Vitamin D analogs

• Calcipotriene & Calcitriol
• Primary therapy

• Primary therapy
• Retinoid  category X

• Second line agent, thick plaque areas
• high irritation

• Second line
• removes scales, usually for scalp

• Off label for psoriasis
• good for inverse or face psoriasis

• Systemic
• good for psoriatic arthritis

• Systemic oral retinoid
• Safe for long duration
• Not immunosupresive
• Not for women who will become pregnant or 3 years post.
• Pregnancy test, liver screenings, lipid screenings
• avoid alcohol

• Systemic immunosuppresant
• For cutaneous psoriasis
• Never use wih PUVA

• Systemic immunosuppresent
• Pregnancy category X

• Systemic
• good for PT that have existing liver diseases

• Etanercept (need TB test)
• Adalimunab
• Infliximab

• moderate to severe psoriasis
• done at dr. office
• affects T cells, bad for HIV

1. Anagen: growth
2. Catagen: transition
3. Telogen: restng phase
   
4. Exogen: hair falls out
5. Return to anagen

• Topical steroids
• Vit D analogs
• Tazarotene

• Coal tar
• anthralin
• salicylic acid

• Tazarotene (X)
• BRMs (D)
• Acetretin (X)
• Methotrexate (X)
• Mycophenolate (D)