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PSU nutrition
final exam for PSUs ch 250
128
Chemistry
Undergraduate 2
06/05/2011

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Term
List the B vitamins
Definition
thiamin
riboflavin
niacin
B6
folate
B12
Biotin
Panthothenic acid
Term
What are the fat soluble vitamins?
Definition
Vitamin A, D, E and K
Term
What is a vitamin?
Definition
an organic compound required in small amounts in the diet (less than a gram) they promote regular chemical reactions, growth, reproduction and maintenance of health
Term
what is Fortification?
Definition
vitamins added to foods through fortification
Term
what is enrichment?
Definition
Term
What function does vitamin c serve?
Definition
-antioxidant in body fluids to protect:
-blood
-dna
-WBC
-lining of lungs and stomach mucosa
-deactivates hisamine
-helps form collagen
Term
Sources of Vitamin C?
Definition
found in fruits/veg as ascorbic acid
-citrus
-green peppers
-brocolli
spinach
strabwerries
romain lettuce
kiwi
brussel sprouts
Term
What is Scurvy?
Definition
caused by Vitamin c deficiency
fatigue
hemmorhages
bleeding gums
loose teeth
muscle degeneration
bone fragility and death
Term
Toxicity of Vitamin C?
Definition
excess is removed from bodily fluids
high doses can result in diarrhea nausea and cramps
Term
Who needs to consume more vit c?
Definition
smokers
Term
What are the different forms of vitamin B?
Definition
Thiamin
Roboflavin
Niacin
B6
folate
B12
biotin
pantothenic acid
Term
What is the general function of B vitamins?
Definition
coenzymes!

which are non protein molecules that act as carriers of electrons or atoms in metabolic reactions
Term
What is the function of Thiamin?
Definition
aka B1
part of coenzyme Tpp
Term
What are srouces of Thiamin?
Definition
pork
sunflower seeds
whole grains
legymes
enriched grains
Term
What happens when one is deficient in thiamin?
Definition
beriberi- muscle weakness, edema, depression, nervous system and heart damage
Term
What is the function of Riboflavin?
Definition
aka B12

coenzyme in the release of energy from nutrients

part of FMN and FAD in the TCA cycle and breakdown of fatty acids and the ETC
Term
Sources of Riboflavin?
Definition
milk
grains
liver
oysters
brewers yeast
Term
deficient in riboflavin =?
Definition
is a condition called ariboflavinosis which is when cell growth is retarded
a decrease in healing rapid in the skin and eyes and lips
usually in combo with other deficiencies
Term
Functions of Niacin?
Definition
a coenzyme NAD/NADH and NADP and is involved in oxidation/reduction reactions
Term
sources of niacin?
Definition
enriched grains
beef
chicken
turkey
fish or tryptophan
Term
deficient in niacin = ?
Definition
results in pellegra!
s/s
rough/raw skin
4 d's: dermatitis, diarrhea, dementia and death
decreased appetitie and weight
Term
What is pellegra?
Definition
caused by a niacin deficiency

usually caused by eatin too much corn or white rice
Term
Toxicity of niacin?
Definition
flushing of skin
itching
nausea and liver damage
Term
Vitamin B6 functions?
Definition
-transamination reactions
main coenzyme is PLP which activates enzymes needed for metabolism of sugs fats and protein

synthesis of Hb and histamine
gene expression
Term
sources of vitamin b6?
Definition
meat
fish
poultry
whoel grains
bananas
spinach
Term
Who needs to take Niacin suplements?
Definition
alcholoics and ppl on meds that decrease b6's
Term
toxicity of vitamin B6?
Definition
only from supplements
can lead to nerve damage
Term
FOlate functions?
Definition
coenzyme THEA
necessary for DNA and RNA synthesis
cell division
rapid cell turnover
amino acid metabolism
Term
deficiency of folate?
Definition
impairs cell division and protein synthesis
megablastic anemia
preggo + neural tube defects
Term
who needs to consume more B 6?
Definition
POOR DIET
ELDERLY
ALCOHOLIC
KIDNEY DIALYSIS
LIVER DISEASE
Term
who is at risk for folate deficiencies?
Definition
alcholoics
maabsorptive liver disease
kidney dislysis
Term
sources of folate?
Definition
*leafy greens
*liver
grains
*legumes
veg
fort cereals
Term
toxicity of folate?
Definition
only from supplements
skin/respiratory disorders
epilepsey
excess can mask B12 deficiency
Term
B12 functions?
Definition
-helps convert COA to sCOA in the TCA cycle
recycles folate enxymes
nerve function
maintain myelin sheaths
prevents megaplastic anemia
Term
sources of B12?
Definition
sythensized by bacteria in intestines
live
animal products
some yeasts
Term
deficiency of B12?
Definition
-usually due to decreased absorption abilits and decrease in gastic acids(elderly)

pernicious anemia
nerve damage
weakness
paralysis
death
Term
Functions of Biotin?
Definition
aka vitamin d
is a coenzyme in the TCA cycle
glucose synthesis
metabolism offatty acids and amino acids
Term
sources of Biotin?
Definition
califlower
yolk
liver
peanuts
cheese
Term
deficiency of biotin?
Definition
very rare (have little numbers)
from raw eggs or anticoagulant drugs

-nausea
thinning hair/hair loss
loss of hair color
skin rashes
depression
hallucinations
tingling
Term
Panthothenic acids?
Definition
*coenzyme A* for metablism of fat,sugar and protein

from meatt, mushrooms liver and peanuts

deficiency: rare seen in sevear malnutrition usually
Term
do deficiencies usually occur alone?
Definition
no except beriberi and pellegra
Term
Vitamin A functions?
Definition
part of the visual pigment rhodopsin
regulates growth and d/dx of cells
gene expression
sperm development
favors bone formation
maintence of epithelial tissues
Term
What is nigh blindness?
Definition
inadequate amounts of retinal(vit a form) to reform rhodopsin
needed for night vision
Term
Retinoic acids function?
Definition
influences hoe epithelial cells d/dx and mature
(vit a)
Term
Xeroprithalamia
Definition
major cause of blindness ( VIt a deficiency)
Term
follicular hyperkeratosis
Definition
skin disorder from low levels of vitamin a
Term
vitamin A's role in immunity?
Definition
maintains protective barriers (epi and mucus)
helps produce lymphocytes and Ab's
Term
sources of Vitamin A?
Definition
preformes: liver, fish oils fortified milk and eggs
pumpkin pie?

proformes: dark leafy greens yellow/orange fruit/veg
Term
Beta carotene functions/sources/deficiency?
Definition
-weak antioxidant, oxidation of LDL's in cell membranes

from fruits/veg that are red/orange and yellow
Term
deficiency of beta carotene?
Definition
primary: uncommon
secondary: cystic fibrosis, impaired bile production, extremely low fat diets, zinc deficiency
Term
what is VADD?
Definition
vitamin A deficiency disorder
increase infection rate
night blindness
xerophthalmaddry - eyes/blind
hyperkeratosis - rough skin
Term
Vitamin A toxicity
Definition
from excess consumption of liver
taking too many supplements
polar bear liver
Term
hypercarotenemia
Definition
results from high levels in carotenoids from foods

skin turns yellow (not harmful)
Term
Carotenoid toxicity
Definition
blured visiton
liver
abnoramal decrease bone strength
birth defects
increase in lunch cancer
hypercarotenemia
Term
non preo pitamin a
Definition
cant become vitamin a
considered a phytochemical
include lycopene
Term
lycopene
Definition
tomatoes
cancer prevention
cataract prevention
Term
luetin
Definition
brocolli
brussel sprouts
spinach
kale
macular degeneration
breast cancer
Term
antioxidants
Definition
vitamins donate their electrons to the free radicals to stabilize them, some destroy the free radicals (selelnium)

ex
vit c
deta carotene
vit E
Term
Functions of Vitamin E?
Definition
acts as an antioxidant, prevents oxidation of unsaturated fatty acids
decreases chances of cataracts and bv plaques
Term
proposed functions of vitamin E?
Definition
protect against heart disease
inhibiting LDL oxidation
inhibiting plaque formation
increading eicosanioids that dencrease blood pressure and blood clot formation
Term
sources of vitamin E?
Definition
sunflower seeds
vegetable oil
almonds
nuts
leafy greens
whole grains
Term
Toxicity of Vitamin E?
Definition
from supplements and will interfear with blood clotting action of vitamin K = hemmorhage
Term
deficiency of vitamin E?
Definition
hemolytic anemia
peripheral neuralpathy
decreased bile production
very rare but occurs in infants and people with decreased fat absorption
Term
Vitamin D function?
Definition
bone growth
regulation of gene expression and cell d/dx
hormones, collagen, ca,ph,mg and Fl
regulation of blood calcium levels
Term
sources of Vitamin D?
Definition
sunlight
fatty fish
fortified milk
liver
beef
eggs
Term
Vitamin Deficiencies?
Definition
less calcium is absorber
bone matrix cant mineralize = rubbery bones
rickets
Term
What is Rickets?
Definition
caused by a vitamin D deficiency
bowed legs in children
fixed by milk fortification
Term
Who needs to consume more Vitamin D?
Definition
ppl who live in smog areas
overcast weather
short days
have dark skin
wear sunscreen
old age
Term
Vitamin Toxicity?
Definition
higher in take results in an increase in blood concentration and urine

calcium is deposited in soft tissues

cv dmaage
affects nervoud system
promotes bone loss

caused by supplementation and hyper calcemia
Term
Vitamin K function?
Definition
production of blood clotting proteitn prothrombin

involved in blood clotting

binds ca2+
Term
Sources of vitamin K?
Definition
bacteria in intestines
milk
liver
eggs
leafy greens
veg oils
Term
Vitamin K deficicency?
Definition
rare
occurs with fat malabsorption or after long term antibiotics
results in failure to form clots
interfears with anticoagulant medications
Term
Who is at risk for vitamin K deficiency?
Definition
infants with low vit k stores
intestines without bacteria
VKDB vit d defiecency dleesing
Term
what is a mineral?
Definition
an element needed by the body in small amounts for structure and to regulate reactions and bodily processed
Term
what are the bodies major positive electrolytes?
Definition
sodium and potassium!
Term
functions of Sodium?
Definition
electrolyte balance
nerve impulse transmission
muscle contraction
Term
Excess sodium =?
Definition
hypertension = 140/90
heart disease
Term
what is the dash diet/?
Definition
low na
high ca, k and mg

high fiber
low fat
med protein
Term
toxicity of sodium?
Definition
hypertension
stomach cancer
ulcers
heartburn
kidney stones
osteoperosis
Term
Functions of chloride? Toxicity? Sources?
Definition
maintains normal fluid and electrolyte balance

part of HCl in the stomach

too much = vomiting
sources: salt, meat processed foods
Term
Function of Potassium?
Definition
major cation in the intracellular fluid

fluid balance
nerve impulse
decrease BP
muscle contraction
Term
Potassium deficicency =?
Definition
poor apetite
muscle cramps
confusion
apathy
constipation
irregular HB
Term
who usually have a potassium deficiency?
Definition
alcoholics
ppl who use direutics
ana/mia
Term
toxicity of potassium?
Definition
harmless when kidneys func fine = GI upset

not: high blood potassium levels which inhibits heart function
Term
Functions of calcium?
Definition
nerve trans
muscle contractions
BP regulation
releases hormones
blood clotting
prevents colon cancer
Term
sources of calcium?
Definition
dairy
kale
tofu
canned fish
fortified bfast cereals
Term
toxicity of calcium?
Definition
constipation
increase in chances of kidney stones
interfere with absorption of zinc, iron and magnesium
Term
Calcium deficiency?
Definition
stunted growth in children
bone loss in adults
Term
What is PTH?
Definition
parathyroid hormone

-secreted when blood calcium is too low
-released from parathyroid gland
-increases blood callcium levels
Term
what is calcitonin?
Definition
-secreted by the thyroid when blood calcium levels are too high
-decreases calcium blood levels
Term
what increases the absorption on ca?
Definition
preggo
children
taking estrogen.testerone
vitamin d
calcium binding protein
acidic environment
Term
what decreases calcium absorption?
Definition
high fiber
low vitamin d
tanins
menopause
aging
Term
Function of phosphorus?
Definition
80% in bones
ATP
DNA/RNA
phospholipids
acid/base balance
Term
sources of phosphorus?
Definition
liver
dairy
soda
meats yogurt
Term
deficiency of phosphorus?
Definition
bone loss
decreased growth
poor tooth development
Term
who are the people at risk for phosphorus deficiency?
Definition
premature babies
alcoholics
elderly with poor diets
diarrhea
aluminum antacids
Term
Functions of Magnesium?
Definition
cofactors in enzymes
activaates ATP
dna/rna synthesis
nervous and cardiac function
insulin release
dilate arteries
Term
sources of magnesium?
Definition
spinach
leafy greens
sunflower seeds
garbonzo beans
aomonds
oatmeal
ww bread
chocolate
Term
magnesium deficiency =?
Definition
develops slowly
irregular heartbead
icreased blood pressure
weakness
vomiting
muscle spasms
disorientation
nausea
seizures
Term
who is at risk for MG deficiency?
Definition
ppl who use direuitcs
lots of perspiration
long term diarrhea and vomiting
alcoholics
Term
function of Iron?
Definition
hemoglobin in RBCS
myoglobin
ETC
enzyme cofactor
immune function
Term
what are the two types of iron?
Definition
heme (animal-25 %)
and
non heme (plant 17%)
Term
what increases the absorption of iron?
Definition
MEP factor
vitamin c
citric and lactic acid
Term
what decreases the absorption of iron
Definition
phylates and fibers'vegetable proteins
calcium in milk
Term
who needs to consume more Fe?
Definition
vegetarians
adolesent girls
women less than 51
Term
iron sources
Definition
cook in iron pan
clams
liver
parsley
beans
rice
Term
what causes iron deficiency?
Definition
most common, caused by blood loss, malaria, parasites, menstruration, stage of life
Term
s/s of iron deficiency?
Definition
fatigue
weakness
headaches
apathy
pallor
poor resistances to cold temps
behavioral adhd
energy metabolism impaires
Term
what causes toxicity of iron?
Definition
caused by hemochromatosis, blood transfucions, suppllements and metabolic disorders
Term
s/s of iron toxicity?
Definition
tissue damage
infection
diabetes
liver cancer
heart disease
arthritis
nausea
constipation
vomit
runs
shock
confusion
increased HR
weak pulse
Term
function of zinc?
Definition
promotes healthy immune system
cofactor
dna and protein synthesis
cell division
protein alcohol metabolic
cell membrane
eye function
wound healing
development of sexual maturity
Term
who is at risk for zinc deficiency?
Definition
alcoholica
preggos
poor nutrition
Term
sources of zinc?
Definition
animal products
oysters
red meat
shellfish
whole grains
legumes
nuts
greens
Term
deficiency of zinc = ?
Definition
inhibits copper absorption
decreases HDL
increase heart disease
runs
cramps
nausea
vomiting
depressed immune system
Term
selenium sources?
Definition
fish
meat eggs
milk
shell fish
whole grains
nuts
**brazil nuts**
Term
functio os selenium?
Definition
defend against free radicals
regulate thyroid function
play a rolein immune function

part of a group of proteins called selenoproteins
Term
selenium deficency?
Definition
muscle pain/weakness
cardiomyoapthy
keshan disease- kid heart block vessel disease
Term
who is at risk for selenium deficiency?
Definition
people with gi diseases which lower absorption

and placed where selinium is low in the soil
Term
toxicity s/s of selenium?
Definition
brittle hair
rashes
cirrhosis of the liver
Term
function of iodine?
Definition
synthesis of thyroid hormone
Term
Iodide deficiency?
Definition
enlargement of thyroid
decreased metabolic rate
Term
toxicity of iodide results in?
Definition
inhibition of thyroid hormone synthesis
Term
sources of idiodine?
Definition
chocolate milkshake
yogurt
milke
Term
who is at risk for iodine deficency?
Definition
pregos
kids get cretinism + mental retardation
Term
functions of flouride?
Definition
protects teeth from cavities
Term
deficency/.
Definition
increased risk of dental caries
Term
toxicity?
Definition
too much tap water in kids or
too much toothpaste
Term
what are the water soluable vitamins?
Definition
* B vitamins
+ thiamin
+ riboflavin
+ niacin
+ biotin
+ pantothenic acid
+ vitamin B6
+ folate
+ vitamin B12
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