Term
| methylphenidate, dextroamphetamine |
|
Definition
| release stored catecholamines (esp NE and DA) |
|
|
Term
|
Definition
4 h dystonia
4 d akinesia -- Parkinsonism
4 wk akathisia -- restlessness
4 mo tardive dyskinesia |
|
|
Term
random side effects
chlorpromazine
thioridazine
olanzapine
clozapine |
|
Definition
Chlorpromazine -- Corneal deposits
Thioridazine -- reTinal deposits
olanzapine -- weight gain
clozapine -- agranulocytosis, weight gain |
|
|
Term
| neuroleptic malignant syndrome -- symptoms, treatment |
|
Definition
FEVER
Fever
Encephalopathy
Vitals unstable
Elevated enzymes (myoglobin)
Rigidity
dantrolene, D2 agonists (bromocriptine) |
|
|
Term
high-potency vs. low-potency
which antipsychotics treat positive AND negative symptoms |
|
Definition
high-potency -- more EPS
low-potency -- more anti-cholinergic, anti-histamine, alpha blockade
atypical -- positive AND negative symptoms |
|
|
Term
|
Definition
LMNOP
Lithium
Movement (tremor)
Nephrogenic DI
hypOthyroidism
Pregnancy problems |
|
|
Term
| drugs that increase lithium levels |
|
Definition
excreted in PCT of kidneys!!
thiazides, ACEi, NSAIDs |
|
|
Term
|
Definition
|
|
Term
|
Definition
| TCA -- block reuptake of NE and 5-HT |
|
|
Term
|
Definition
| TCA -- block reuptake of NE and 5-HT |
|
|
Term
|
Definition
| TCA -- block reuptake of NE and 5-HT |
|
|
Term
|
Definition
| TCA -- block reuptake of NE and 5-HT |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| drugs that cause serotonin syndrome |
|
Definition
SSRI, SNRI, MAOi, TCA
tramadol, meperidine
ondansetron
linezolid
triptans |
|
|
Term
| symptoms and treatment of serotonin syndrome |
|
Definition
autonomic stim (i.e. hyperthermia, tachy, diaphoretic, V/D)
neuromusc excitation (i.e. myoclonus, clonus, hyperreflex, rigid, tremor)
AMS (i.e. seizures, agitation, confusion)
cyproheptadine (5-HT2 receptor antagonist) |
|
|
Term
|
Definition
Tri-C's
Convulsions
Coma
Cardiotoxicity --> give NaHCO3
inhibition of fast Na+ channels --> arrhythmias --> hypotension --> death
TCAs + MAOIs = seizures!! |
|
|
Term
|
Definition
hypertensive crisis with typramine --> give phentolamine
TCAs + MAOIs --> seizures |
|
|
Term
| buproprion -- mechanisms, side effects |
|
Definition
increase NE and dopamine
nicotinic receptor antagonist --> smoking cessation
seizure!! |
|
|
Term
| mirtazapine -- mechanisms, side effects |
|
Definition
pre-synaptic alpha2 antagnoist --> increased NE and 5-HT release
5-HT2 and 5-HT3 receptor antagnoist
sedation, increase appetite |
|
|
Term
|
Definition
|
|
Term
| trazodone -- mechanism, side effect |
|
Definition
inhibits 5-HT reuptake
priapism!! |
|
|
Term
|
Definition
| partial nicotinic receptor agonist --> smoking cessation |
|
|
Term
| sexual dysfunction and anti-depressants |
|
Definition
SSRIs bad
buproprion good! |
|
|
Term
|
Definition
mostly mu; miosis is kappa!!
naloxone/naltrexone highest affinity for mu! |
|
|
Term
| time between d/c MAOi and start SSRI |
|
Definition
| 14 days, to let MAO re-generate!! |
|
|
Term
|
Definition
high potency, typical antipsychotics
block D2 receptors
Try to Fly High |
|
|
Term
|
Definition
high potency, typical antipsychotics
block D2 receptors
Try to Fly High |
|
|
Term
|
Definition
high potency, typical antipsychotics
block D2 receptors
Try to Fly High |
|
|
Term
|
Definition
low potency, typical antipsychotics
block D2 receptors
Cheating Thieves are low |
|
|
Term
|
Definition
low potency, typical antipsychotics
block D2 receptors
Cheating Thieves are low |
|
|
Term
|
Definition
atypical antipsychotics
varied DA, 5-HT2 effects
it's atypical for OLd CLOSets to QUIETly RISPER from A to Z |
|
|
Term
|
Definition
atypical antipsychotics
varied DA, 5-HT2 effects
it's atypical for OLd CLOSets to QUIETly RISPER from A to Z |
|
|
Term
|
Definition
atypical antipsychotics
varied DA, 5-HT2 effects
it's atypical for OLd CLOSets to QUIETly RISPER from A to Z |
|
|
Term
|
Definition
atypical antipsychotics
varied DA, 5-HT2 effects
it's atypical for OLd CLOSets to QUIETly RISPER from A to Z |
|
|
Term
|
Definition
atypical antipsychotics
varied DA, 5-HT2 effects
it's atypical for OLd CLOSets to QUIETly RISPER from A to Z |
|
|
Term
|
Definition
atypical antipsychotics
varied DA, 5-HT2 effects
it's atypical for OLd CLOSets to QUIETly RISPER from A to Z |
|
|
Term
|
Definition
MAO inhibitors -- decresaed degradation of 5-HT, NE, DA
MAO Takes Pride In Shanghai |
|
|
Term
|
Definition
MAO inhibitors -- decresaed degradation of 5-HT, NE, DA
MAO Takes Pride In Shanghai |
|
|
Term
|
Definition
MAO inhibitors -- decresaed degradation of 5-HT, NE, DA
MAO Takes Pride In Shanghai |
|
|
Term
|
Definition
selective MAO-B inhibitor -- decreased degradation of DA only
MAO Takes Pride In Shanghai |
|
|
