Term
| What is the total Renal Blood Flow to the kidneys? |
|
Definition
|
|
Term
|
Definition
| A measure of the filtration rate of the all the glomeruli of the kidneys |
|
|
Term
| What is the Filtration Fraction (FF)? |
|
Definition
It is a measure of all the plasma filtered by the kidneys. Divide GFR/Total Renal plasma flow
GFR/RPF = FF |
|
|
Term
| How do you measure Renal Plasma Flow from Renal Blood Flow? |
|
Definition
| RPF = RBF x (1-hematocrit) |
|
|
Term
| What is the difference between ultrafiltrate and plasma? |
|
Definition
| Not much. Ultrafiltrate lacks some of the plasma proteins found in plasma. |
|
|
Term
|
Definition
| It is the filtration coefficient. It is determined by the surface area of the glomerular capillaries times the relative permeability of the capillary membrane to water. It determines how much solvent can move through the glomerular filtration barrier in relation to the osmotic and hydrostatic forces that prevail |
|
|
Term
|
Definition
| It is the reflection coefficient. It is normally = 1 b/c proteins are impermeable |
|
|
Term
| Does the permeability layer have negatively or positively charged particles? |
|
Definition
| negatively. Just think about Na. It's positive and has the easiest time getting through. |
|
|
Term
| What are the factors influencing the GFR? |
|
Definition
Major factor - hydrostatic pressure
Decrease in surface area - decrease in GFR
Humoral factors that decrease permeability
Degree of hydration of basement membrane
pH |
|
|
Term
| How is clearance measured? |
|
Definition
| Clearance of X = Urine Conc. of X times Urine flow rate/ all divided by plasma concentration of X |
|
|
