Term
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Definition
Pharmacology: Neurotoxic to dopaminergic neurons decreasing DA function
Effects: Parkinson's symptoms, decrease in cognition |
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Term
| Acetyl Choline Inhibitors |
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Definition
Pharmacolgy: muscarinic an nicotinic acetyl choline receptor (mAChR and nAChR) competitive and noncompetitive antagonists
Effects:Increase in heart rate and decreased cognitive function |
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Term
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Definition
Pharmacology: DA (Dopamine) and NE (norepinephrine) transporter inhibitor/releaser (through the transporter)
Effects:Increased heart rate (HR) and blood pressure (BP), addiction |
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Term
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Definition
Pharmacology: Old (typical) - DA D2 antagonists, New (atypical) - D2 antagonists and 5-HT antagonists
Effects: Loss in cognition and Parkinsonian-like symptoms |
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Term
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Definition
Pharmacology: mAChR antagonist
Effects: Decreased GI action, decreased saliva |
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Term
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Definition
Pharamcology: GABA receptor agonist
Effects: Anti-convulsant, anxiolytic |
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Term
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Definition
Pharmacology: GABA receptor allosteric modulator (noncompetitive agonist)
Effects: Anti-convulsant, anxionlytic |
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Term
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Definition
Pharmacology: Atypical antipsychotic, D2 and 5-HT antagonist
Effects: Sedation, depression-like symptoms (acutely) |
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Term
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Definition
Pharmacology: Opiate receptor competitive agonist
Effects: Analgesia, constipation |
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Term
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Definition
Pharmacology: Tricyclic
Effects: Sedation, constipation |
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Term
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Definition
Pharmacology: "Classic benzodiazepine", allosteric modulator of GABA receptor
Effects: Anti-convulsant, anxiolytic |
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Term
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Definition
Pharmacology: Blocks metabolism of acetylaldehyde by blocking acetylaldehyde dehydrogenase
Effects: Headache, facial flushing |
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Term
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Definition
Pharmacology: SSRI that inhibits 5-HT reuptake
Effects: Insomnia, sexual disfunction |
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Term
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Definition
Pharmacology: "Classic" antipsychotic, D2 antagonist
Effects: Treat schizophrenia, decreased cognition |
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Term
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Definition
Pharmacology: NMDA (which mimics glutamate) receptor competitive antagonist
Effects: Analgesia, anesthesia |
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Term
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Definition
Pharmacology: Is DA's precursor --> upregulates DA and its systems' activation
Effects: Short term can treat Parkinsons, long term use can cause schizophrenia |
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Term
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Definition
Pharmacology: Inhibit activity of monoamine oxidase preventing the breakdown of monoamine NT's (DA, NE, 5-HT)
Effects: Addiction, insomnia |
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Term
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Definition
Pharmacology: Enhances 5-HT release and inhibits 5-HT reuptake, enhances DA release
Effects: Increased HR, anxiogenesis |
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Term
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Definition
Pharmacology: µ-opioid agonist
Effects: Analgesis, depressed breathing |
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Term
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Definition
Pharmacology: DA re-uptake inhbitor of transporter
Effects: Increase in concentration, headache |
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Term
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Definition
Pharmacology: GABA receptor allosteric modulator/noncompetitive agonist
Effects: Anticonvulsant, anxiolytic |
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Term
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Definition
Pharmacology: Opiate receptor antagonist
Effects: Blocks alcohol's "euphoria", lower paintolerance |
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Term
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Definition
Pharmacology: SSRI
Effects: Insomnia, sexual disfunction |
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Term
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Definition
Pharmacology: B-andrenoceptor antagonist (blocks effects of adrenogens like epinephrine and NE)
Effects: Lowers BP, anxiolytic |
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Term
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Definition
Pharmacology: 5-HT2A competitive agonist
Effects: Increased HR, hallucinations |
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Term
| SSRI's (Selective Serotonin Reuptake Inhibitors) |
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Definition
Pharmacology: Inhibits 5-HT reuptake
Effects: Acute anxiogenesis, sexual disfunction |
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Term
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Definition
Pharmacology: Muscarinic AChR antagonist
Effects: Decreased GI activity, decreased saliva |
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Term
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Definition
Pharmacology: SSRI
Effects: Insomnia, sexual disfunction |
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Term
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Definition
Pharmacology: ACh esterase inhibitor (don't break down ACh --> its effects are upregulated)
Effects: Increased digestion, increased HR |
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Term
| Tricyclic Antidepressants |
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Definition
Pharmacology: 5-HT and NE reuptake inhibitors
Effects: Sedation, constipation |
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Term
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Definition
Pharmacology: 5-HT and NE reuptake inhibitor
Effects: Acute depression-like symptoms, anxyolitic |
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