| Term 
 | Definition 
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        | Term 
 | Definition 
 
        | deficiency of vit B12; IF not being secreted due to autoimmune dysfunction |  | 
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        | Term 
 | Definition 
 
        | disorder of the red bone marrow |  | 
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        | Term 
 | Definition 
 
        | genetic; inadequate production of normal hgb; abnormal production of hemoglobin (major- cant compensate) (minor-can compensate) |  | 
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        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | increased destruction (ex: sickle cell) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | malabsorption, inadequate intake, loss of iron in the blood through GI and GU system, pregnancy |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | a number of these; DNA synthesis impaired leads to defective RBC maturation; large and abnormal, destroyed easily |  | 
        |  | 
        
        | Term 
 
        | folic acid deficiency  (megaloblastic anemia) |  | Definition 
 
        | necessary for DNA synthesis leading to RBC formation and maturation |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | decreased RBC, WBC, and platelets |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Congenital or acquired due to environment, infections, medications, or idiopathic; pancytopenia |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | within the cell; defects, enzyme deficiencies, genetic factors Sickle cell
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Normal RBC, destruction by external factors: trapped in organs, antibody destruction, toxins,  mechanical destruction |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Complete blood count RBC count
 Hemoglobin
 Hematocrit
 Total iron binding capacity
 Ferratin
 Peripheral blood smear  (shape, color)
 Bone marrow
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Group of inherited disorders of mutant hemoglobin Abnormally shaped RBCs become trapped in capillaries or are damaged
 Spleen becomes non-functioning/ other organs/ stroke
 |  | 
        |  | 
        
        | Term 
 
        | Neutropenia (a descriptor not a disease) |  | Definition 
 
        | low neutrophils; Lack of inflammatory response Identify infection through temperature
 Chills/ heat sensations
 
 Avoid raw foods (because they cant fight bacteria)
 Prevent infection
 Avoid exposure
 Hand hygiene
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | cancer of the blood forming tissues (marrow); Affects blood, blood forming tissue of bone marrow, lymph system, spleen Loss of normal cell reproduction
 
 WBC disorders:
 AML-Acute Myelogenous
 ALL-Acute Lymphocytic
 CML-Chronic Myelogenous
 CLL-Chronic Lymphocytic
 
 Hematopoietic stem cell transplant (HSCT)
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Reed Sternberg cells in lymph nodes |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | does not have the Reed Sternberg cells. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Plasma cell myeloma-cancer of the plasma cells in the bone Plasma infiltrates and destroys the bone by forming tumors
 Tumors prevent the bone marrow from producing the cells it needs to
 Tumors put pressure on structures where they are growing
 Anemia-rbc, wbc, platelets are prevented from being produced
 Increases calcium levels in the blood
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | relative increase in immature forms of blood cells. The term actually comes from the fact that, if you go back to a patho book and look at the entire cascade diagram of how blood cells mature, the immature cells are on the left side of the old, standard diagram.If the body is producing and mobilizing a large number of new white cells, then the body is attempting to fight off a very active infection. |  | 
        |  | 
        
        | Term 
 
        | primary immune system disorders |  | Definition 
 
        | impaired immune system; immune system not working correctly |  | 
        |  | 
        
        | Term 
 
        | secondary immune system disorders |  | Definition 
 
        | over-activity of the immune system; hyperresponsive reaction of immune disorders (autoimmune disorders?) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | you do have an immuno  response |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | you do not have an immune system to respond |  | 
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