Term
| Risk factors for developing schizophrenia |
|
Definition
Age: early adulthood
Birth in late winter/early spring
Growing up in an urban environment
Stressful life events
Cannabis use
Genetic link
Viral infection in pregnancy, fetal hypoxia, greater paternal age, malnutrition or gestational DM |
|
|
Term
| First gen antipsychotic med names |
|
Definition
|
|
Term
| Second gen antipsychotic med names (atypical) |
|
Definition
|
|
Term
| AA from all antipsychotic drugs regardless of gen |
|
Definition
Sedation
Anticholinergic effects
Orthostatic hypotension |
|
|
Term
|
Definition
Less likely to cause EPS but more likely to cause metabolic effects
Weight Gain
DM
Hyperlipidemia |
|
|
Term
| FGA - Haloderidol vs chlorpromazine |
|
Definition
| Chlorpromazine has low potency Halodol is high potency |
|
|
Term
|
Definition
| Dementia pts - increased risk of death |
|
|
Term
|
Definition
EPS
Parkinsonism
Akathisia
Tardive Dyskinesia
Neuroleptic malignant syndrome
Anticholinergic effects, sedation, orthostatic HTN,
Seizures,
Sexual dysfunction |
|
|
Term
|
Definition
Early reaction of FGA more likely in higher potency
Movement disorders |
|
|
Term
| How to treat acute dystonia |
|
Definition
|
|
Term
| How to treat parkinsinsms |
|
Definition
| Anticholinergis or switch to SGA |
|
|
Term
|
Definition
| Benzodiazepine, b-blocker or anticholinergic |
|
|
Term
| Rardive Dyskinesia treatment |
|
Definition
| Benzodiazepines, reduce dose or switch to SGA |
|
|
Term
| Neuroleptic Malignant Syndrome SX |
|
Definition
Lead pipe rigidity
Sudden high fever
Sweating
Autonomic instability manifested as dysrhythmias and fluctuations in BP
Decreased LOC
Respiratory failure
More likely with high potency FGA |
|
|
Term
|
Definition
Anticholinergics - intensifies aa, avoid antihistamines
CNS depressants - increase sedation
LEvodopa/dopamine agonist - counteract antipsychotic effects |
|
|
Term
| Rardive Dyskinesia treatment |
|
Definition
| Benzodiazepines, reduce dose or switch to SGA |
|
|
Term
| Neuroleptic Malignant Syndrome SX |
|
Definition
Lead pipe rigidity
Sudden high fever
Sweating
Autonomic instability manifested as dysrhythmias and fluctuations in BP
Decreased LOC
Respiratory failure
More likely with high potency FGA |
|
|
Term
|
Definition
Anticholinergics - intensifies aa, avoid antihistamines
CNS depressants - increase sedation
LEvodopa/dopamine agonist - counteract antipsychotic effects |
|
|
Term
|
Definition
Positive symptoms can be thought of as an addition to normal cognition. Things we don’t normally have such as hallucinations, delusions, word salad...
Negative symptoms diminish normal functions. Such as altered affect, lack of goal directed behavior (grooming or self care) lack of energy and social isolation. |
|
|
Term
| 5 domains os schizophrenia |
|
Definition
| Delusions, hallucinations, disorganized thinking, disorganized or abnormal motor behavior including catatonia, and negative symptoms |
|
|
Term
|
Definition
May be related to excessive dopamine
Genetic link
May be related to virus
Correlated with ventricular enlargement and thinning of prefrontal cortex |
|
|
Term
|
Definition
| Block receptors for dopamine, ACH, histamine, and norepi |
|
|
