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NEUROLEPTICS
PSYCHOPHARMACOLOGY
339
Psychology
Not Applicable
09/03/2017
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Term
Chlorpramazine is a ______ generation antipsychotic.
 Definition
first
Term
Fluphenazine is a ______ generation antipsychotic.
 Definition
first
Term
Hapoperodial is a ______ generation antipsychotic.
 Definition
first
Term
Loxapine is a ______ generation antipsychotic.
 Definition
first
Term
Mesoridazine is a ______ generation antipsychotic.
 Definition
first
Term
Molindone is a ______ generation antipsychotic.
 Definition
first
Term
Perphenazine is a ______ generation antipsychotic.
 Definition
first
Term
Pimozide is a ______ generation antipsychotic.
 Definition
first
Term
Thioridazine is a ______ generation antipsychotic.
 Definition
first
Term
Thiothizene is a ______ generation antipsychotic.
 Definition
first
Term
Triflouroperizene is a ______ generation antipsychotic.
 Definition
first
Term
Asenapine is a ______ generation antipsychotic.
 Definition
second
Term
Clozapine is a ______ generation antipsychotic.
 Definition
second
Term
Iloperidone is a ______ generation antipsychotic.
 Definition
second
Term
Olanzapine is a ______ generation antipsychotic.
 Definition
second
Term
Paliperidone is a ______ generation antipsychotic.
 Definition
second
Term
Quetiapine is a ______ generation antipsychotic.
 Definition
second
Term
Risperidone is a ______ generation antipsychotic.
 Definition
second
Term
Ziprasidone is a ______ generation antipsychotic.
 Definition
second
Term
Lurasidone is a ______ generation antipsychotic.
 Definition
second
Term
Ariprizole is a ______ generation antipsychotic.
 Definition
third
Term
The brand name(s) for chlorpramazine is/are:
 Definition
Thorazine
Term
The brand name(s) for fluphenazine is/are:
 Definition
Prolixin, Permitil, Anatensol, Prolixin, Decanoate
Term
The brand name(s) for hapoperodial is/are:
 Definition
Haldol
Term
The brand name(s) for loxapine is/are:
 Definition
Loxitane
Term
The brand name(s) for mesoridazine is/are:
 Definition
Serentil
Term
The brand name(s) for molindone is/are:
 Definition
Moban
Term
The brand name(s) for perphenazine is/are:
 Definition
Trilofan
Term
The brand name(s) for pimozide is/are:
 Definition
Orap
Term
The brand name(s) for thioridazine is/are:
 Definition
Mellaril
Term
The brand name(s) for thiothizene is/are:
 Definition
Navane
Term
The brand name(s) for triflouroperizene is/are:
 Definition
Stelazine
Term
The brand name(s) for asenapine is/are:
 Definition
Saphris
Term
The brand name(s) for clozapine is/are:
 Definition
Clozaril
Term
The brand name(s) for iloperidone is/are:
 Definition
Fanapt
Term
The brand name(s) for olanzapine is/are:
 Definition
Zyprexa
Term
The brand name(s) for paliperidone is/are:
 Definition
Invega
Term
The brand name(s) for quetiapine is/are:
 Definition
Seroquel
Term
The brand name(s) for risperidone is/are:
 Definition
Risperdal
Term
The brand name(s) for ziprasidone is/are:
 Definition
Geodon
Term
The brand name(s) for lurasidone is/are:
 Definition
Latuda
Term
The brand name(s) for ariprizole is/are:
 Definition
Abilify
Term
Chlorpramazine is a ______ generation antipsychotic.
 Definition
first
Term
Fluphenazine is a ______ generation antipsychotic.
 Definition
first
Term
Haloperodial is a ______ generation antipsychotic.
 Definition
first
Term
Loxapine is a ______ generation antipsychotic.
 Definition
first
Term
Mesoridazine is a ______ generation antipsychotic.
 Definition
first
Term
Molindone is a ______ generation antipsychotic.
 Definition
first
Term
Perphenazine is a ______ generation antipsychotic.
 Definition
first
Term
Pimozide is a ______ generation antipsychotic.
 Definition
first
Term
Thioridazine is a ______ generation antipsychotic.
 Definition
first
Term
Thiothizene is a ______ generation antipsychotic.
 Definition
first
Term
Triflouroperizene is a ______ generation antipsychotic.
 Definition
first
Term
Asenapine is a ______ generation antipsychotic.
 Definition
second
Term
Clozapine is a ______ generation antipsychotic.
 Definition
second
Term
Iloperidone is a ______ generation antipsychotic.
 Definition
second
Term
Olanzapine is a ______ generation antipsychotic.
 Definition
second
Term
Paliperidone is a ______ generation antipsychotic.
 Definition
second
Term
Quetiapine is a ______ generation antipsychotic.
 Definition
second
Term
Risperidone is a ______ generation antipsychotic.
 Definition
second
Term
Ziprasidone is a ______ generation antipsychotic.
 Definition
second
Term
Lurasidone is a ______ generation antipsychotic.
 Definition
second
Term
Ariprizole is a ______ generation antipsychotic.
 Definition
third
Term
The brand name(s) for chlorpramazine is/are:
 Definition
Thorazine
Term
The brand name(s) for fluphenazine is/are:
 Definition
Prolixin, Permitil, Anatensol, Prolixin, Decanoate
Term
The brand name(s) for haloperodial is/are:
 Definition
Haldol
Term
The brand name(s) for loxapine is/are:
 Definition
Loxitane
Term
The brand name(s) for mesoridazine is/are:
 Definition
Serentil
Term
The brand name(s) for molindone is/are:
 Definition
Moban
Term
The brand name(s) for perphenazine is/are:
 Definition
Trilofan
Term
The brand name(s) for pimozide is/are:
 Definition
Orap
Term
The brand name(s) for thioridazine is/are:
 Definition
Mellaril
Term
The brand name(s) for thiothizene is/are:
 Definition
Navane
Term
The brand name(s) for triflouroperizene is/are:
 Definition
Stelazine
Term
The brand name(s) for asenapine is/are:
 Definition
Saphris
Term
The brand name(s) for clozapine is/are:
 Definition
Clozaril
Term
The brand name(s) for iloperidone is/are:
 Definition
Fanapt
Term
The brand name(s) for olanzapine is/are:
 Definition
Zyprexa
Term
The brand name(s) for paliperidone is/are:
 Definition
Invega
Term
The brand name(s) for quetiapine is/are:
 Definition
Seroquel
Term
The brand name(s) for risperidone is/are:
 Definition
Risperdal
Term
The brand name(s) for ziprasidone is/are:
 Definition
Geodon
Term
The brand name(s) for lurasidone is/are:
 Definition
Latuda
Term
The brand name(s) for ariprizole is/are:
 Definition
Abilify
Term
What three conditions are neuroleptics used to treat?
 Definition
Schizophrenia, severe depression, and bipolar disorder
Term
Neuroleptics may also be used to treat brief psychotic epsiodes caused by ____.
 Definition
Drugs of abuse
Term
What seven neuroleptics show positive effects across a range of disorders?
 Definition
Risperdal, Saphris, Fanapt, Zyprexa, Seroquel, Geodon, Abilify
Term
_______ and ________ are used adjunctively to treat depression.
 Definition
ariprizole and quetiapine
Term
These seven neuroleptics stabilize mood and are used to treat bipolar disorder.
 Definition
Risperdal, Saphris, Fanapt, Zyprexa, Seroquel, Geodon, Abilify
Term
______ can also be used as a short-term anxiolytic.
 Definition
Trifluoperazine
Term
T/F: Early, acute symptoms may be treated with higher doses of medication then reduced once stabilization occurs.
 Definition
True
Term
Many neuroleptics are taken ____ a day.
 Definition
Once
Term
T/F: Many neuroleptics are taken before bed to take advantage of their drowsiness side effect.
 Definition
True
Term
Some neuroleptics may be taken by injection _______ per month.
 Definition
once or twice
Term
_____ antipsychotics work on both positive and negative symptoms of schizophrenia.
 Definition
Atypical
Term
Atypical antipsychotics affect _____ and ______ neurotransmitter pathways.
 Definition
dopamine, seratonin
Term
_____ antipsychotics have been FDA approved for the treatment of depression.
 Definition
Atypical
Term
First generation antispychotics are also called ______ antispychotics.
 Definition
typical
Term
Second generation antispychotics are also called ______ antispychotics.
 Definition
atypical
Term
Atypical antipsychotics are less likely to produce serious side effects such as ____ and ____.
 Definition
tardive dyskinesia, neuroleptic malignant syndrome
Term
Atypical antipsychotics that may cause Neurolepric Malignant Syndrome are ____ and ____.
 Definition
Olanzapine, Risperidone
Term
Chlorpramazine is a ______ generation antipsychotic.
 Definition
first
Term
Fluphenazine is a ______ generation antipsychotic.
 Definition
first
Term
Haloperodial is a ______ generation antipsychotic.
 Definition
first
Term
Loxapine is a ______ generation antipsychotic.
 Definition
first
Term
Mesoridazine is a ______ generation antipsychotic.
 Definition
first
Term
Molindone is a ______ generation antipsychotic.
 Definition
first
Term
Perphenazine is a ______ generation antipsychotic.
 Definition
first
Term
Pimozide is a ______ generation antipsychotic.
 Definition
first
Term
Thioridazine is a ______ generation antipsychotic.
 Definition
first
Term
Thiothizene is a ______ generation antipsychotic.
 Definition
first
Term
Triflouroperizene is a ______ generation antipsychotic.
 Definition
first
Term
Asenapine is a ______ generation antipsychotic.
 Definition
second
Term
Clozapine is a ______ generation antipsychotic.
 Definition
second
Term
Iloperidone is a ______ generation antipsychotic.
 Definition
second
Term
Olanzapine is a ______ generation antipsychotic.
 Definition
second
Term
Paliperidone is a ______ generation antipsychotic.
 Definition
second
Term
Quetiapine is a ______ generation antipsychotic.
 Definition
second
Term
Risperidone is a ______ generation antipsychotic.
 Definition
second
Term
Ziprasidone is a ______ generation antipsychotic.
 Definition
second
Term
Lurasidone is a ______ generation antipsychotic.
 Definition
second
Term
Ariprizole is a ______ generation antipsychotic.
 Definition
third
Term
The brand name(s) for chlorpramazine is/are:
 Definition
Thorazine
Term
The brand name(s) for fluphenazine is/are:
 Definition
Prolixin, Permitil, Anatensol, Prolixin, Decanoate
Term
The brand name(s) for haloperodial is/are:
 Definition
Haldol
Term
The brand name(s) for loxapine is/are:
 Definition
Loxitane
Term
The brand name(s) for mesoridazine is/are:
 Definition
Serentil
Term
The brand name(s) for molindone is/are:
 Definition
Moban
Term
The brand name(s) for perphenazine is/are:
 Definition
Trilofan
Term
The brand name(s) for pimozide is/are:
 Definition
Orap
Term
The brand name(s) for thioridazine is/are:
 Definition
Mellaril
Term
The brand name(s) for thiothizene is/are:
 Definition
Navane
Term
The brand name(s) for triflouroperizene is/are:
 Definition
Stelazine
Term
The brand name(s) for asenapine is/are:
 Definition
Saphris
Term
The brand name(s) for clozapine is/are:
 Definition
Clozaril
Term
The brand name(s) for iloperidone is/are:
 Definition
Fanapt
Term
The brand name(s) for olanzapine is/are:
 Definition
Zyprexa
Term
The brand name(s) for paliperidone is/are:
 Definition
Invega
Term
The brand name(s) for quetiapine is/are:
 Definition
Seroquel
Term
The brand name(s) for risperidone is/are:
 Definition
Risperdal
Term
The brand name(s) for ziprasidone is/are:
 Definition
Geodon
Term
The brand name(s) for lurasidone is/are:
 Definition
Latuda
Term
The brand name(s) for ariprizole is/are:
 Definition
Abilify
Term
What three conditions are neuroleptics used to treat?
 Definition
Schizophrenia, severe depression, and bipolar disorder
Term
Neuroleptics may also be used to treat brief psychotic epsiodes caused by ____.
 Definition
Drugs of abuse
Term
What seven neuroleptics show positive effects across a range of disorders?
 Definition
Risperdal, Saphris, Fanapt, Zyprexa, Seroquel, Geodon, Abilify
Term
_______ and ________ are used adjunctively to treat depression.
 Definition
ariprizole and quetiapine
Term
These seven neuroleptics stabilize mood and are used to treat bipolar disorder.
 Definition
Risperdal, Saphris, Fanapt, Zyprexa, Seroquel, Geodon, Abilify
Term
______ can also be used as a short-term anxiolytic.
 Definition
Trifluoperazine
Term
T/F: Early, acute symptoms may be treated with higher doses of medication then reduced once stabilization occurs.
 Definition
True
Term
Many neuroleptics are taken ____ a day.
 Definition
Once
Term
T/F: Many neuroleptics are taken before bed to take advantage of their drowsiness side effect.
 Definition
True
Term
Some neuroleptics may be taken by injection _______ per month.
 Definition
once or twice
Term
_____ antipsychotics work on both positive and negative symptoms of schizophrenia.
 Definition
Atypical
Term
Atypical antipsychotics affect _____ and ______ neurotransmitter pathways.
 Definition
dopamine, seratonin
Term
_____ antipsychotics have been FDA approved for the treatment of depression.
 Definition
Atypical
Term
First generation antispychotics are also called ______ antispychotics.
 Definition
typical
Term
Second generation antispychotics are also called ______ antispychotics.
 Definition
atypical
Term
Atypical antipsychotics are less likely to produce serious side effects such as ____ and ____.
 Definition
tardive dyskinesia, neuroleptic malignant syndrome
Term
Atypical antipsychotics that may cause Neurolepric Malignant Syndrome are ____ and ____.
 Definition
Olanzapine, Risperidone
Term
DEF: CNS disorder characterized by twitching of the face and tongue and involuntary motoro movements.
 Definition
tardive dyskinesia
Term
The most common side effects of antispychotic medications are _____ (5).
 Definition
sedation, hypotension, anticholinergic effects, sexual dysfunction, and extrapyramidal symptoms.
Term
What are four commonly reported anticholinergic side effects of antipsychotics?
 Definition
dry mouth, urinary retention or hesistancy, constipation, visual disturbances
Term
Risperidone and ziprasidone may produce this side effect.
 Definition
hyperprolactinemia
Term
Ziprasidone and thioridazine may produce this side effect.
 Definition
cardiac arrhythmia
Term
Cardiac arrhythmia is indicated by what symptoms?
 Definition
palpitations, dizziness, fainting, shortness of breath, chest discomfort
Term
Clozapine can produce what side effect?
 Definition
agranulocytosis
Term
What is agranulocytosis?
 Definition
a severe and dangerous leukopenia (lowered white blood cell count)
Term
Metabolic syndrome issues are seen in ____ and ____ antipsychotics.
 Definition
first generation, second generation
Term
What metabolic syndrome issues are commonly reported with FGA and SGA?
 Definition
weight gain, hyperglycemia, dyslipidemia
Term
What is dyslipidemia?
 Definition
An abnormal amount of lipids (cholesterol and/or fat) in the blood
Term
What two neuroleptics are considered "high risk" for metabolic syndrome issues?
 Definition
clozapine and olanzapine
Term
What neuroleptic is considered "moderate risk" for metabolic syndrome issues?
 Definition
quetiapine
Term
What three neuroleptics present the lowest risk for metabolic syndrome issues?
 Definition
ariprizole, risperidone, ziprasidone
Term
The most common mild side effects of neuroleptics are ____ and ____.
 Definition
sedation, agitation
Term
The most worrisome side effects of neuroleptics are ____ and ____.
 Definition
weight gain, elevated blood sugar/lipds
Term
Use of FGA may lead to _______, though it's unknown if it's a direct effect or a secondary effect of obesity.
 Definition
diabetes mellitus
Term
Clozapine can rarely cause serious abnormalities in blood cells called ____.
 Definition
blood dyscrasias
Term
Approximately ____ to ____ % of clozapine patients develop agranulocytosis.
 Definition
1, 2
Term
Clozapine patients must be registered with the _____.
 Definition
TEVA Clozapine Patient Registry
Term
To avoid agranulocytosis, clozapine patients must have the WBC count every ____ for ____ months.
 Definition
week, six
Term
If a clozapine use does not develop agranulocytosis within th efirst 6 months, their WBC count is then monitored every ____ weeks for ____ months.
 Definition
two, six
Term
Risperidone and olanzipene are known as ____ antipsychotics.
 Definition
high potency
Term
____ and ____ are known as "high potency" antipsychotics.
 Definition
risperidone, olanzipene
Term
____ is one of the most notorious antipsychotics for causing hyperprolactimenia.
 Definition
risperidone
Term
Risperidone is one of the most notorious antipsychotics for causing ____.
 Definition
hyperprolactimenia
Term
At higher doses, risperidone can have a ____ effect.
 Definition
sedative
Term
Risperidone may cause ____, _____, _____, and _____.
 Definition
involuntary movements, tremors, muscular rigidity, and immobility wthout paralysis
Term
As many as ____% of men and ____% of women using risperidone have experienced hyperprolactimenia.
 Definition
40, 60
Term
As many as 40% of men and 60% of women using risperidone have experienced ____.
 Definition
hyperprolactimenia
Term
As many as 40% of men and 60% of women using ____ have experienced hyperprolactimenia.
 Definition
risperidone
Term
Olanzipene is highly ____ and has a high tendency to cause weight gain and other metabolic changes.
 Definition
sedating
Term
____ is highly sedating and has a high tendency to cause weight gain and other metabolic changes.
 Definition
Olanzipene
Term
Olanzipene is highly sedating and has a high tendency to cause ____ and other metabolic changes.
 Definition
weight gain
Term
____ long-acting injections can be administered every two weeks.
 Definition
Risperidone
Term
Risperidone long-acting injections can be administered every ____ weeks.
 Definition
two
Term
____ has antipsychotic properties and higher doses and antidepressant properties at lower doses.
 Definition
Quetiapine
Term
Quetiapine has ____ properties and higher doses and ____ properties at lower doses.
 Definition
antipsychotic, antidepressant
Term
____ is used in the acute and maintenance phases of schizophrenia and bipolar depression.
 Definition
Quetiapine
Term
Quetiapine is used in the ____ and ____ phases of schizophrenia and bipolar depression.
 Definition
acute, maintenance
Term
Quetiapine is used in the acute and maintenance phases of ____ and ____.
 Definition
schizophrenia, bipolar depression
Term
Chlorpramazine is a ______ generation antipsychotic.
 Definition
first
Term
Fluphenazine is a ______ generation antipsychotic.
 Definition
first
Term
Haloperodial is a ______ generation antipsychotic.
 Definition
first
Term
Loxapine is a ______ generation antipsychotic.
 Definition
first
Term
Mesoridazine is a ______ generation antipsychotic.
 Definition
first
Term
Molindone is a ______ generation antipsychotic.
 Definition
first
Term
Perphenazine is a ______ generation antipsychotic.
 Definition
first
Term
Pimozide is a ______ generation antipsychotic.
 Definition
first
Term
Thioridazine is a ______ generation antipsychotic.
 Definition
first
Term
Thiothizene is a ______ generation antipsychotic.
 Definition
first
Term
Triflouroperizene is a ______ generation antipsychotic.
 Definition
first
Term
Asenapine is a ______ generation antipsychotic.
 Definition
second
Term
Clozapine is a ______ generation antipsychotic.
 Definition
second
Term
Iloperidone is a ______ generation antipsychotic.
 Definition
second
Term
Olanzapine is a ______ generation antipsychotic.
 Definition
second
Term
Paliperidone is a ______ generation antipsychotic.
 Definition
second
Term
Quetiapine is a ______ generation antipsychotic.
 Definition
second
Term
Risperidone is a ______ generation antipsychotic.
 Definition
second
Term
Ziprasidone is a ______ generation antipsychotic.
 Definition
second
Term
Lurasidone is a ______ generation antipsychotic.
 Definition
second
Term
Ariprizole is a ______ generation antipsychotic.
 Definition
third
Term
The brand name(s) for chlorpramazine is/are:
 Definition
Thorazine
Term
The brand name(s) for fluphenazine is/are:
 Definition
Prolixin, Permitil, Anatensol, Prolixin, Decanoate
Term
The brand name(s) for haloperodial is/are:
 Definition
Haldol
Term
The brand name(s) for loxapine is/are:
 Definition
Loxitane
Term
The brand name(s) for mesoridazine is/are:
 Definition
Serentil
Term
The brand name(s) for molindone is/are:
 Definition
Moban
Term
The brand name(s) for perphenazine is/are:
 Definition
Trilofan
Term
The brand name(s) for pimozide is/are:
 Definition
Orap
Term
The brand name(s) for thioridazine is/are:
 Definition
Mellaril
Term
The brand name(s) for thiothizene is/are:
 Definition
Navane
Term
The brand name(s) for triflouroperizene is/are:
 Definition
Stelazine
Term
The brand name(s) for asenapine is/are:
 Definition
Saphris
Term
The brand name(s) for clozapine is/are:
 Definition
Clozaril
Term
The brand name(s) for iloperidone is/are:
 Definition
Fanapt
Term
The brand name(s) for olanzapine is/are:
 Definition
Zyprexa
Term
The brand name(s) for paliperidone is/are:
 Definition
Invega
Term
The brand name(s) for quetiapine is/are:
 Definition
Seroquel
Term
The brand name(s) for risperidone is/are:
 Definition
Risperdal
Term
The brand name(s) for ziprasidone is/are:
 Definition
Geodon
Term
The brand name(s) for lurasidone is/are:
 Definition
Latuda
Term
The brand name(s) for ariprizole is/are:
 Definition
Abilify
Term
What three conditions are neuroleptics used to treat?
 Definition
Schizophrenia, severe depression, and bipolar disorder
Term
Neuroleptics may also be used to treat brief psychotic epsiodes caused by ____.
 Definition
Drugs of abuse
Term
What seven neuroleptics show positive effects across a range of disorders?
 Definition
Risperdal, Saphris, Fanapt, Zyprexa, Seroquel, Geodon, Abilify
Term
_______ and ________ are used adjunctively to treat depression.
 Definition
ariprizole and quetiapine
Term
These seven neuroleptics stabilize mood and are used to treat bipolar disorder.
 Definition
Risperdal, Saphris, Fanapt, Zyprexa, Seroquel, Geodon, Abilify
Term
______ can also be used as a short-term anxiolytic.
 Definition
Trifluoperazine
Term
T/F: Early, acute symptoms may be treated with higher doses of medication then reduced once stabilization occurs.
 Definition
True
Term
Many neuroleptics are taken ____ a day.
 Definition
Once
Term
T/F: Many neuroleptics are taken before bed to take advantage of their drowsiness side effect.
 Definition
True
Term
Some neuroleptics may be taken by injection _______ per month.
 Definition
once or twice
Term
_____ antipsychotics work on both positive and negative symptoms of schizophrenia.
 Definition
Atypical
Term
Atypical antipsychotics affect _____ and ______ neurotransmitter pathways.
 Definition
dopamine, seratonin
Term
_____ antipsychotics have been FDA approved for the treatment of depression.
 Definition
Atypical
Term
First generation antispychotics are also called ______ antispychotics.
 Definition
typical
Term
Second generation antispychotics are also called ______ antispychotics.
 Definition
atypical
Term
Atypical antipsychotics are less likely to produce serious side effects such as ____ and ____.
 Definition
tardive dyskinesia, neuroleptic malignant syndrome
Term
Atypical antipsychotics that may cause Neurolepric Malignant Syndrome are ____ and ____.
 Definition
Olanzapine, Risperidone
Term
DEF: CNS disorder characterized by twitching of the face and tongue and involuntary motoro movements.
 Definition
tardive dyskinesia
Term
The most common side effects of antispychotic medications are _____ (5).
 Definition
sedation, hypotension, anticholinergic effects, sexual dysfunction, and extrapyramidal symptoms.
Term
What are four commonly reported anticholinergic side effects of antipsychotics?
 Definition
dry mouth, urinary retention or hesistancy, constipation, visual disturbances
Term
Risperidone and ziprasidone may produce this side effect.
 Definition
hyperprolactinemia
Term
Ziprasidone and thioridazine may produce this side effect.
 Definition
cardiac arrhythmia
Term
Cardiac arrhythmia is indicated by what symptoms?
 Definition
palpitations, dizziness, fainting, shortness of breath, chest discomfort
Term
Clozapine can produce what side effect?
 Definition
agranulocytosis
Term
What is agranulocytosis?
 Definition
a severe and dangerous leukopenia (lowered white blood cell count)
Term
Metabolic syndrome issues are seen in ____ and ____ antipsychotics.
 Definition
first generation, second generation
Term
What metabolic syndrome issues are commonly reported with FGA and SGA?
 Definition
weight gain, hyperglycemia, dyslipidemia
Term
What is dyslipidemia?
 Definition
An abnormal amount of lipids (cholesterol and/or fat) in the blood
Term
What two neuroleptics are considered "high risk" for metabolic syndrome issues?
 Definition
clozapine and olanzapine
Term
What neuroleptic is considered "moderate risk" for metabolic syndrome issues?
 Definition
quetiapine
Term
What three neuroleptics present the lowest risk for metabolic syndrome issues?
 Definition
ariprizole, risperidone, ziprasidone
Term
The most common mild side effects of neuroleptics are ____ and ____.
 Definition
sedation, agitation
Term
The most worrisome side effects of neuroleptics are ____ and ____.
 Definition
weight gain, elevated blood sugar/lipds
Term
Use of FGA may lead to _______, though it's unknown if it's a direct effect or a secondary effect of obesity.
 Definition
diabetes mellitus
Term
Clozapine can rarely cause serious abnormalities in blood cells called ____.
 Definition
blood dyscrasias
Term
Approximately ____ to ____ % of clozapine patients develop agranulocytosis.
 Definition
1, 2
Term
Clozapine patients must be registered with the _____.
 Definition
TEVA Clozapine Patient Registry
Term
To avoid agranulocytosis, clozapine patients must have the WBC count every ____ for ____ months.
 Definition
week, six
Term
If a clozapine use does not develop agranulocytosis within th efirst 6 months, their WBC count is then monitored every ____ weeks for ____ months.
 Definition
two, six
Term
Risperidone and olanzipene are known as ____ antipsychotics.
 Definition
high potency
Term
____ and ____ are known as "high potency" antipsychotics.
 Definition
risperidone, olanzipene
Term
____ is one of the most notorious antipsychotics for causing hyperprolactimenia.
 Definition
risperidone
Term
Risperidone is one of the most notorious antipsychotics for causing ____.
 Definition
hyperprolactimenia
Term
At higher doses, risperidone can have a ____ effect.
 Definition
sedative
Term
Risperidone may cause ____, _____, _____, and _____.
 Definition
involuntary movements, tremors, muscular rigidity, and immobility wthout paralysis
Term
As many as ____% of men and ____% of women using risperidone have experienced hyperprolactimenia.
 Definition
40, 60
Term
As many as 40% of men and 60% of women using risperidone have experienced ____.
 Definition
hyperprolactimenia
Term
As many as 40% of men and 60% of women using ____ have experienced hyperprolactimenia.
 Definition
risperidone
Term
Olanzipene is highly ____ and has a high tendency to cause weight gain and other metabolic changes.
 Definition
sedating
Term
____ is highly sedating and has a high tendency to cause weight gain and other metabolic changes.
 Definition
Olanzipene
Term
Olanzipene is highly sedating and has a high tendency to cause ____ and other metabolic changes.
 Definition
weight gain
Term
____ long-acting injections can be administered every two weeks.
 Definition
Risperidone
Term
Risperidone long-acting injections can be administered every ____ weeks.
 Definition
two
Term
____ has antipsychotic properties and higher doses and antidepressant properties at lower doses.
 Definition
Quetiapine
Term
Quetiapine has ____ properties and higher doses and ____ properties at lower doses.
 Definition
antipsychotic, antidepressant
Term
____ is used in the acute and maintenance phases of schizophrenia and bipolar depression.
 Definition
Quetiapine
Term
Quetiapine is used in the ____ and ____ phases of schizophrenia and bipolar depression.
 Definition
acute, maintenance
Term
Quetiapine is used in the acute and maintenance phases of ____ and ____.
 Definition
schizophrenia, bipolar depression
Term
____ and ____ have moderate sedative and few weight gain, diabetes or lipid effects.
 Definition
Ziprasidone, ariprizole
Term
Ziprasidone and ariprizole have ___ sedative and few weight gain, diabetes or lipid effects.
 Definition
moderate
Term
Ziprasidone and ariprizole have moderate ____ and few ____, ____ or ____ effects.
 Definition
sedative, weight gain, diabetes, lipid
Term
____ and _____ have a less predictable antipsychotic response.
 Definition
Ziprasidone, ariprizole
Term
Ziprasidone and ariprizole have a ____ response.
 Definition
less predictable antipsychotic
Term
Ziprasidone has been linked to a serious heart condition called ____.
 Definition
torsades de pointes
Term
Ziprasidonemay cause sudden cardiac death through its effect on ____.
 Definition
QTc prolongation
Term
Paliperidone and iloperidone are antipsychotics related to ____.
 Definition
risperidone
Term
Paliperidone and iloperidone cause moderate ____ and ____.
 Definition
sedation, weight gain
Term
Paliperidone can cause ___, ____, and ____.
 Definition
EPS, hyperprolactinemia, dyslipidemia
Term
____ can cause EPS, hyperprolactinemia, and dyslipidemia.
 Definition
Paliperidone
Term
Iloperidone can cause ____ and ____.
 Definition
dyslipidemia, orthostatic hypotension
Term
____ can cause dyslipidemia and orthostatic hypotension.
 Definition
Iloperidone
Term
Paliperidone injections provide ____ worth of medication in one dose.
 Definition
one month
Term
____ is the newest SGA available in the U.S.
 Definition
Asenapine
Term
____ antipsychotics are cheaper than ____ antipsychotics.
 Definition
FGA, SGA
Term
____ antipsychotics have fewer side effects and broader treatment response than ____ antipsychotics.
 Definition
SGA, FGA
Term
The four main types of EPS are ____, ____, ____, and ____.
 Definition
pseudoparkinsonism, akathisia, acute dystonia, tardive dyskinesia
Term
____ is the only EPS that is thought to be irreversible if not countered early.
 Definition
Tardive dyskinesia
Term
____ is an EPS commonly seen in people with long-term exposure to high doses of FGA.
 Definition
Tardive dyskinesia
Term
____ are commonly found in FGA but are also seen in high potency SGA.
 Definition
EPS
Term
EPS are commonly found in ____ but are also seen in high potency ____.
 Definition
FGA, SGA
Term
____ medications such as benztropine are used to manage discomfort associated with EPS.
 Definition
Anticholinergic
Term
Anticholinergic medications such as ____ are used to manage discomfort associated with EPS.
 Definition
benztropine
Term
Anticholinergic medications such as benztropine are used to manage discomfort associated with ____.
 Definition
EPS
Term
____ describes a group of risk factors that raise your risk for heart disease, stroke, and diabetes.
 Definition
Metabolic syndrome
Term
Metabolic syndrome describes a group of risk factors that raise your risk for ____, ____, and ____.
 Definition
heart disease, stroke, and diabetes
Term
Five primary symptoms associated with metabolic syndrome are ____, ____, ____, ____, and ____.
 Definition
large waistline, high triglycerides, low HDL, HBP, and high fasting blood sugar
Term
Six secondary symptoms associated with metabolic syndrome are ____, ____, ____, ____, ____, and ____.
 Definition
excessive thirst/hunger, fatigue, frequent urination, headaches, slow healing of cuts/bruises, weight loss
Term
The ____, ____, and _____ can increase the risk of developing NMS.
 Definition
use of high-potency antipsychotics, a rapid increase in dose, and the use of long-acting forms of medication
Term
The use of high-potency antipsychotics, a rapid increase in dose, and the use of long-acting forms of medication can increase the risk of developing ____.
 Definition
NMS
Term
The potential for abuse for antipsychotics is ____.
 Definition
low
Term
One antipsychotic reportedly abused for self-treatment of anxiety or insomnia is ____.
 Definition
quetiapine
Term
Physical dependence across the class of neuroleptic medications is ____.
 Definition
rare
Term
Three medications used to mitigate movement-based withdrawal symptoms from neuroleptics are ___, ____, and ____.
 Definition
benztropins, diphenhydramine, and trihexphenydyl
Term
Black box warnings have ben issued for both FGA and SGA regarding use by ____ patients with ____.
 Definition
elderly, dementia.
Term
Antipsychotic medication should not be used during the ____ trimester of pregnancy.
 Definition
first
Term
Under what four conditions would antipsychotics be indicated for a woman in her first trimester of pregnancy?
 Definition
danger to herself, to others, to the unborn child, or profound psychosis
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