Term
| What the functions of progesterone? |
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Definition
| promotes breast development, regulates menstrual cycle, prevents premature labor contractions |
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Term
| Functions of testosterone? |
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Definition
| maturation of male sex organs, secondary sexual characteristics, metabolic effects on muscle |
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Term
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Definition
| regulates sperm and egg production. |
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Term
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Definition
| Triggers ovulation, Promotes the release of estrogen and progesterone in the overy, Regulates the production of testosterone. |
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Term
| How do estrogen-progestin oral contraceptives act? |
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Definition
| They stop secretion of FHS and LH by the pituatary gland (NEGATIVE FEEDBACK). They make the lining of the uterus less favorable to receive the embryo. |
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Term
| Adverse effects of oral contraceptives. |
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Definition
| Increase risk of blood clots especially in smokers and over 35 yoa. Breakthrough bleeding, Unusual breast lumps. |
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Term
| What medications tend to decrease the effectiveness of oral contraceptives? |
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Definition
| antibiotics, antifungals, Rifampin (for TB), barbituates, and anticonvulsives. |
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Term
| How do progestin-only oral contraceptives work? |
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Definition
| They cause a thick mucus at the entrance of the uterus that sperm cannot penetrate. They are less effective than estrogen-progestin combinations. There is a higher incidence of menstrual irregularities. |
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Term
| Estrogen Replacement Therapy is prescribed to relieve? |
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Definition
| Menopausal symptomes, osteoporotic bone fractures. |
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Term
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Definition
| coronary artery disease, stroke, and venous thromboembolism. |
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Term
| Uses of estrogen in cancer therapy? |
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Definition
| To tx prostate cancer by suppressing androgen secretion. It is also used with other agents along side chemo. |
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Term
| Progestins are used to treat what cancer? |
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Definition
| endometrial cancer (only used pallatively) |
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Term
| Androgens are used for what? |
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Definition
| certain breast cancers, promote normal gonadal development. |
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Term
| What are some uses for progestins? |
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Definition
| dysfunctional uterine bleeding, tx of metastatic endometrial carcinoma (used palliatively). |
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Term
| Oxytocin uses what feedback system? |
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Definition
| Positive feedback (as a fetus grows) |
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Term
| Why not to take nitrates with ED meds? |
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Definition
| ED meds (like Viagra) cause vasodialation which decreases BP. |
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Term
| How does BPH drugs (like Flomax) relieve BPH? |
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Definition
| Alpha1-adrenergic blockers (like Flomax) relax smooth muscle in the prostate gland, easing urinary obstruction. These can cause impotence. These can also be used for BP meds. |
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