Term
| How much does heparin increase the action of antithrombin 3? |
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Definition
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Term
| Which pathway does heparin predominantly effect? How do you measure heparin's effect at the bedside? |
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Definition
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Term
| Why did the USP standardize heaprin dosing in units per ml? |
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Definition
| due to the inconsistent preperations in mg/ml by many different manufactures and the high incidence of bleeding. |
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Term
| Is heparin lipophobic or hydrophobic? |
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Definition
| lipophobic so it does not cross membranes |
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Term
| Give me three instances that will increase heparins half life (what is the half life of heparin anyways?) |
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Definition
| half life is 1-2 hours (2 hours on our final) and it is incresed when we give doses > 100u/kg, temp < 37 C, and if pt has renal/liver disfunction |
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Term
| What are some pathologies that we can treat with heparin? |
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Definition
| DVT, PE, MI, unstable angina, DIC, fetal growth retardation, and with CPB and hemodialysis |
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Term
| WHy is heparin used in cases of fetal growth retardation? |
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Definition
| the growth retardation is often associated with a reduction in placental blood flow (im guessing due to increased clotting) |
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Term
| What complication can heparin cause long term? |
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Definition
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