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Proteins D
proteins D
16
Chemistry
Undergraduate 1
11/09/2008

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Term
What is a tropocollagen?
Definition
3 polypeptide chains wrapped around each other in a ropelike twist to form a triple helix
Term
What are 3 polypeptide chains wrapped around each other in a ropelike twist
Definition
Tropocollagen
Term
In a tropocollagen, is each polypeptide chain a helix?
Definition
Yes, but not alpha helix
Term
What holds the 3 strands together in a tropocollagen?
Definition
Hydrogen bonding involving hydroxyproline and hydroxylysine
Term
What happens with age in tropocollagen helices?
Definition
Cross linked by covalent bonds fromed between lys reidues
Term
What is the definition of a quaternary structure?
Definition
Interaction of 2 or more polypeptide chains in a protein
Term
What are the chains of a quaternary structure called?
Definition
subunits
Term
Are the subunits in a quaternary structure the same or different?
Definition
can be either
Term
Does each individual chain in a quaternary structure have its own 1, 2 and 3 degree structure?
Definition
Yes
Term
What are conjugated proteins?
Definition
They contain materials other than amino acid chains
Term
What are examples of materials in conjugted proteins?
Definition
glycoproteins-sugars; lipoproteins-lipids; matals and small organic groups; hemoglobin-heme group; and prosthetic groups-non sugar or lipid group
Term
What is a conformation?
Definition
the overall structure of a protein
Term
Name 4 conformations of proteins:
Definition
primary, secondary, tertiary and quaternary
Term
What is unique about a secondary protein?
Definition
pattern is in a backbone shape with arrangement of alpha helix and beta sheaths
Term
What is unique about tertiary proteins?
Definition
3-d shape, no pattern, random coil, alpha and bets sheaths
Term
What is unique about a quaternary structure?
Definition
several protein chains come together and stick to one another
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