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Definition
| the process whereby a medication is moved from the site of application into the body and into the extracellular fluid compartment. |
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Definition
| a mechanism that requires the use of energy to move a substance |
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Definition
| the tendency of a medication to combine with a specific medication receptor. |
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Definition
| a medication or other substance that binds with a specific medication receptor and causes a physiological response. |
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Definition
| the degree to which a medication is bound to tissue or plasma proteins. |
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Definition
| also called metabolism, the the process of changing a medication into a different form, either active or inactive, by the body. |
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Definition
| protective mechanism that selectively allows the entry of specific compounds into the brain. It is an effective boundary between the central nervous system and the peripheral nervous system. |
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Definition
| the process whereby a medication is transported from the site of absorption to the site of action. |
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Term
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Definition
| a measured portion of a med taken at one time. |
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Term
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Definition
| the amount of a medicine or other agent administered for a given case or condition. |
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Definition
| the power of a med to produce a therapeutic effect. |
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Definition
| the process whereby a medication is removed from the body by excretion into the urine, feces, bile, saliva, sweat, breast milk or expired air. |
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Term
| Excretion *or elimination |
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Definition
| the elimination of waste products from the body. Excretion is often used interchangeably with the term elimination |
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Definition
| one of a broad category of simple proteins found in the body. |
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Definition
| the time required for a level of medication in the blood to be reduced by 50 percent of its beginning level. |
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Term
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Definition
| an iron containing compound found within the blood cell that is responsible for the transport and delivery of oxygen to the blood cells. |
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Term
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Definition
| the initial dose of a med given in a sufficient amount to achieve a therapeutic plasma level. |
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Term
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Definition
| the dose of a med necessary to maintain a constant therapeutic plasma level. |
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Definition
| Biochemical and physiological events when medications reach their targeted tissues. |
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Term
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Definition
| the sum total of all physical and chemical changes that occur within the body. Also used interchangeable with the term biotransformation. |
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Term
| Minimum effective concentration |
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Definition
| the minimum amount of med needed in the bloodstream to cause the desired therapeutic effect. |
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Term
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Definition
| the time interval between the administration of a medication and the first sign of its onset. Onset is influenced by the physical and chem properties and also by its route. |
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Term
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Definition
| a mechanism of transport that does not require the use of energy to move a substance. |
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Term
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Definition
| a scientific method of expressing the acidity or alkalinity of a solution, which is the logarithm of the hydrogen ion concentration divided by 1. The higher the pH, the more alkaline the solution; the lower the pH the more acidic the solution. |
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Definition
| the study of a medication's action in the body. |
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Definition
| the study of how medications enter the body, reach their site of action and eventually are eliminated. |
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Term
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Definition
| the tendency of a medication to dissolve |
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Definition
| an index of the medication's safety profile, which is determined by calculating the difference between the medications therapeutic threshold and toxic level. It's typically determined in a lab. |
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Term
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Definition
| the minimum amount of medication needed in the blood stream to cause the therapeutic effect. |
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Term
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Definition
| the plasma level at which severe adverse reactions are expected or likely. |
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