Term
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Definition
| Protein that competes for iron |
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Term
| who produces it (human or bug)? |
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Definition
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Term
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Definition
| to compete for iron required by bacteria for growth |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| free DNA incorporated into competent cell. |
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Term
| What is a siderophore and why do bugs produce them? |
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Definition
| iron-chelator that competes with iron-binding proteins of host. |
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Term
| In addition to Adhesin proteins, Gram (positive or negative?) bugs also use Teichoic and Lipoteichoic acid filaments for adherence. |
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Definition
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Term
| Where do you find adhesin proteins on a bug? |
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Definition
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Term
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Definition
| Antibody (opsonin) coats the surface of a bug to enhance phagocytosis. |
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Term
| Secondary Lysosomal Hydrolases (lysozyme, phospholipase, ribonuclease, deoxyribonuclease, protease) are: Oxygen INdependent or Dependent? |
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Definition
| Oxygen independent. Function is enhanced by low pH of vacuoles. |
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Term
| Name the stages of movement for a PMN to exit circulation and move toward exposed site. |
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Definition
| 1) Rolling. 2) Activation. 3) Adhesion. 4) Diapedesis. |
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Term
| HOST DEFENSES: 2nd line defenses are (specific OR non-specific)? Give an example of one. |
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Definition
| NON-specific. Example is Inflammation |
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Term
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Definition
| basophil, eosinophil, neutrophil. These all have cytoplasmic granules visible on microscopy. |
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Term
| What is the approx % of circulating neutrophils in blood (as a percentage of total WBCs)? |
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Definition
55% - 90%.
Never Let Monkeys Eat Bananas |
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Term
| Where can you find the secretory antibacterial IgA, as its used in a 1st line of defense? |
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Definition
| saliva, breast milk, mucous covering the respiratory, intestinal and urinary tracts. |
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Term
| what 3 reactive oxygen intermediates are produced in lysosomes in the oxygen dependent killing of bugs? |
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Definition
| hydroxyl radicals, superoxide radicals, hydrogen peroxide. |
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Term
| What does PAMP stand for? |
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Definition
Pathogen-Associated Molecular Pattern.
*recognized by toll-like receptors in both plants and animals. |
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Term
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Definition
| 1) ingestion. 2) intracellular digestion (in phagolysosome). 3) Exocytosis. |
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Term
| 3 examples for 1st line of defense: |
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Definition
| 1) skin. 2) normal flora. 3) secreted antibacterial products (lysozyme, IgA, lactoferrin). |
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Term
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Definition
| destroys peptidoglycan layer |
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