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pleural effusion clinical
RPM II
33
Medical
Graduate
05/28/2010

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Term
what is the blood supply to the parietal pleura?
Definition
systemic capillaries such as intercostal arteries and the superior phrenic artery
Term
what is the blood supply to the visceral pleura?
Definition
probably systemic capillaries such as the bronchial artery
Term
what is the lymphatic supply to the parietal pleura?
Definition
lymphatic vessels in communication w/the pleural space by means of stomas
Term
what is the lymphatic supply to the visceral pleura?
Definition
there are abundant lymphatic vessels BUT pleural fluids do not enter the lymphatics in the visceral pleura
Term
does the visceral pleura have pain fibers?
Definition
no
Term
what is the innervation to the parietal pleura?
Definition
*costal pleura: *intercostal nerves (when stimulated, pain is perceived in the adjacent chest wall). *diaphragmatic pleura: *phrenic nerve (when stimulated, pain is perceived in the ipsilateral shoulder (which is why after laproscopy, gas needs to be cleared out of pts abdomens, b/c the irritation from it can refer to the shoulder)
Term
what structures contribute to the pleural fluid?
Definition
CLIP: capillaries, lymphatics, interstitial, peritoneal cavity
Term
what is the general direction of fluid movement across the parietal pleura?
Definition
an interplay of hydrostatic and oncotic pressure gradients favor fluid migration from the parietal pleura *into the pleural space
Term
what is the net fluid movement across the visceral pleura?
Definition
close to zero (driving force is parietal pleura)
Term
what can cause thoracic duct interruption?
Definition
trauma and malignancies (esp w/breast+lung lymphomas)
Term
how strong is the barrier to movement of fluid across the visceral pleura to the pleural space?
Definition
the barrier is weak, therefore when the *subpleural interstitial pressure increases, fluid will transverse the visceral pleura into the pleural space
Term
what are causes of fluid formation in the peritoneal cavity?
Definition
peritoneal dialysis and ascities
Term
what are reasons for increased pleural fluid accumulation?
Definition
increased interstitial fluid (LV failure, pneumonia, PE), increased intravascular pressures (RV or LV failure, SVC syndrome), decreased pleural pressure (atelectasis - collapse = negative pressure), increased peritoneal fluid (ascites, peritoneal dialysis), disruption of the thoracic duct, and increased pleural protein level (caused by increased capillary permeability)
Term
what are some causes of decreased fluid absorption that lead to pleural fluid accumulation?
Definition
lymphatic obstruction and elevation of systemic vascular pressures (RV failure or SVC syndrome)
Term
what is one way of differentiating pleural effusion and pneumonia?
Definition
pleural effusions have more of a meniscus shape to them
Term
how can you determine if there is loculated pleural effusion w/x ray?
Definition
lay the pt down in the lateral decubitus position
Term
can unilateral pleural effusion cause a mediastinal shift?
Definition
yes, pleural effusions can push the mediastinum to one side
Term
what can fix the mediastinum in place when it should be shifting due to pleural effusion pressure?
Definition
cancer, inflammation, some fungal diseases (histo can cause scarring)
Term
what is subpulmonic effusion?
Definition
NOT subdiaphragmatic, subpulmonic effusion is between the lungs and the diaphragm. it usually will cause a lateral displacement of the diaphragm. it is more visible w/a gastric air bubble
Term
what is a loculated effusion?
Definition
a pocket of fluid trapped in the lungs
Term
should there ever be a straight line in the chest?
Definition
no, this is indicative of free air in the lungs - as seen w/a hydropneumothorax
Term
how do pts w/pleural effusion present?
Definition
pain (if in *chest wall, suggests *localized parietal pleural involvement, if *shoulder involved, suggests ipsilateral *diaphragmatic area of parietal pleural), non productive cough (secondary to lung compression), and dyspnea
Term
if fluid is removed from the lungs, does the equivalent level of air volume return back?
Definition
no - thoracentesis of a large volume of fluid results in a much smaller than anticipated improvement in lung volume (b/c the body modifies V/Q matching w/compression)
Term
can ventricular filling be decreased w/large effusions?
Definition
yes
Term
how will pts with pneumothorax appear on physical examination?
Definition
the affected hemithorax will be larger, the intercostal spaces may be convex, percussion may be dull (not as reliable as fremitus), and tactile fremitus will be attenuated/absent (due to separation of the lung from the chest wall bu fluid) *consolidation (pneumonia) will increase fremitus*
Term
what is egophony?
Definition
long e to a short a sound over the effusion
Term
what causes transudative effusions? exudative?
Definition
CHF, cirrhosis, myxedema, and nephrotic syndrome (4 major organ systems). exudative effusions are caused by everything else.
Term
what is light's criteria?
Definition
a pleural effusion is likely transudative if at least one of the following exists:

1. the ratio of pleural fluid protein to serum protein is less than 0.5
2. the ratio of pleural fluid LDH and serum LDH is less than 0.6
3. pleural fluid LDH is less than 0.7 times the normal upper limit for serum
Term
when is a RBC count higher than 100,000 seen?
Definition
tumor, infarction, trauma (TIT)
Term
neutrophils reflect what? lymphocytes?
Definition
neutrophils reflect acuteness, lymphocytes reflect chronicity
Term
what should you think of with an eosinophilic pleural effusion in an older shipyard worker?
Definition
asbestos related effusions
Term
can air (pneumothorax) alone cause eosinophilia in the lungs?
Definition
yes
Term
what test will differentiate pneumonias that require a chest tube asap?
Definition
pneumonias with a low pH (called a complicated pneumonia)
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