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Psychopathology
Schizophrenia (T Pierce)
13
Medical
Post-Graduate
02/04/2009

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Cards

Term
Definition of schizophrenia
Definition
severe, chronic psychotic illness which results in decline in long term psychosocial and occupational functioning
Term
Characteristics symptoms of schizo
Definition
  • hallucinations- perception w/o ext. stimuli
  • delusions- firmly held erroneous beliefs incongruent with culture
  • disorganization
  • grossly disorganized behavior/catatonic behavior
  • "negative symptoms"
Term
Examples of negative symptoms
Definition
  • affective flattening
  • diminish emotional expressiveness
  • apathy
  • anergia
  • asociality
  • attentional impairment
  • avolition- inability to initiate and persist in goal directed activities
  • alogia- poverty of speech and its content
Term

Define milder symptoms of schizo

Definition

similar to active symptoms, but less intense

Term
What would exclude somebody from being schizo?
Definition
  • prominent affective states
  • contributory substance, medication, or medical condition
  • autism/PDD (developmental disorder)
Term
Phases of schizo
Definition
  • prodromal (subtle changes)
  • active (psychotic symptoms develop)
  • interepisode (new baseline of functioning)
  • residual (attenuated positive symptoms, impact of negative symptoms, re-emergence of active phase symptoms)
Term
epidemiology of schizophrenia
Definition
  • usually mean age of 21 for me and 27 for women
  • seen in winter births, first degree relatives of schizophrenics
  • gestational/delivery complications
  • afflicts slightly more men than women
Term
neuropathology of schizophrenia
Definition
  • increase ventricular size
  • decrease brain volume
  • abnormal migration of neurons
  • loss of normal cortical asymmetry (you should have larger left side, but schizo has more symmetrical brain)
  • increase glutamate (ex: PCP bind NMDA R)

OVERACTIVITY OF DOPAMINE (drugs that antagonize dopamine)

Term
Treatment of schizophrenia
Definition
  • evaluate for patient safety
  • antipsychotic medication
  • no specific treatment for negative symptoms
  • adjunctive medications (ex: for agitation, moods, impulsivity)
  • NMDA receptor modulators in near future
Term
psychosocial interventions in schizophrenia
Definition
  • partial hospitalizations
  • case management
  • family interventions
  • support group
  • job training, rehab
  • treatment of co-morbid substance abuse
  • cognitive behvioral and supportive psychotherapies
Term
Different types of "schizos"
Definition
  • acute psychotic (symptoms less than month)
  • schizophreniform (symptoms (1-6 mnths)
  • schizophrenia (symptoms more than 6 mnths)
Term

Symptoms of schizoid personality disorder

Definition
  • loner personality
  • weak interpersonal skills
  • difficulty expressing anger, even when provoked
Term

Symptoms of schizotypal personality

Definition
  • odd, eccentric mannerisms, appearance
  • odd beliefs or magical thinking
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