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Protozoa 3
Micro Quiz 3
62
Science
Professional
11/17/2011

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Term
Hemoflagellates family
Definition
Trypanosoma
Term
The genus trypanosoma includes the major pathogens
Definition
Trypanosoma cruzi,
Trypanosoma gambiense, and
Trypanosoma rhodesiense
Term
Trypanosoma cruzi (Hemoflagellates) disease causes
Definition
Chagas disease
Term
Trypanosoma cruzi transmission life cycle involves what vector and host
Definition
the reduviid bug as the vector and both humans and animals as reservoir host.
Term
Trypanosoma cruzi (Chagas Disease) occurs primarily in
Definition
rural Central and South America
Term
Trypanosoma cruzi (Chagas Disease) occurs rarely in
Definition
the southern United States (american disease)
Term
The reduviid bug (Chagas Disease) lives in
Definition
the walls of rural huts and feeds at night
Term
The reduviid bug bites around
Definition
the mouth and eyes "kissing bug"
Term
Chagas Disease prevalent in
Definition
Bolivia; America
Term
Trypanosomiasis amastigotes can
Definition
kill cells and cause inflammation
Term
Amastigotes consist mainly of
Definition
mononuclear cells
Term
Trypanosomiasis amastigotes frequently affects the
Definition
cardiac muscle and is most severe
Term
Trypanosomiasis amastigotes neuronal damage leads to
Definition
cardiac arrhythmias, megacolon, and megaesophagus
Term
Megacolon
Definition
loss of tone in colon
Term
Megaesophagus
Definition
loss of tone in the esophagus
Term
Trypanosomiasis (Chagas Disease) clinical findings
Definition
facial edema and a nodule (chagoma) near the bite, coupled with fever, lymph adenopathy, and hepatosplenomegaly
Term
Acute phase of Trypanosomiasis (Chagas Disease) resolves in
Definition
2 months
Term
After the acute phase of Trypanosomiasis most individuals will
Definition
remain asymptomatic but some progress to the chronic form of myocarditis and megacolon
Term
Trypanosomiasis (Chagas Disease) death is due to
Definition
cardiac arrhythmias and failure
Term
Trypanosomiasis (Chagas Disease) treatment for acute phase is
Definition
nifurtimox which kills trypomastogotes in blood
Term
Nifurtimox treatment for Trypanosomiasis is ineffective against
Definition
amastigotes in tissue
Term
Trypanosomiasis treatment for the chronic form is
Definition
no effective treatment
Term
Prevention of Trypanosomiasis (Chagas Disease) is
Definition
protection from reduviid bites, improved housing, and insect control
Term
Trypanosomiasis drug or vaccine is
Definition
No prophylactic drug or vaccine is available
Term
African Trypanosomiasis disease is
Definition
T gambiense and T rhodesiense
Term
African Trypanosomiasis causes
Definition
sleeping sickeness
Term
African Trypanosomiasis transmission is the
Definition
Tsetse fly
Term
African Trypanosomiasis is endemic is
Definition
Sub Saharan Africa, which is the natural habitat of the esetse fly
Term
The trypomastigotes in African Trypanosomiasis spread
Definition
from the skin through the blood to the lymph nodes and the brain.
Term
The typical somnolence (sleeping sickness) progresses to coma as a result of
Definition
a demyelinating encephalitis.
Term
African Trypanosomiasis clinical findings are
Definition
initial lesion is an indurated skin ulcer at the site of fly bite
Term
Chagas disease is prevalent in
Definition
8-11 million people (most prevalent)
Term
African Trypanosomiasis is prevalent in
Definition
10,000 people
Term
African Trypanosomiasis after organism enter the blood stream the patient will present with
Definition
intermittent weekly fever and lymphadenopathy develop
Term
African Trypanosomiasis The encephalitis is characterized initially by
Definition
headache, insomnia and mood changes
Term
African Trypanosomiasis encephalitis is followed by
Definition
muscle tremors, slurred speech and apathy that progress to somnolence and coma.
Term
Treatment of African Trypanosomiasis must be initiated
Definition
before the development of encephalitis, because suramin, the most effective drug , does not pass the blood-brain barrier wall.
Term
Drug treatment of African Trypanosomiasis
Definition
Suramin will cure if given early. Pentamidine is an alternative drug
Term
Trypanosomiasis once it infects the body it will take the form of
Definition
amastigotes
Term
Prevention of African Trypanosomiasis
Definition
Protection against the fly bite using netting and protective clothing
Term
African Trypanosomiasis once it infects the body will take the form of
Definition
Trypomastigotes
Term
Leishmania refers to
Definition
a group of infections caused by the flagellate protozoa of the genus leishmania
Term
African Trypanosomiasis (sleeping sickness) target organ
Definition
brain
Term
clinical types of leishmaniasis
Definition
Cutaneous, Mucocutaneous and Visceral
Term
Leishmania is transmitted to humans by
Definition
the bite of a sand fly
Term
Pathogens of Leishmaniasis
Definition
L Donovani, L tropica/L mexicana, and L braziliensis
Term
Leishmania Donovani is cause of
Definition
Kala-azar (viceral leishmaniasis) "black fever"
Term
Leishmania tropica and Leishmania mexicana both cause
Definition
cutaneous leishmaniasis
Term
Leishmania braziliensis causes
Definition
mucocutaneous leishmaniasis
Term
Trypanosomiasis diseases are
Definition
chagas disease and sleeping sickness
Term
The lesions of cutaneous and mucocutaneous leishmaniasis are limited to
Definition
the skin and mucous membrane
Term
The worst type of Leishmaniasis is
Definition
viceral leishmaniasis
Term
Leishmaniasis after it infects the human will form into
Definition
promastigotes transforms to amastigotes
Term
Cutaneous leishmaniasis appears
Definition
2 to 3 weeks after the bite of an infected sand fly as a small cutaneous papule
Term
Cutaneous leishmaniasis lesion grows becoming
Definition
indurated and often ulcerated, and develops secondary infection.
Term
Leishmania Donovani patient will present with
Definition
black fever (hyperpigmentation), splenomegaly, and enlarged abdomen, intermittent fever, weakness, and weighloss
Term
Cutaneous leishmaniasis The disease is
Definition
occasionally self-limiting but usually chronic.
Term
Protozoa associated with black water fever
Definition
cerebral malaria, plasmodium falciparum malaria
Term
Kala-Azar viceral leishmaniasis runs its course for
Definition
months to years
Term
Visceral Leishmaniasis (kala-azar) treatment and prevention is
Definition
sodium stibogluconate
Term
Prevention of Visceral Leishmaniasis (kala-azar) invloves
Definition
protection from sandfly bites
Term
Visceral Leishmaniasis (kala-azar) splenomegaly patients will
Definition
70% have a good outlook
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