Term
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Definition
| coexisting relationship between host and microbe |
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Term
| what are some defense systems or barriers to protect against microbial invasion? |
|
Definition
-anatomic barriers
-normal oral flora
-immune system (cellular)
-saliva |
|
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Term
| what are some examples of anatomic barriers? |
|
Definition
-epithelium (skin/intraoral tissue)
-keratin(on hands, soles of feet and oral tissue)
-enamel (hardest tissue of body protects dentin and pulp) |
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Term
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Definition
| fibrous, sulfur containing protein that cannot be penetrated even by gastric acid |
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Term
| what is a site which is very susceptible to invasion due to its oral lack of keratin? |
|
Definition
| junctional epithelium at bottom of sulcus |
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Term
|
Definition
| made of granulomatous tissue which occasionally forms in large lesions that have invaded pulp (like skin layer to protect) |
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Term
|
Definition
| inflammatory response made up of immune cells and fibroblasts. |
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Term
|
Definition
|
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Term
|
Definition
| hardest substance in human body |
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Term
|
Definition
| what happens when hydroxyl group is substituted by flouride |
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Term
|
Definition
| repair of enamel rods after prolonged exposure to an acidic environment. |
|
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Term
|
Definition
| missing ions from teeth are supplied from saliva |
|
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Term
|
Definition
| found in gum and tooth paste contains calcium and phosphate ions |
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Term
| where can one get doses of flouride? |
|
Definition
-short term contact with drinking water
-continual low flouride output from saliva
-bound flouride in plaque released when ph drops to 5.5
-in mature enamel layer after demineralization
-glass ionomers (restorations that release it)
-topical flouride tooth pastes |
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Term
what is the process of normal oral flora?
|
|
Definition
-acquired pellicle (glycoprotiens)
-ealry colonizers s mutans s. sanguis, veillonella(decrease risk of caries
-gram positives
-later colonizers
(normal flora attacks invaders using cellular and humoral immunity) |
|
|
Term
| what are the immunities used in lymph system's normal oral flora? |
|
Definition
-cellular- t cells from thymus
-humoral -b cells from bone marrow/antibodies |
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Term
| in a healthy sulcus the normal oral flora who are gram postitive cocci are? |
|
Definition
| streptococcus gordonii and streptococcus oralis |
|
|
Term
| in a periodontal pocket normal flora are? |
|
Definition
porphyromonas gingivalis
actinocabacillus actinomycetemcomitans |
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Term
|
Definition
| relationship between acid levels (ph) at teh tooth surface and time following consumtion of sugar |
|
|
Term
xerostomia can be very bad for defense mechanisms
true/false
|
|
Definition
|
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Term
|
Definition
lymph nodes, spleen, blood:
they oriniate in bone marrow but become fully functional in thymus. |
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Term
| what oral part consists of lots of b cells? |
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Definition
|
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Term
|
Definition
-yeast that resides in a small quantity of mucosa
it is kept from producing more by the defense mechanisms of saliva, oral flora, and T lymphocytes.
it can be wiped off with gauze |
|
|
Term
| when is saliva least active? |
|
Definition
|
|
Term
| what are some functions of saliva? |
|
Definition
-buffers ph drop
-lubricates
-flushes food debris
-contains antibodies/immunoglobins
-flouride
-antibacterial/ antifungal/antiviral
-remineralizes with calcium/phosphorus |
|
|
Term
| is saliva flow greater when standing or sitting? |
|
Definition
-standing (due to blood pressure changes
|
|
|
Term
| what type of glands are the salivary glands? |
|
Definition
| exocrine glands( leaves gland to bathe oral cavity) |
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Term
|
Definition
|
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Term
|
Definition
| tends to affect elderly women it is an auto immune disease. dry mouth, lots of caries in unusual places |
|
|
Term
| what are the organic components of saliva? |
|
Definition
| amylase, mucins, phosphoproteins, glygoprotiens and immunoglobins. |
|
|
Term
| what helps to control the status of calcium and phosphorus in saliva? |
|
Definition
|
|
Term
|
Definition
pellicle is rich with mucins which help clear carbohydrates from the mouth and protect against caries.
they also help calcium channel in mouth and regulate enzymes like zinc for tissue repair |
|
|
Term
| 5 categories of immunoglobins |
|
Definition
-immunoglobin M (IgM)
-immunoglobin G (IgG
-immunoglobin A (IgA)
-immunoglobin D (IgD)
-immunoglobin E (IgE) |
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Term
|
Definition
| antibodies made of protiens |
|
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Term
|
Definition
B cells that circulate blood
largest of all immunoglobins
1st to appear when there is infection |
|
|
Term
| what is the only immunoglobin that can pass through placenta? |
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Definition
|
|
Term
| what are the 2 subtypes of IgA |
|
Definition
-serum
-secretory(most concern in dentistry)( in saliva) |
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Term
|
Definition
| found on b cells also in very small amounts |
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Term
|
Definition
only in mammals
found in blood, tissue, fluid, exocrine gland secretion
defends against cancer cells responsible for anaphalaxis(systemic allergic reaction can be fatal |
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|
Term
| lack of adequate salive can result in? |
|
Definition
-decreases in:
-electrolytes
-ph
-enzymes
-mucins |
|
|
Term
| what are some products given for those who have xerostomia |
|
Definition
-salogen/pilocarpine
-biotene products |
|
|
Term
| what can cause dry mouth? |
|
Definition
age
prescription drugs
systemic conditions like Sjorens |
|
|
Term
which of the following is not a part of persons natural oral defenses?
a. intact oral epithelium
b.saliva
c. enamel containing flourapetite
d. class II occlusion |
|
Definition
|
|
Term
which oral disease states the hosts defense response is more responsible for tissue destruction than the pathogens themselves?
a. dental caries
b. candida ablicans
c.periodontal disease
d. squamous cell carcinoma |
|
Definition
|
|
Term
| what is the major immunoglobin that dentists are concerned with |
|
Definition
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