Term
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Definition
| extent to which a drug retains the same properties and characteristics that it possessed at the time of its manufacture |
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Term
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Definition
-formulation/compounding
-mixing
-packaging/repackaging
-storage |
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Term
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Definition
-chemical
-physical
-microbiologic
-therapeutic
-toxilogical |
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Term
| chemical stability can be affected by |
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Definition
-chemical structure
-drug-excipient reactions
-environmental factors
-formulation factors |
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Term
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Definition
-loss of active ingredient/potency due to decomposition
-decomposition products can be harmful
-physical changes can decrease the efficacy |
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Term
| chemical stability important for |
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Definition
-selecting proper excipients
-selecting processing methods
-selecting storage conditions
-selecting proper packaging/containers for dispensing
-anticipating interactions when mixing drugs and dosage forms |
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