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Physiology
Endocrine System: Glands and hormone actions
35
Biology
Undergraduate 2
09/29/2011

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Term
Describe the hypothalamus.
Definition
A region at the base of the brain that regulates autonomic functions secretes hormones that which mostly regulate secretory activity of the pituitary gland.
Term
What 2 ways does the hypothalamus control secretions of the pituitary gland?
Definition
-Releasing hormones
-Inhibiting hormones
Term
What are the 7 hormones of the anterior pituitary gland?
Definition
-Growth Hormone (GH)
-Adrenocorticotrophic hormone (ACTH)
-Thyroid stimulating hormone (TSH)
-Prolactin
-Follicle stimulating hormone (FSH)
-Luteinizing hormone (LH)
-Melanocyte stimulating hormone (MSH)
Term
Describe the function of growth hormone.
Definition
Essential for growth; stimulates bone and soft tissue growth; regulates protein, lipid and carbohydrate metabolism
Term
Describe the function of Adrenocorticotropic hormone (ACTH)
Definition
Stimulates glucocorticoid secretion by the adrenal cortex
Term
Describe the function of thyroid stimulating hormone (TSH).
Definition
Stimulates secretion of thyroid hormones by the thyroid gland.
Term
Describe the function of prolactin.
Definition
Stimulates development of breasts and milk secretion by the mammary glands.
Term
Describe the function of follicle stimulating hormone (FSH) in males and females.
Definition
Females- Stimulates growth and development of ovarian follicles, estrogen secretion.
Males- Stimulates sperm production by the testis
Term
Describe the function of luteinizing hormone (LH) in males and females.
Definition

Females- Stimulates ovulation and secretion of estrogen and progesterone

Males- Stimulates testosterone secretion by the testis

Term
What are the 2 hormones secreted by the posterior pituitary gland?
Definition
-Antidiuretic hormone (ADH, or vasopressin)
-Oxytocin
Term
Describe the function of antidiuretic hormone (ADH or vasopressin).
Definition
Decreases urine output by the kidneys; promotes constriction of blood vessels (arterioles)
Term
Describe the function of oxytocin in males and females.
Definition
Females- Stimulates uterine contractions and milk ejection by mammary glands
Males- Function is unknown.
Term
What 3 ways is the endocrine system controlled by a negative feedback system.
Definition
-Regulation of hypothalamus corticotropic releasing hormone(CRH).
-Thyroid hormones
-Metabolites or Ions
Term
Describe the negative feedback loop by the regulation of Corticotropic releasing hormone (CRH).
Definition
Hypothalamus  (releases) -> CRH which causes the -> anterior pituitary to release ACTH which -> causes the adrenal cortex to release cortisol which -> causes a target cell response.
Term
Describe the negative feedback loop by thyroid hormones.
Definition
Hypothalamus -> (releases) TRH hormone which -> causes the anterior pituitary to secrete TSH  which -> causes the thyroid gland to secret thyroid hormone which -> causes a target cell response.
Term
Describe the negative feedback loop by metabolites or ions.
Definition

Metabolites :

High blood glucose is monitored by beta cells of pancreas. High blood glucose causes -> beta cells of pancreas to release insulin which -> causes the cells to absorb glucose which -> lowers blood glucose levels

Ions:

High Blood potassium levels are monitored by the adrenal cortex. High blood potassium causes -> adrenal cortex to secrete aldosterone which -> causes the kidneys to excrete potassium out of the body which -> causes the  blood potassium levels to drop

Term
Describe the function of the pineal gland.
Definition
Releases melatonin which regulates biological rhythms according to day-night cycles.
Term
Describe the function of the thymus gland.
Definition
Releases thymosin which stimulates proliferation and function of T lymphocytes.
Term
Describe the function of the thyroid gland.
Definition
Secretes thyroid hormones and calcitonin.
Thyroid hormones- Increase basal metabolic rate
Calcitonin- Promotes calcium deposition in bone and lowers blood calcium levels.
Term
Describe the function of C cells.
Definition
Cells located in the thyroid gland that secrete calcitonin.
Term
Describe the function of adrenal cortex of the adrenal glands.
Definition
Releases mineralcorticoids (aldosterone)-> stiumulates sodium reabsorption and potassium secretion by kidney tubules, glucocorticoids (cortisol, corticosterone)-> raise blood glucose levels and androgens (dehydroepiandrosterone, androstenedione) ->promotes sex drive.
Term
Describe the function of the adrenal medulla of the adrenal glands.
Definition
Releases epinephrine which stimulates fight or flight response.
Term
Describe the function of the pancreas.
Definition
Releases insulin -> lowers blood glucose levels, glucagon -> raises blood glucose levels and somatostatin -> inhibits secretion of pancreatic hormones.
Term
Describe the function the male gonads (testes).
Definition
Releases androgens (testosterone, androstenedione) -> secondary sex characteristics.
Term
Describe the function of female gonads (ovaries) in non-pregnancy state.
Definition
Releases estrogens (estradiol)-> development of secondary sex characteristics and progestins (progesterone) -> prepares uterus for pregnancy.
Term
Describe the function of the placenta (female gonads during pregnancy).
Definition
Releases chorionic gonadotropin, estrogens, progesterone which maintains corpus luteum..
Term
What 3 things control hormone secretions.
Definition
Neural signals, humoral signals (works on a negative feedback loop) and circulating levels of hormones(works on a negative feedback loop).
Term
Describe how neural signals controls hormone secretions.
Definition
Hypothalamus can be stimulated by upper levels of neural control such as response to stress.
Term
Describe how humoral signals control hormone secretions.
Definition
Hypothalamus/pituitary monitor circulating levels of hormone and make appropriate adjustments if levels change.
Specific glands monitor circulating levels of ions and metabolites and make appropriate adjustments if levels change.
Term
What are the 4 hormone interactions?
Definition
Antagonism, Additive, Synergism and Permissiveness.
Term
Define antagonism.
Definition
When one hormone opposes the actions of another hormone.
Term
Define additive.
Definition
Indicates that the effect of 2 hormones is simply the sum of the effects of each hormone.
Term
Define synergism.
Definition
Effects of 2 hormones favor each other but the net effect exceeds the sum of individual effects.
Term
Define permissiveness.
Definition
1 hormone is needed for another hormone to exert its actions.
Term
Describe function of melanocyte stimulating hormone (MSH).
Definition
Increases melanin secretion in epidermis.
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