| Term 
 | Definition 
 
        | 1. replacement therapy in hormone deficiency 2. diagnostic aids to determine hypo-hyper function of specific hormonal function
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        | Term 
 | Definition 
 
        | 1. used to diagnose adrenal dysfunction and imitate the function of ACTH in body 2.  when cosyntropin is administered and adrenal glands fail to increase serum cortisol levels, the pt is diagnosed with primary adrenocortical insufficiency or Addison's disease
 |  | 
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        | Term 
 
        | When Cosyntropin is administered and adrenal glands fail to increase serum cortisol levels the pt is diagnosed with |  | Definition 
 
        | primary adrenocortical insufficiency or Addison's disease |  | 
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        | Term 
 
        | Addison's disease is treated with |  | Definition 
 | 
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        | Term 
 
        | Cortisol has ________ effects and promotes _________________ which can result in ________ and ______________. |  | Definition 
 
        | antiinflammatory; renal retention of sodium; edema; hypertension |  | 
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        | Term 
 
        | When administering octreotide (Sandostatin) to a patient, it is most important for the nurse to assess |  | Definition 
 
        | blood sugar - ocreotide may cause alterations in blood glucose levels; closely monitor blood glucose during drug therapy |  | 
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        | Term 
 
        | Nursing Implications:  - ACTH 
 Cosyntropin/Cortrosyn
 |  | Definition 
 
        | 1. IM, SC, IV forms, gel and repository forms 2. follow directions carefully for administration
 3. maintain adequate hydration
 4. decrease sodium and potassium intake
 5. avoid vaccinations during drug therapy
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        | Term 
 
        | Nursing Implications - ACTH 
 Cosyntropin/Cortrosyn - therapeutic responses
 |  | Definition 
 
        | 1. Cosyntropin should eliminate pain associated with inflammation and produce increased comfort and muscle strength in pts with multiple sclerosis |  | 
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        | Term 
 
        | Somatropin/Somatrem - indications |  | Definition 
 
        | 1. recombinantly made growth hormone (GH) 2. stimulate skeletal muscle growth in pts w/ deficient GH, such as hypopituitary dwarfism
 3. should increase growth in children - keep journal
 |  | 
        |  | 
        
        | Term 
 
        | Ten year old N. has begun somatrem therapy.  Wants to skip follow-up. |  | Definition 
 
        | She should keep to monitor therapeutic effects and adverse effects.  Adverse effects could include altered glucose levels, thyroid, and bone problems. |  | 
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        | Term 
 | Definition 
 
        | 1. reduces diarrhea caused by carcinoid tumors that secrete (VIP) vasoactive intestinal polypeptide 2. reduces flushing and potential life-threatening hypotension that may occur with a carcinoid crisis.
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        | Term 
 
        | Nursing Implications: octreotide (Sandostatin)
 |  | Definition 
 
        | 1. may impair gallbladder function - report abdominal pain 2. use with caution in pts with renal impairment and all types of diabetes
 3. monitor glucose levels in pts with diabetes, and even in those who do not have diabetes
 4. can be given IV, IM, or SC
 5. should reduce symptoms of carcinoid crisis
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        | Term 
 
        | Vasopressin and desmopressin |  | Definition 
 
        | 1. used to treat diabetes insipidus 2. vasopressin: powerful vasoconstrictor used for hypotensive emergencies, GI bleeding, and pulseless cardiac arrest
 3. Desmopressin: Used for dose-dependent treatment of blood disorders; also used for nocturnal enuresis
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        | Term 
 
        | Desmopressin/vasopressin - therapeutic responses |  | Definition 
 
        | 1. reduce severe thirst 2. decrease urinary output
 |  | 
        |  | 
        
        | Term 
 
        | Nursing Implications: Desmopressin/Vasopressin
 
 Interactions
 |  | Definition 
 
        | 1. Lithium 2. alcohol
 3. democlocycline
 these reduce desmopressin effects
 |  | 
        |  | 
        
        | Term 
 
        | desmopressin/vasopressin 
 pt. teaching
 |  | Definition 
 
        | provide specific instructions for nasal spray forms of vasopressin |  | 
        |  | 
        
        | Term 
 
        | A pt who is on vasopressin therapy calls to say he is not improving as expected.  Further questioning reveals he has not stopped drinking beer. |  | Definition 
 
        | Pt should be told to stop drinking because it reduces the effect of vasopressin |  | 
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        | Term 
 
        | Nursing Implications Pituitary drugs
 |  | Definition 
 
        | 1. Obtain thorough nursing assessment and medication history 2. assess for contraindications specific to each drug
 3. assess medication history for possible interactions
 |  | 
        |  | 
        
        | Term 
 
        | Nuring Implications II Pituitary drugs
 |  | Definition 
 
        | 1. rotate injection sites 2. do not discontinue drugs abruptly
 3. do not take OTC products w/o checking with provider
 4. adverse effects specific to individual drug
 |  | 
        |  | 
        
        | Term 
 
        | Follicle stimulating hormone (FSH) |  | Definition 
 | 
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        | Term 
 | Definition 
 | 
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        | Term 
 
        | adrenocorticotropic hormone |  | Definition 
 | 
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        | Term 
 | Definition 
 | 
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        | Term 
 | Definition 
 | 
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        | Term 
 
        | A pt will be receiving somatropin.  The nurse expects the pt has which disorder? |  | Definition 
 
        | Hypopituitary dwarfism 
 Somatropin is human growth hormone that is used in the treatment of dwarfism.
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | the diagnosis of adrenocortical insufficiency |  | 
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        | Term 
 | Definition 
 | 
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        | Term 
 
        | vasopressin is indicated for |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | 1. indicated in treatment of growth failure due to inadequate growth hormone secretion 2. used for pts with HIV infection with wasting or cachexia in conjunction with antiviral therapy
 3. Preg. category B or C - depending on manufacturer
 4. contraindicated in pts with  closed growth plates, pts with tumors, pts with acute illness
 5. adverse effects: headache, injection site reactions, muscle pain, hypoglycemia or hyper glycemia.
 6. do not shake product.
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | 1. useful in alleviating certain symptoms of carcinoid tumors stemming from the secretions of VIP 2. symptoms include severe diarrhea, flushing, potentially life-threatening hypotension associated with a carcinoid crisis
 3. treatment of esophageal varices
 4. adverse effects: may impair gallbladder function and needs to be used with caution in pts with renal impairment.  It may affect glucose regulation and severe hypoglycemia may occur in type I diatetic pts. causes hyperglycemia in type II.
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | 1. used to prevent or control polydipsia (thirst), polyuria, and dehydration in pts with diabetes insipidus caused by deficiency of ADH. 2. also used to control various types of bleeding (GI hemorrhage), and in pulseless arrest and vasodilatory shock.
 3. contraindicated in pts with known hypersensitivity
 4. Preg. category C
 5. administer w/caution in pts w/ seizure disorders, asthma, cardiovascular disease, renal disease
 6. IV infiltration may lead to severe vasoconstriction and localized tissue necrosis...watch for any signs of infiltration and use central venous access device when possible
 7. available as a nasal spray or injection for IM or IV use
 8. when used to treat septic shock, it is given by continuous IV infusion
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