Term
| what nuclei comprise the basal ganglia |
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Definition
| caudate, putamen, GP, substantia nigra, STN, amygdala, claustrum |
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Term
| what do CAG repeats do to striatal cells? |
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Definition
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Definition
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Term
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Definition
| extrapyramidal motor system |
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Term
| fxn of ventral striatal basal ganglia system? |
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Definition
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Term
| components of the ventral striatal basal ganglia system? |
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Definition
| n. accumbens (ventral striatum), ventral palladium, ventral tegmental area |
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Term
| what projects from the VTA and where does it go? |
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Definition
| mesolimbic DA to ventral striatum, mesocortical DA to frontal cortex |
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Term
| effect of "direct" path on movement? |
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Definition
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Term
| effect of "indirect path on movement? |
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Definition
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Term
| DAR in the direct pathway? |
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Definition
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Term
| DAR in the indirect pathyway? |
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Definition
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Term
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Definition
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Term
| GP NT in the stop pathway? |
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Definition
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Term
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Definition
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Term
| two routes from GP to thalamus |
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Definition
| lenticular fasciculus, ansa lenticularis |
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Term
| effect of large lesion in the STN? |
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Definition
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Term
| striatal element of the dorsal striatal system? |
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Definition
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Term
| striatal element of the ventral striatal system? |
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Definition
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Term
| pallidal element of the dorsal striatal system? |
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Definition
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Term
| pallidal element of the ventral striatal system? |
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Definition
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Term
| cortical input of the dorsal striatal system? |
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Definition
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Term
| cortical input of the ventral striatal system? |
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Definition
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Term
| thalamic target of the dorsal striatal system? |
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Definition
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Term
| thalamic target of the ventral striatal system? |
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Definition
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Term
| cortical target of the dorsal striatal system? |
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Definition
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Term
| cortical target of the ventral striatal system? |
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Definition
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Term
| what is the D2 receptor blocker used to treat schizo? |
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Definition
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Term
| what is the long term SE of the haldol? |
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Definition
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Term
| what structure is sometimes submitted to DBS to treat PD? |
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Definition
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Term
| what is the anatomy of the bradykinesia in PD? |
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Definition
| inc inhib output of GPm to the VL thalamic motor nucleus impairs stim of motor cortex |
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Term
| what is the anatomy of hyperkinesic disorders in the basal ganglia? |
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Definition
| dec inhib output of GPm to VL enhances stim of motor cortex |
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Term
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Definition
| resting tremor, rigid, bradykin, postural problems |
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Term
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Definition
| masked fascies, hypophonic speech, stooped posture with shuffling/propulsive gait, micrographia, autonomic disfxn |
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Term
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Definition
| eosinophilic, intraneuronal cytoplasmic inclusions |
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Term
| why give anticholinergics to PD pts? |
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Definition
| counteract 'unnopposed' cholinergic system |
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Term
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Definition
| hallucination, psychosis,chorea, dystonia, nv, hyperkinesia |
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Term
| two surgical procedures for PD |
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Definition
| pallidotomy (GPm), STN stim |
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Definition
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