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Definition
| scientific study of the uses, actions, and effects of drugs |
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| effects of drugs on the functioning of the cells in the nervous system |
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| effects of drugs on mood, thinking, and behavior |
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| scientific study of how drugs interact with the nervous system to affect mood, thinking, and behavior |
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Definition
| attributes that trigger participants to subconsciously change their behavior based on their interpretation of the experiment |
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| the amount of a drug in the blood that is available to bind at specific target sites in order to elicit a drug action |
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Definition
| heavy metal replaces the Ca ions in the body |
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Definition
| alimentary/GI routes of administration (oral and rectal) are known as... |
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Definition
| which route of administration is safer and more comfortable with little risk of overdose? |
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Definition
| routes of administration that do not use the GI tract |
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| inhalation, topical, and transdermal routes of administration are all... |
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Definition
| route of administration characterized by absorption through the lungs |
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Definition
| route of administration that refers to application on mucous membranes (sublingual, intranasal) |
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Definition
| route of administration that involves a patch delivering a sustained amount of a drug through the skin |
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Definition
| ___ ROA used for motion sickness, vaccines, nicotine, and hormones |
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Definition
| drugs administered to the CSF in order to bypass the blood-brain barrier |
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Definition
| drugs (antibiotics) are delivered in a constant dose to the CSF in the ventricles of the brain |
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Term
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Definition
| when a drug is mixed with equal volumes of water and lipid solvent, this is the ratio of the amount of drug in the oil to the amount in the water |
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Term
| heart, brain, kidneys, liver |
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Definition
| what organs receive the most blood flow? |
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Term
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Definition
| This is a chemical trigger zone in the brainstem medulla that induces vomiting when toxic substances are detected |
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Definition
| This part of the brain borders the hypothalamus and contains capillary fenestrations that allow hormones to move to the pituitary gland |
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Definition
| Which drug can cross the blood-brain barrier and is used to treat intoxication from agricultural pesticides? |
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Definition
| What drug does not cross the blood-brain barrier and can be used to treat myasthenia gravis? |
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Definition
| What can occur if a pregnant mother's blood contains high levels of heroin, alcohol, cocaine, cigarettes, or CO? |
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Definition
| What term is used to describe fetal developmental abnormalities resulting from exposure to therapeutic drugs, illicit drugs, radiation, and some infections? |
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Term
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Definition
| When is a fetus most susceptible to teratogenic effects? |
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Term
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Definition
| what aspect of pharmacology can be used to describe the exponential decrease or half-life of a drug? |
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Term
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Definition
| what takes place via zero order kinetics and occurs when drug levels are high and routes of metabolism and elimination are saturated, resulting in constant rate of molecule clearance? |
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Term
| Phase I, Non-synthetic reactions |
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Definition
| What type of reactions occur before a second metabolic step and modify a drug via redox reactions or hydrolysis? |
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Term
| Phase II, Synthetic reactions |
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Definition
| What type of metabolism requires a drug to conjugate with a small molecule to produce ionized forms? |
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Term
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Definition
| what can occur through urine, breath, sweat, saliva, feces, or breast milk? |
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Term
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Definition
| drug competition, age, gender, genetics, enzyme induction, and enzyme inhibition can all affect ___. |
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Term
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Definition
| What enzyme is responsible for oxidizing psychoactive drugs and is found in the liver, intestines, kidneys, lungs, and nasal passages? |
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