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Principles of Environmental Science Inquiry and Appications8
Chapter 8: Environmental Health and Toxicology
29
Environmental Studies
Undergraduate 1
10/24/2012

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Term
Disease
Definition
A deleterious change in the body’s condition in response to destabilizing factors, such as nutrition, chemicals, or biological agents. 
Term
Morbidity
Definition
Illness or disease.
Term
Mortality
Definition

Death rate in a population, such as

number of deaths per thousand people per year. 

Term
Environmental Health
Definition
The science of external factors that cause disease, including elements of the natural, social, cultural, and technological worlds in which we live. 
Term
disability-adjusted life years (DALYs)    
Definition
A health measure that assesses the total burden of disease by combining premature deaths and loss of a healthy life that result from illness or disability. 
Term
pathogens   
Definition
Organisms that produce disease in host organisms, disease being an alteration of one or more metabolic functions in response to the presence of the organisms. 
Term
emergent disease    
Definition

A new disease or one that has

been absent for at least 20 years. 

Term
ecological diseases    
Definition
Sudden, wide-spread epidemics among livestock and wild species. 
Term
conservation medicine    
Definition
Attempts to understand how changes we make in our environment threaten our health as well as that of natural communities on which we depend. 
Term
Toxic
Definition
Poisonous
Term
allergens   
Definition
Substances that activate the immune system and cause an allergic response; may not be directly antigenic themselves but may make other materials antigenic. 
Term
Antigens   
Definition
Substances that stimulate the production of, and react with, specific antibodies. 
Term
sick building syndrome    
Definition
A cluster of allergies and other illnesses caused by sensitivity to molds, synthetic chemicals, or other harmful compounds trapped in insufficiently ventilated buildings. 
Term
neurotoxins   
Definition
Toxic substances, such as lead or mercury, that specifically poison nerve cells. 
Term
mutagens   
Definition
Agents, such as chemicals or radiation, that damage or alter genetic material (DNA)
in cells. 
Term
teratogens   
Definition
Chemicals or other factors that specifically cause abnormalities during embryonic growth and development. 
Term
fetal alcohol syndrome    
Definition

A tragic set of permanent physical, mental, and behavioral birth defects that result when mothers drink alcohol during pregnancy. 

Term
carcinogens   
Definition
Substances that cause cancer.    
Term
cancer   
Definition
Invasive, out-of-control cell growth that results in malignant tumors. 
Term
endocrine hormone disrupters    
Definition

Chemicals that interfere with the function of endocrine hormones such as estrogen, testosterone, thyroxine, adrenaline, or cortisone. 

Term
bioaccumulation   
Definition

The selective absorption and

concentration of molecules by cells.

Term
biomagnification   
Definition
Increase in concentration of certain stable chemicals (for example, heavy metals or fat-soluble pesticides) in successively higher trophic levels of a food chain or web. 
Term
persistent organic pollutants (POPs)    
Definition
Chemical compounds that persist in the environment and retain biological activity for a long time. 
Term
synergism   
Definition
When an injury caused by exposure to two environmental factors together is greater than the sum of exposure to each factor individually. 
Term
LD50   
Definition

A chemical dose lethal to 50 percent of a test

population.

Term
acute effects    
Definition
A sudden onset of symptoms or effects of exposure to some factor. 
Term
chronic effects    
Definition

Long-lasting results of exposure to

a toxin; can be a permanent change caused by a single, acute exposure or a continuous, low-level exposure. 

Term
hormesis   
Definition
Nonlinear effects of toxic materials.    
Term
epigenome   
Definition
DNA and its associated proteins and other small molecules that regulate gene function in ways that can affect multiple generations. 
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