Term
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Definition
| TCN protein synthesis inhibitors, Short acting |
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Term
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Definition
| TCN protein synthesis inhibitors, Intermediate acting. Can use tx for SIADH |
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Term
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Definition
| TCN protein synthesis inhibitors, 2nd gen. long acting (PO/IV) OK for pt w. renal failure |
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Term
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Definition
| TCN protein synthesis inhibitors, 2nd gen. long acting (PO/IV) AE vestibular disturbances |
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Term
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Definition
| Aminoglycosides- protein synthesis inhibitor, not systemically (topical only) |
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Term
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Definition
| Aminoglycosides- protein synthesis inhibitor (IM). Indication TB, plague, tularemia |
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Term
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Definition
| Aminoglycosides- protein synthesis inhibitor. Indication serious infection ofunknown etiology, serious gm - infection, resistant bugs esp in hospitals |
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Term
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Definition
| Aminoglycosides- protein synthesis inhibitor. Indication serious infection ofunknown etiology, serious gm - infection, resistant bugs esp in hospitals |
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Term
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Definition
| Aminoglycosides- protein synthesis inhibitor. Indication serious infection ofunknown etiology, serious gm - infection, resistant bugs esp in hospitals |
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Term
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Definition
| Macrolides- protein synthesis inhibitor. similar to penicillin G, gm + cocci and bacilli. TX mycoplasma, legionelle, chlamydia. destroyed in gut |
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Term
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Definition
| Macrolides- protein synthesis inhibitor. increased activity against intracellular pathogens. TX chlamydia, legionelle, ureaplasma, active against haemophilus influenzae. stable in gut |
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Term
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Definition
| Macrolides- protein synthesis inhibitor. less active against staph & strep; active against respiratory infections- haemophilus influenzae, morazella catarrhalis. Preferred therapy for chlamydia trachomatis urethritis. Z-pak. stable in gut |
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Term
| Chloramphenicol (Chloromycetin) |
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Definition
| protein synthesis inhibitor, 50s. active against wide range gm + & - bugs, rickettsia, chlamydia. cidal/ static. very active against anaerobes |
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Term
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Definition
| protein synthesis inhibitor, 50s. Bacteriostatic. used primarily to treat anaerobic infections, especially bacteroids fragilis. |
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Term
| GI upset; tooth pigmentation & enamel hypoplasia, deposition in bone; fatal hepatotoxoicity in preggo; phototoxicity; superinfection; psuedomotor cerebri |
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Definition
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Term
| Previous mainstay treatment f serious aerobic gm - bacilli infection. narrow therapeutic index. |
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Definition
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Term
| Polycations- poor oral absorption, poor CNS penetration, rapid excretion by kidney |
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Definition
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Term
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Definition
| Bactericidal, bind irreversibly to 30s ribosomal unit. indicated for aerobic bugs, mostly gm -. |
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Term
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Definition
| Aminoglycosides- protein synthesis inhibitor. |
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Term
| Ototoxicity, nephrotoxicity, neuromuscular paralysis, |
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Definition
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Term
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Definition
| Macrolides- protein synthesis inhibitors |
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Term
| Toxicity. bone depression, aplastic anemia, gray baby syndrome, GI disturbances, superinfections |
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Definition
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Term
| Skin rashes, diarrhea, potentially fatal PMC (pseudomembranous colitis) |
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Definition
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Term
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Definition
| combat resistant gm + bugs, reserved for MRSA, VRSA, VRE, PNC resistant strept. binds to 50s. bacteriostatic/cidal |
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