonary disease
brand:combivent |
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Definition
| albuterol and ipratropium |
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mucolytic therapy
brand: mucomyst |
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cystinuria (cystine stones in your bladder etc)
brand: capoten |
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cystitis (urinary bladder infection)
brand: cipro |
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glomerulonephritis (kidney disease, blood in urine, inflammation)
brand: solu-medrol |
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urinary incontinence
brand: detrol |
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urinary tract infection
brand: macrobid |
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urolithiasis (kidney stones) pain management
brand: voltaren |
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ceruminosis (excessive earwax)
brand: debrox |
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otitis externa (outer ear inflmmation)
brand: floxin |
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otitis media (middle ear inflammation)
brand: amoxil |
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otomycosis (fungal ear infection of outer canal)
brand: nizoral |
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allergic conjunctivitis
brand: patanol |
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bacterial conjunctvitis
brand: genoptic |
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blepharitis (eyelid infection)
brand: polytrim |
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chronic dry eye
brand: restasis |
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glaucoma (damage to optic nerve)
brand: azopt |
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superficial ocular infection
brand: maxitrol |
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| line over ss (like the line over 1t, but over two ss instead) |
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| ph of the large intestine |
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Brand: Clozaril, FazaClo
For schizophrenia, can cause drop in WBC so users need their blood checked each month |
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|
Definition
Brand: thalomid
for leprosy and painful inflammation of skin
requires STEPS registration (dangerous for unborn) |
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Term
|
Definition
Generic name: alosetron
for irritable bowel syndrome, also requires physicians entered in prescribing program because can cause bad GI reactions |
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|
Definition
generic: dofetilide
irregular heart beats can be caused--used to treat arrhythmia
so needs TIPS program |
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|
Definition
brand: tysabri for multiple sclerosis
because can cause rare brain infection, needs to be in TOUCH program |
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|
Definition
| Delays release of drug until reaches intestines, so don't irriate stomach or get messed up by acid in stomach |
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Definition
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|
Definition
| Are gummy and also for the mouth |
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|
Definition
| Alcohol-based topical solutions |
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|
Definition
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|
Definition
| Aqueous, more watery than creams |
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|
Definition
| Injection into space between dura mater and vertebral column--into cerebral spinal fluid |
|
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Term
| Why intramuscular injections? |
|
Definition
| Because volume of medicaiton larger, longer duration of action, medicine would irritate the skin |
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Term
|
Definition
| Into subarachnoid space (into your head, into crebral spinal fluid), for narc single injections (pain) and for implantable fusion pumps. reduces side effects, for very low, controlled doses |
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Term
| Short-acting bronchodilators |
|
Definition
Open airways for quick rescue relief from asthma
Albuterol, Metaproterenol, Pirbuterol, Levalbuterol, Proventil, Ventolin, Alupent, Maxair, Xopenex |
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Term
|
Definition
| control inflamation for nose, sinuses, bronchi, lungs, when inhaled |
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Term
|
Definition
| prevent histamine release and prevent inflammation that causes bronchoconstriction |
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Term
|
Definition
| Ipatropium spray blocks neurotransmitter acetylcholine, which initiates inflammation in asthma bronchoconstriction |
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Term
|
Definition
| Prevent leuktrienes, which help initiate inflammatory response in bronchoconstriction |
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Term
| Tricyclic antidepressants |
|
Definition
increase norepinephrine and serotonin, block acetylcholine
They are: amitryptyline, nortryptyline, protryptyline, imipramine, desipramine, doxepin, and clomipramine |
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Term
| Monamine Oxidase Inhibitors (MAOIs) |
|
Definition
antidepressants that block MAO receptors, allowing accumulation of monoamines like norepinephrine
They are: isocarboxazid
phenelzine
tranylcypromine |
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Term
| Selective serotonin reuptake inhibitors |
|
Definition
anti-depressants
fluoxetine (prozac)
paroxetine (paxil)
sertraline (zoloft)
citalopram (celexa)
escitalopram (lexapro)
fluvoxamine (luvox) |
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|
Term
| Low potency conventional antypsychotics |
|
Definition
developed in the 1950s for psychosis, like schizophrenia
include chlorpromazine and thioridazine |
|
|
Term
| Intermediate potency conventioanl antipsychotics |
|
Definition
developed 1950s for psychosis
perphenazine and loxapine |
|
|
Term
| high potency conventional antipsychotics |
|
Definition
developed 1950s for psychosis like schizophrenia
include trifluoperazine, fluphenazine, thiothixene, and halperidol |
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Term
|
Definition
work differently from typical antipsychotics, most work on serotonin receptors AND dopamine receptors
include: clozapine, olanzepine (zyprexa), risperidone (risperdal), quetiapine (seroquel), ziprasidone (godon), and abilify |
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Term
|
Definition
relieve nervousness, tension, etc by slowing the cns
include: alprazolam (xanax), diazepam (valium), lorazepam (ativan), oxazepam (serax), estazolam (prosom), and temazepam (restoril) |
|
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Term
|
Definition
also relieve nervousness and supress CNS, but chemically different than benzodiazepines
include: buspirone (buspar), zolpidem (ambien), zaleplon (sonata), chloral hydrate (aquachloral) |
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Term
|
Definition
CNS depressants--can be mild sedatives to total anesthesia, can be hypnotics or anticonvulsants
include: phenobarbital (luminal), barbital (veronal), and amobarbital (amylobarbitone) |
|
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Term
|
Definition
prevent rapid firing of nerves (seizure)
phentoin (dilantin), fosphenytoin (cerebyx), ethotoin (peganone), diazepam (valium), lorazepam (ativan), clonazepam (klonopin), valproic acid (depakene), divalproex sodium (depakote), carbamazepine (tegretol), primidone (mysoline), gabapentin (neurontin), oxcarbazepine (trileptal), lamotrigine (lamictal), felbamate (felbatol), levetiracetam (keppra), zonisamide (zonegran), topiramate (topamax) |
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Term
|
Definition
| levodopa/carbidopa (sinemet), tolcapon, entacopone, amantidine (symmetrel), bromocriptine (parlodel), pergolide (permax), selegiline (eldepryl), benztropine (cogentin), procyclidine (kemadrin) |
|
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Term
|
Definition
lower cholesterol by binding bile in GI tract to prevent its absorption
like cholestyramine (questran), colestipol, colesevelam (welchol) |
|
|
Term
|
Definition
regulate HMG-CoA reductase which is involved in forming cholesterol
like: fluvastatin (lescol), lovastatin (mevacor), atorvastatin (lipitor), pravastatin (pravachol), simvistatin (zocor), crestor |
|
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Term
|
Definition
stimulate enzymes that digest triglycerides and help build HDL cholesterol (good)
gemfibrozil (lopid) and fenofibrate (tricor) |
|
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Term
|
Definition
reduce blood volume and blood pressure by making you pee
hydrochlorothiazide, chlorothiazide, indapamide, chlorthalidone |
|
|
Term
|
Definition
reduce blood volume and blood pressure by making you pee
furosemide (lasix), bumetanide, torsemide |
|
|
Term
| potassium-sparing diuretics |
|
Definition
reduce blood volume and blood pressure by making you pee
spironolactone, triamterene |
|
|
Term
|
Definition
| all the ones combined with hctz that reduce blood volume and blood pressure by making you pee |
|
|
Term
|
Definition
reduce blood pressure by decreasing force and speed of heart rate, relaxing blood vessels
like: atenolol, metoprolol (toprol xl and lopressor), nadolol, propranolol (inderal), timolol, carteolol, bisoprolol, sotalol, acebutolol, carvedilol (coreg), labetolol (normodyne) |
|
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Term
|
Definition
block ACE which causes constriction of blood vessels
like: captopril (capoten), benazepril, foxinopril, lisinopril, quinapril, ramipril (altace), moexipril |
|
|
Term
| angiotensin II receptor blockers |
|
Definition
cause widening of blood vessels, block angiotensin (which tenses blood vessels)
include losartan (cozaar), valsartan (diovan), irbesartan (avapro), olmesartan (benicar) |
|
|
Term
| calcium channel blockers: dihydropyridines |
|
Definition
decrease excitatory effects of calcium on heart muscle, decreasing heart beat force, lowering blood pressure
amlodipine (norvasc), nifedipine (procardia), felodipine, nisoldipine (sular), nimodipine (nimtop) |
|
|
Term
| non-dihydropyridine calcium channel blockers |
|
Definition
decrease excitatory effects of calcium on heart muscle, decreasing heart beat force, lowering blood pressure
diltiazem (cardizem), verapamil, |
|
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Term
|
Definition
| lowers blood pressure (catapres is brand) |
|
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Term
|
Definition
| lowers blood pressure (cardura) |
|
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Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
maintain normal heart rate
lidocaine (zylocaine), tocainide (tonocard), mexiletine, quinidine, procainamide (procan), disopyramide (norpace), flecainide, amiodarone, sotalol (betapace) |
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Term
|
Definition
|
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Term
|
Definition
| (sorbitrate) (isordil) heart medicine |
|
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Term
|
Definition
| (imdur) (ismo) (monoket) heart medicine |
|
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Term
|
Definition
|
|
Term
|
Definition
stop clotting
warfarin (coumadin), heparin, enoxaparin (lovenox), dalteparin (fragmin) |
|
|
Term
|
Definition
reduce acidic juices in stomach
omeprazole (prilosec), pantoprazole (protonix), lansoprazole (prevacid), rabeprozole (aciphex), esomeprazole (nexium) |
|
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Term
|
Definition
reduces production of acidic juices in stomach
cimetidine (tagamet), ranitidine (zantac), famotidine (pepcid), nizatidine (axid) |
|
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Term
|
Definition
increase muscle contraction in upper GI, speeds up stomach emptying
metoclopramide (reglan) |
|
|
Term
| NSAIDs (non-steroidal anti-inflammatory drugs) |
|
Definition
inhibit synthesis of inflammatory, pain, and fever chemicals
ibuprofen, ketoprofen, diclofenac (voltaren), sulindac (clinoril), etodolac (lodine), ketorolac (toradol), naproxen (naprosyn, napelan), meloxicam (mobic), oxaprozin (daypro), indomethacin (indocin), nabumetone (relafen) |
|
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Term
|
Definition
block enzymes to impede chemical messengers of inflammation and pain
celebrex |
|
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Term
|
Definition
block pain receptors
controlled drugs, CIIs morphine, hydromorphone, meperidine, and fentanyl, along with minor codeine, oxycodone, propoxyphene, nalbuphine, butorphanol, dezocine, tramadol (ultram) |
|
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Term
|
Definition
| acetaminophen (tylenol) stops chemicals taht sensitize pain receptors |
|
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Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| skeletal muscle relaxants |
|
Definition
block nerve impulses to prevent abnormal muscle contractions
include carisoprodol (soma), chlorzoxazone (parafon forte), cyclobenzaprine (flexeril), metaxolone (skelaxin), methocarbamol (robaxin), orphenadrine (norflex) |
|
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Term
|
Definition
| lispro, aspart, humalog, takes 5-15 minutes |
|
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Term
|
Definition
| patient creats no insulin, insulin dependent, pancreas islet cells destroyed |
|
|
Term
| type II diabetes mellitus |
|
Definition
| non-insulin dependent, create little insulin, adult onset, resistant to insulin |
|
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Term
|
Definition
| kidneys can't conserve water |
|
|
Term
|
Definition
| regular humulin r (30-60 minutes) |
|
|
Term
| intermediate acting insulin |
|
Definition
| nph, humulin n, lente (2-4 hours, 3-4 hours) |
|
|
Term
|
Definition
| lantus, ultralente (6-10 hours), glargine (4 hours) |
|
|
Term
|
Definition
| increase insulin production in the body |
|
|
Term
|
Definition
oral hypoglycemics
chlorpropamide (diabinese), tolbutamide, glyburide, glipizide, glimepiride (amaryl) |
|
|
Term
|
Definition
oral hypoglycemics
repaglinide (prandin), neteglinide (starlix) |
|
|
Term
|
Definition
oral hypoglycemics
metformin (fortament, glucophage) |
|
|
Term
|
Definition
oral hypoglycemics
rosiglitazone (avandia), pioglitazone (actos) |
|
|
Term
| alpha-glucosidase inhibitors |
|
Definition
| oral hypoglycemics like acarbose (precose), miglitol (glycet) |
|
|
Term
| oral hypoglycemic combination agents |
|
Definition
| glucovance, metoglip, avandamet (rosiglitazone/metformin) |
|
|
Term
|
Definition
|
|
Term
|
Definition
| chemotherapy intravenous drug |
|
|
Term
| intraarterial chemotherapy |
|
Definition
| floxuridine, fluorouracil, mitomycin-c, cisplatin, streptomycin |
|
|
Term
| intralesional chemotherapy (directly into a tumor) |
|
Definition
|
|
Term
|
Definition
| paclitaxel,mitoxantrone,carboplatin,alphainterferon |
|
|
Term
| intrathecal (into spinal fluid) chemo |
|
Definition
|
|
Term
| Check incompatibility for solutions of: |
|
Definition
| calcium, magnesium, or phosphate, becaues of precipitation properties and acetate or lactate |
|
|
Term
| drugs that break down when exposed to light |
|
Definition
| amphotericin b, cisplatin, and metronidazole |
|
|
Term
| cefazolin iv stable how long at room temp? |
|
Definition
| 24 hours room temp, 96 at refrigerator |
|
|
Term
| nitroglycerine and filters? |
|
Definition
| in-line filters can cause up to 90% reduction in nitroglycerin concentration |
|
|
Term
| amphotericin b is not compatible with? |
|
Definition
|
|
Term
|
Definition
| not for sue with needles, administration sets, or filters that contain aluminum |
|
|
Term
| albumin is sometimes added to admixtures because? |
|
Definition
| it preferentially binds plastics like pvc, so the drugs don't interact with the plastic |
|
|
Term
|
Definition
| nitroglycerin, epinephrine, and physostigmine |
|
|
Term
|
Definition
| corrosive, flammable, toxic, like cyclophosphamide |
|
|
Term
|
Definition
| molecular weight divided by number of ions |
|
|
Term
|
Definition
| molecular weight/valence (valence being the number of positive or negative charges) |
|
|
Term
|
Definition
| technical, chemically pure, usp, fcc (food), acs (american chemical society), ar (analytical reagent), hplc, spectroscopic, primary |
|
|
Term
| compound formulations with water should not be used beyond ____ days at cold temperature |
|
Definition
|
|
Term
| solid and non-aqueous liquid compound formulations should not be used beyond ____ |
|
Definition
|
|
Term
|
Definition
| grinding powders in a mortar and pestle |
|
|
Term
|
Definition
| mixing two powders--start with equal amounts of small powder and big powder, mix, and then little by little add the big powder so homogenous |
|
|
Term
|
Definition
| triturating a powder with a solvent in which it is insoluble to make it smaller |
|
|
Term
|
Definition
| a viscocity enhancer for syrups with artificial sweeteners |
|
|
Term
|
Definition
| cocoa butter, synthetic triglycerides, fattibas, witepsol, for suppositories |
|
|
Term
| water soluble or miscible bases |
|
Definition
| PEG or glycerinated gelatin for suppositories |
|
|
Term
|
Definition
| from 000 (1.37 ml) to 5, with 5 the smallest (0.13 ml) |
|
|
Term
|
Definition
| USP/NF for nonsterile compounds |
|
|
Term
|
Definition
| USP/NF for sterile compounds |
|
|
Term
| DFC (factsandcomparisons.com) |
|
Definition
| Compare medications in the same therapeutic class |
|
|
Term
| Martindale (The Complete Drug Reference) |
|
Definition
|
|
Term
| AHFS drug information (ashp.org/ahfs) |
|
Definition
| Off-label medication indications |
|
|
Term
| ashp.org Handbook on Injectable Drugs |
|
Definition
| All preparation, storage, etc information on injectible drugs |
|
|
Term
|
Definition
| Pricing information for drugs |
|
|
Term
| King's Guide to Parenteral Admixtures |
|
Definition
| stability and compatibility on injectible drugs |
|
|
Term
|
Definition
| trade and generic names, abbreviations, drug products |
|
|
Term
|
Definition
| chemical attributes of drugs |
|
|
Term
|
Definition
| references for physicians on warnings etc for drugs |
|
|
Term
|
Definition
| compounding, labelling, storace of pharmaceutical products |
|
|
Term
|
Definition
|
|
Term
|
Definition
| cytotoxic products and compounds safety regulations |
|
|
Term
|
Definition
| the medical letter on drugs and therapeutics, and the pink sheet |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| short stability medications |
|
Definition
| in IV, they expire within 1-6 hours after preparation--include sulfameth/trimethoprim, phenytoin |
|
|
Term
| alkylating agents (chemotheraphy) |
|
Definition
chemically react with DNA to prevent tumor cell reproduction
busulfan (myleran tablets), cisplatin (platinol iv), streptozocin (zanosar iv) |
|
|
Term
| antibiotics (chemotherapty) |
|
Definition
inhibit RNA synthesis and prevent tumor cell reproduction
bleomycin (blenoxane iv), doxorubicin (adriamycin pfs iv), mitomycin (mutamycin iv) |
|
|
Term
| antimetabolites (chemotherapy) |
|
Definition
| incorporate into normal cell components and alter their function, or inhibit normal function of key enzyme targets that are higher in cancer cells, include capectoabine (xeloda tablets), floxuridine (FUDR iv), fludarabine (fludara iv), methotrexate (rheumatrex tablet) |
|
|
Term
|
Definition
hormones inhibit synthesis of adrenal steroids which adrenal tumor cells need to reproduce
flutamide (eulexin capsule), megestrol (suspension, tab), triptorelin (trelstar injection), leuprolide (vaidur, eligard, lupron implant,inj) |
|
|
Term
|
Definition
bind to dna & rna so tumor cells can't reproduce
chlorambucil (leukeran tab), estramustine (emcyt capsule), mechlorethamine (mustargen iv) |
|
|
Term
|
Definition
inhibit cell division of tumors
docetaxel (taxotere iv), etoposide (vepesid iv, caps), paclitaxel (taxol iv) |
|
|
Term
| topoisomerase i inhibitors chemo |
|
Definition
cause DNA damage when cells replicate
irinotecan (camptosar iv), topotecan (hycamtin iv) |
|
|
Term
| fluid ounce (apothecary system) |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| adult dosage times child's weight over 150 kg |
|
|
Term
|
Definition
| adult dosage times child's age over child's age plus 12 |
|
|
Term
|
Definition
| complex two different concentrations of creams together with this method |
|
|
Term
|
Definition
|
|
Term
| flouroquinolone loses effectiveness when mixed with: |
|
Definition
|
|
Term
| warfarin's effects become increased with: |
|
Definition
| heparin, lovastatin, bactrim, metronidazole, erythromycin, clarithromycin, and cipro. |
|
|
Term
| warfarin's bleeding effects increase with: |
|
Definition
| acetaminophen, aspirin, NSAIDs. |
|
|
Term
| carbamazepine has increased effects with: |
|
Definition
| cimetidine (tagamet), erythromycin, clarithormycin, and fluconazole. |
|
|
Term
| carbamazepine has decreased effects with: |
|
Definition
|
|
Term
| phenytoin levels increase with: |
|
Definition
| cimetidine, ertyrhomycin, clarithromycin, fluconazole. |
|
|
Term
| phenytoin levels decrease with: |
|
Definition
|
|
Term
| phenobarbital levels increase with: |
|
Definition
| cimetidine, erythromycin, clarithromycin, fluconazole, and rifampin. |
|
|
Term
| lithium levels increase with: |
|
Definition
|
|
Term
| oral contraceptives decrease in effectiveness with: |
|
Definition
| rifampin, antibiotics, and troglitazone. |
|
|
Term
| viagra can cause a dramatic drop in blood pressure with: |
|
Definition
|
|
Term
| viagra can have increased levels with: |
|
Definition
| cimetidine, ertyrhomycin, itraconazole, ketoconazole. |
|
|
Term
| tricyclic antidepressants have increased levels with: |
|
Definition
| SSRI drugs like prozac and escitalopram. |
|
|
Term
| SSRI drugs have increased potential for seizures and serrotonin syndrome with: |
|
Definition
|
|
Term
| SSRI drugs cause serotonin syndrome with: |
|
Definition
| St. John's Wort, naratriptan, rizatriptan, sumatriptan, and zolmitriptan. |
|
|
Term
| bisphosphonates like alendronate and risendronate have reduced effectiveness with: |
|
Definition
|
|
Term
| anticoagulants like warfarin have reduced effectiveness and increased clotting risks with: |
|
Definition
| foods high in vitamin K like broccoli, brussels sprouts, spinach, and kale. |
|
|
Term
| grapefruit juice reduces metabolism of which drugs? |
|
Definition
| some benzodiazepines, calcium channel blockers, cyclosporine, estrogen, and oral contraceptives, and certain statin drugs. |
|
|
Term
| digoxin loses absorption with what foods? |
|
Definition
| oatmeal and other fibrous foods. |
|
|
Term
| MAO inhibitors like phenelzine and tranylcypromine cause severe headache and potentially fatal blood pressure increase with: |
|
Definition
| foods high in tyramine like cheese, yogurt, cured meats, dried fish, caviar, avocados, bananas, raisins, sauerkraut, red wine, beers, and caffeine. |
|
|
Term
| tetracycline loses absorption with: |
|
Definition
|
|
