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| combination drug therapy used when a patient's condition does not respond adequately to a single drug or when a given combination of medications is known to have therapeutic benefits over a single drug |
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| emotional disorders that are characterized by changes in mood |
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| fear of leaving the familiar setting of home |
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| motor restlessness - a distressing experience of uncontrollable muscular movements that can occur as an adverse effect of many psychotropic medications |
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| Any substance capable of reducing the physiologic and pharmacologic effects of histamine, including a wide variety of drugs that block histamine receptors |
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| of or pertaining to a medication that counteracts or diminishes symptoms of psychosis. (older name is neuroleptic) |
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| the unpleasant state of mind in which real or imagined dangers are anticipated and or exaggerated |
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| Capable of reducing anxiety, usually said of a medication |
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| the most common group of psychotropic drugs currently prescribed to alleviate anxiety |
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| Biogenic Amine Hypothesis (BAH) |
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Definition
| theory suggesting that depression and mania are due to alterations in neruonal and synaptic amine concentrations, primarily the catecholamines dopamine and norepinephrine, as well as the indolamines serotonin and histamine |
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| a major psychologic disorder characterized by episodes of mania or hypomania, cycling with depression |
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| a special warning required by the FDA in the commercial drug labeling for drugs that have shown a pattern of major adverse effects |
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| an abnormal emotional state characterized by exaggerated feelings of sadness, melancholy, dejection, wortlessness, emptiness, and hoplessness that are inappropriate and out of proportion to reality |
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| views dopamine dysregulation in certain parts of the brain as one of the primary contributing factors to the development of psychotic disorders |
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| views depression and affective disorders as not simply decreased or increased catecholamine and serotonin activity but as failures of the regulation of these systems |
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| Refers to symptoms arising adjacent to the pyrimidal portions of the brain. Such symptoms involve various motion disorders similar to Parkinson's disease and are an adverse effect associated with use of various antipsychotic drugs |
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| Gamma-Aminobutyric Acid (GABA) |
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Definition
| an inhibitory amino acid in the brain that functions to inhibit nerve transmission in the CNS |
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| A state characterized by an expansive emotional state; extreme excitement; excessive elation; hyperactivity; agitation; over-talkativeness; flight of ideas; increased psychomotor activity; fleeting attention; and sometimes violent, destructive, and self-destructive behavior |
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| Monoamine Oxidase Inhibitor (MAOI) |
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Definition
| any of a heterogeneous group of drugs used primarily in the treatment of depression |
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| pharmacologic therapy involving a single medication for a specific condition |
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| Neuroleptic malignant syndrome |
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Definition
| refers to an uncommon but serious adverse effect associated with use of antipsychotic drugs and including such symptoms as fever, cardiovascular instability, and myoglobinemia |
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Definition
| Endogenous chemical in the body that serves to conduct nerve impulses between nerve cells. |
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| implicates reduced concentrations of serotonin as the predisposing factor in individuals with affective disorders |
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| a type of serious mental illness that can take xseveral different forms and is associated with being truly out of touch with reality, that is, unable to distinguish imaginary from real circumstances and events |
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| refers to the therapy of emotional and mental disorders. It may involve drug therapy, a variety of counseling techniques, recreational therapy, and, in extreme cases, ECT |
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| Capable of affecting mental processes; usually said of a medication |
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| Selective Serotonin Reuptake Inhibitor (SSRI) |
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Definition
| Any of a heterogeneous group of newer medications used to treat depression and certain other mental illnesses. They work by selectively reducing postsynaptic reuptake of the neurotransmitter serotonin in the brain |
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Definition
| A collection of symptoms resulting from excessive activity of the neurotransmitter serotonin in the brain; may occur with any psychotropic drugs that enhance brain serotonin activity |
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Definition
| widespread negative perceptions of and prejudice toward a specific group of people such as those with mental illness |
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Definition
| A serious drug adverse effect involving disordered body movements and muscle tension that is associated with antipsychotic medications |
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Definition
| A chemical class of antidepressant drugs that block reuptake of the amine neurotransmitters serotonin and norepinephrine. They are so named because their chemical structures include a distinctive three-ring segment |
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