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Physiology
N/A
37
Health Care
Graduate
02/27/2013

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Term
Autonomic Nervous System
Definition
Afferent/Efferent Nerves: Primary preganglionic neuron (brainstem or spinal cord); axon to synapse on postganglionic neuron
Two antagonistic subdivisions: Parasympathetic, Sympathetic
Term
Parasympathetic Nervous Symstem
Definition
Preganglionic fibers end on short postsynaptic neurons
Vagus Nerve (CN X)(75% of nerve fibers)
First, second*, third* and fourth sacral nerves
Term
Sympathetic Nervous System
Definition
Preganglionic nerve fibers short
End on postsynaptic neurons with long fibers T1 - L 3,4

Pass from spinal cord into paravertebral sympathetic ganglion chains
Stellate ganglia (cranial)
Adrenal medulla
Term
Neurotransmitters
Definition
Acetylcholine (cholinergic)
Preganglionic fibers (para and sympathetic ns) and postganglionic parasympathetic
Norepinephrine (adrengeric)
Postganglionic sympathetic ns
Are exceptions (few blood vessels, sweat glands and piloerector Mm)
Term
Neurotransmitter Receptors
Definition
Cholenergic
Muscarinic
Post-synaptic and effector
Nicotinic
Pre/post synaptic neurons in ANS
Adrenergic
Alpha
Beta
Dopaminergic
Receptors in adrenal gland, blood vessels, heart
Term
ANS Control of Cardiovascular Phys
Definition
SA Node
Term
Respiration
Definition
Pulmonary ventilation (inspiration, expiration):breathing, exchange O2 (active, exchange CO2 (passive), control blood acidity, oral communication
Term
Lung Pressure At Rest
Definition
Lung: 760 mmHg= 760 mmHg :Atmosphere
Term
Lung Pressure During Inspiration
Definition
Lung:758mmHg < 760mmHg:Atmosphere
Term
Lung Pressure During Expiration
Definition
Lung: 763mmHg > 760mmHg : Atmosphere
Term
Tidal Volume (VT)
Definition
Volume of air normally exhaled/inhaled per breath
Term
Inspiratory reserve volume (IRV)
Definition
Additional volume taken in
Term
Expiratory reserve volume (ERV)
Definition
Additional volume let out
Term
Residual volume (RV)
Definition
Volume of air that remains in the lungs after a forceful expiratory effort
Term
Inspiratory Capacity (IC)
Definition
The sum of the tidal and inspiratory reserve volumes
Maximum amount of air that can be inhaled after a normal tidal exhalation
Term
Functional Residual Capacity (FRC)
Definition
The sum of expiratory reserve and residual volumes
The amount of air remaining in the lungs at the end of a normal tidal exhalation
Represents the point at which the forces tneding to collapse the lungs are balances against foreces tending to expand the chest wall
Term
Vital Capacity (VC)
Definition
Sum of inspiratory reserve tidal, and expiratory reseerve volumes
The maximum amount of air that can be exhaled following a maximum inhalation
Term
Total Lung Capacity (TLC)
Definition
The maximum volume to which the lungs can be expanded
Sum of all the pulmonary volumes
Term
Minute ventillation (VE)
Definition
The product of tidal volume and respiratory rate
Term
Normal Pulmonary Measurements
Definition
FEV: 4.0
FCV: 5.0
80%
Term
Obstructive Pulmonary Measurements
Definition
FEV: 1.3
FVC: 3.1
42%
Term
Restrictive Pulmonary Measurements
Definition
FEV: 2.8
FVC: 3.1
90%
Term
O2 unloads from hemoglobin with changes in:
Definition
Temperature
Cardbon dioxide concentration
Hydrogen ion concentration
Term
Rate of unloading O2 depends on the demands of:
Definition
Mitochondria
Increases shift curve to right: Exercise
Decreases shift curve to left: Hyperventilation
Term
Functionally Normal pH
Definition
7.4
Term
pH changes 1 unit (6.0 to 7.0) and H+ increases:
Definition
10x
Term
Carbonic Acid-Bicarbonate buffering
Definition
Lungs: Blow off or hold CO2
Kidneys: Absorb or regenerate bicarbonate
Term
20:1 ratio (bicarbonate: carbonic acid)
Definition
Normal bicarb 24mEq/L: carbonic acid 1.2mEq/L
pH of 7.4
Term
Compensation
Definition
Body’s adjustments to pH changes
Term
Correction
Definition
Values for bicarbonate and carbonic acid return to normal
Term
Respiratory Center
Definition
control of motor neurons
Term
Regulatory Centers
Definition
Medullary inspiratory center
Medullary expiratory center
Establish rate and depth of breathing
Term
What area of the brain can override respiratory/regulatory centers?
Definition
Cortex (active expiration)
Term
Medullary Chemoreceptors
Definition
Sensitive to changes in [H+]: Cerebrospinal fluid
BBB impermeable to H+: CO2 can diffuse( React to form H+)
Stimulates inspiratory center: Increase rate and depth,Clearance
Term
Peripheral chemoreceptors
Definition
Sensitive to changes in:
PO2 and PCO2**
H+
Arch of aorta and bi-carotid arteries
Term
Lung receptors
Definition
Acute stretch of alveoli
Safety mechanism- decrease duration of
inspiration
Term
Mechanical receptors
Definition
Sense movement in skeletal muscle
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