Term
| characterized by excessive output of dilute urine |
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Definition
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Term
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Definition
| nephrogenic, neurogenic or dipsogenic |
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Term
| inherited defect in which the renal tubules of the kidney do not respond to ADH, resulting in inadequate water reabsorption by the kidneys |
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Definition
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Term
| in nephrogenic DI adh is produced in sufficient amounts but the ____ do not respond to it appropriately |
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Definition
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Term
| some cases of nephrogenic DI are caused by drugs like |
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Definition
| lithium carvonate (eskalith-CR), democlocycline (declomycin) |
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Term
| lithium carvonate and democlocycline inhibits the kidneys response to |
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Definition
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Term
| a defect in either the production or the secretion of ADH |
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Definition
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Term
| neurogenic DI can result from |
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Definition
| hypothalamic tumors, head trauma, infection, surgical procedures or metastatic tumors originating in the lung or breast |
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Term
| Neurogenic DI can also be triggered by |
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Definition
| CVA, aneurysm, intracranial hemorrhage |
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Term
| a disorder of thirst stimulation |
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Definition
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Term
| other factors that may be associated with dipsogenic DI |
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Definition
| habitual excessive water intake, and psychiatric conditions |
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Term
| adh deficiency or an inability of the kidneys to respond to ADH results in the excretion of large volumes of very dilute urine |
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Definition
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Term
| electrolyte imbalances contribute to circulatory collapse by causing |
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Definition
| dysrythmias and impired contractility of the heart |
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Term
| common signs and symptoms of DI are |
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Definition
| massive diuresis, dehydration and thirst |
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Term
| the diagnosis DI is made primarily on the basis of |
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Definition
| health history, physical examination and laboratory findings |
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Term
| the loss of free water is apparent in laboratory studies of |
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Definition
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Term
| an initial diagnosis of DI is mad based on a 24-hour urine output greater than |
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Definition
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Term
| Pts with DI can excrete up to |
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Definition
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Term
| For the water deprivation test, water is withheld for 8 to 16 hours during which the |
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Definition
| BP, weight and urine osmolality are measured each hour |
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Term
| water deprivation test is stopped when |
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Definition
| osmolalities stabilize, the pt loses 5% of his or her body weight, or the pt develops orthostatic hypotension |
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Term
| For management of DI ______ are often required to maintain adequate BP |
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Definition
| Intravenous fluid volume replacement |
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Term
| the most common hormone replacement drug from neurogenic DI is |
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Definition
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Term
| The administration of ADH does not help with nephrogenic DI because the kidneys ____ respond to the hormones |
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Definition
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Term
| sodium intake may be restricted and _______ prescribed for nephrogenic DI |
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Definition
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Term
| drugs that may be used to treat DI |
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Definition
| chlorpropamide, clofibrate, carbamazepine, indomethacin |
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