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Physiology psych exam2
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111
Physiology
Undergraduate 4
11/19/2014

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Cards

Term

Lichtheim's Model

Brocas Area

Definition
which is responsible for speech output
Term

Lichtheims model

Wernickes area

Definition
process the sound images of words and this information is then fed forward through a nerve fiber trace, the arcuate fasciculus
Term

Lichtheims Models

Concept Center

Definition
the input from wernickes ares is disconnected causes transcoritical sensory aphasia/ the output from the concet center cant reach brocas are causes transcortical motor aphasia
Term
Brocas Aphasia
Definition
lesion to a specific region of the left hemisphere causes a loss of fluent speech even though the persons speech comprehension is relatively spared
Term
telegraphic speech
Definition
sentences do not fit a standard structure, but seem more like a telegram or text message, words produced tend to be only content words such as nouns and verbs/ no endings example ing
Term
wernickes aphasia
Definition
disrupted speech comprehension along with fluent but nonsensical speech output
Term
word salad
Definition
their output is a jumble of words
Term
paraphasias
Definition
hard to comprehend not only because the words are combined in a way that makes little sense but also because of errors in producing specific words
Term
neologisms
Definition
made up words that follow the rules for combining sounds in the language yet are not real words
Term

conduction aphasia:

Inability to repeat

damage to what..

Definition

Langauge comprehension and speech production would be intact, yet the person would not be able to repeat what was just heard becuase sound images recieved by wernickes area could not be conducted forward to brocas area to be produced

Often make phonemic paraphasias may substitute or omit words or may be unable to say anything

Large nerve fiber tract known as the acruate fasciculus along with sorrounding tissue

Term
Transcoritcal sensory aphasias
Definition
symptoms similar to those of patients with wernickes, except that they can repeat words and they exhibit echolia
Term
transcortical motor aphasia
Definition
these patients show the same deficits as those shown by patients with brocas aphasia except that they reatin the ability to repeat
Term
Echolalia
Definition
often repeat compulsively
Term
Global aphasia
Definition
neither the ability to comprehend language nor the ability to produce it
Term

N400 ERP compnent

semantics

Definition
when a word either visual or auditory in a sentence violates semantic expectation such as he spread the warm bread with socks
Term

P600 ERP component

syntax

Definition
occurs when the sentence makes no sense semantically but nonetheless has grammatical violation such as the boiled watering can smoke the telephone in the cat
Term
Alexia
Definition
the ability to read during childhood is lost as a consequence of brain damage
Term
Agraphia
Definition
the ability to read during childhood is lost as consequence of brain damage
Term
Double Dissociation
Definition
alexia without agraphia or agraphia with out alexia. the neural control systems for reading and writing are seperable to some extent and do not critically rely on each other
Term
Dual route reading model
Definition
two distinct routes whereby information in visual linguistic format can be linked to meaning
Term

phonological

non lexical

Definition
sounds is mediator in the process of associating print with meaning
Term

phonological

alexia

Definition
disrupted phonological route but an intact direct route. little trouble reading previously learned words (meaning can be extracted directly from the visual form: regular/irregular) disability with reading nonwords or words that are unfamiliar
Term
Deep Alexia
Definition
inability to read nonwords but also show difficulties reading errors in which a word is misread as a word with a related meaning (semantics paralexias) ex forest-> woods
Term

Direct route

lexical

Definition
print is directly associated with meaning without the phonological intermediary. used for irregular words like colonel
Term
Phonological Agraphia
Definition
can manually or orally spell regular and irregular words in dictation but perform poorly with nonwords ex shallice
Term
Lexical agraphia
Definition
reasonable spelling can be produced, both manually and orally, for virtually any regular word or non word but spelling or irregular words are poor
Term
Precentral alexias
Definition
problem arises in the linkage to meaning
Term
peripheral alexias
Definition
inability to process more than one letter at a time to read all the letters in a word or to appreciate the overall form of a group of letters
Term
attentional dyslexia
Definition
can recognize a single letter of a single word in isolation but cant recognize the same letter of a word if it is precented along with items of the same kind.
Term
neglect dsylexia
Definition
consistently misreads the beginning of the end of a word such as misreading discount as mount
Term
spelling dyslexia
Definition
individual letters can be identified but they cant be intergrated to form a word
Term
Memories
Definition
memories are reconstructions not copies
Term

Memory stores

Sensory

Definition

nature of any new memory depends on old information already stored in memory

Where sensory information is kept for a very brief period of time

Term
STM now working memory
Definition
active maintenance of information in short term storage
Term

STM

working memeory

REHEARSAL

Definition
process of keeping information in STM by mentally repeating it
Term

STM

Baddeleys model

Definition

visuospatial sketchpad

visual and spatial matieral: remembering layout, location of a building

Phonological loop: specialized for verbal matiral, lists

Central executive: Controls attention/Integrates information/Manages activities-initiates retrieval from LTM/decision processes

Term

LTM

Encoding

Definition
process of transforming our emotions, perceptions, and thoughts into an enduring (hopeful) memory
Term

LTM

Storage

Definition
process of maintaining information in memory over time
Term

LTM

Retrieval

Definition
process of bringing memories which have been previously encoded and stored into the conciousness mind
Term
Long term potentiation
Definition

connections b/w neurons strengthened by communicating with each other

strengthening lasts for hours or weeks: can last for long time

occurs in several pathways in hippocampus

can be induced rapidly

allows neurons that fire together to wire together

Term
Global nature of amnesia
Definition
global regarding modality (visual, auditory, ect) and material (verbaland non verbal)
Term

what is spared?

WM digit span task

Definition

working memory and skill learning

H.M's ability was normal

7+/-2 (the magic number)

however his performance could not complete extended digit span (one new digit added each time)

normal healthy subjects can do around 20 (using LTM)

Term

Implicit memory (skill learning)-

Mirror tracing task

Definition
allows prior experience to affect behavior without conciously retrieving the memory or even being aware of it
Term

Bilateral, medial temporal lobes+Hippocampus

Type of amnesia:

Deficits:

Definition

antergrade/retrograde amnesia

in learning new information after the onset of amnesia

Term
Antergrade amnesia
Definition
learning new information after the onset of amnesia is impossible
Term
retrograde amnesia
Definition
impairment in memory for information that was acquired priorto event that caused the amnesia
Term
Time line of retrograde amnesia
Definition
extends less than 60 minutes before the injury: can extend back to decades
Term

Retrograde amnesia:

Variablity of severity

Definition
can be temporally or can go back decades
Term
ribots law
Definition
typically there is greater compromise of more recent memories than more remote memories this effect is often referred to as the temporal gradient of retrograde amnesia
Term
episodic semantic
Definition
those autobiographical memories that are specific to our own particular experience that includes context about the time
Term
explicit semantic
Definition
knowledge that allows the formation and retention of facts, concepts, categories, and word meaning and retention of information about ourselves and the people we know such as where they live, their occupations and interests ect
Term
implict semantics
Definition
procedural memory: appears to support memory of how things should be done allowing for the acquistion and expression of skill
Term
Where are LTM stored?
Definition

different aspects of same memory stored in various locations: likely stored in same locations as perceptual process occured

EX: attending a concert: images of band stored in occipital cortex or temporal occipital areas

Term

Hippocampus role

LTM

Definition
associated with memory and relations
Term
basal ganglia and LTM
Definition

those with parkinsons and huntingtons disease show deficits in implicit memory and skill learning

Habit learning

Serial RT task

Term

Amygdala

LTM

Definition

emotional memory

learning of emotional responses: fear conditioning

Damage leads to decreased ability to access information about this internal states

Term
Flashbulb Memories
Definition

detailed recollections of when and where we heard/saw shocking events: 9/11

Not always entirely accurate, but often more so than mundane events

Term

Temporal Lobes

 

Definition

Medial-> episodic

Anterior-> semantic

Term

Hippocampus

consolidation model

Definition
temporal gradient explained
Term

hippocampus

mulitple trace theory

Definition
nature of memory trace shifts to more general forms of memory--> memory becomes more independent of hippocampal system
Term
Hippocampus and retrieval
Definition
different portions of hippocampus involved in encoding vs retrieval
Term
Pattern completion
Definition
reactivation of LTM ie a smell giving rise to visual and auditory items
Term

Prefrontal areas and retrieval

activation levels related to effort required

Definition

posterior: amount of activation correlated to amount of effort required (NOT success of retrieval)

More effort required due to poorer encoding of item-> less effort due to better encoding

Term
LTM working memory
Definition

patients with deficits in working memory can dissociate from having any LTM deficits

Deficits can vary across aspects of working memory: Phonological store

Visuo-spatial sketchpad

Term

LTM working memory

dorsolateral prefrontal cortex

Definition

damage causes impairments in..

even with the smallest delays between presentation of material and task

Human Research: damage causes impairments in more complex manipulation aspects of working memory- more tied with central executive conception

Term

Emotion

Amygdala

Emotional appraisal

Definition

essentially our appsraisal of a situation causes an emotional or affective, response that is going to be based on that appraisal

projects to:

hippocampus and prefrontal areas

hypothalamus and autonomic and hormonal systems

Term
emotional learning
Definition
damage disrupts fear conditioning damage also disrupts reward based learning
Term
fear conditioning
Definition

response and activation to negative stimuli speculated to be greater

likely due to arousal level of negative vs positive stimuli

Term
Fast pathways
Definition

thalamus-> amygdala

immediate fear response

Term
Slow pathways
Definition

thalamus-> cortex->amygdala

more detailed processing

cortex can the instruct amygdala to maintain, increase, or decrease response

Term

Dopaminergic pathways (basal ganglia to midbrain)

Reward and pleasure centers

Definition
specifically pathway from ventral segmental area of midbrain to nucleus accumbens (ventral part of basil ganglia)
Term
Interoperception
Definition
the sens of the phsyiological condition of the body
Term
Insular cortex
Definition

tucked deep inside the sylvian fissure. emphasis is special role in disgust

Disgust: the posterior regions represent primary sensory represtations such as taste and more anterior insular regions integrate these sensations with awareness

Term
anterior cingulate cortex
Definition
attention, selection, motivation, emotion, and pain: emotional saliency
Term
Emotion, motor, cognition interface
Definition

ventral: emotion

dorsal: cognition

Term
orbitofrontal cortex
Definition

is especially important for learning in situations that require the individual to respond to changing patterns of rewards and punishment

 

Term
Evaluation or reward and punishment
Definition

decision making

Damage-> lack of inhibition poor learning from past losses/gains

Term
Emotional regulation
Definition

attempts to manage the emotions that one experiences so that theyre socially appropriate and do not spiral out of control

occurs on a daily basis

some via behavioral mechanisms ex avoiding situations

some via cognitive mechanisms

Term
Increased and decreased activity
Definition

increased: frontal lobes

Decreased- subcortical and posterior areas

Term
reappraisal
Definition

changing emotional experience vis changing meaning of emotional aspects of stimuli

can consciously regulate amygdalas response to emotional stimuli

Term
facial expressions
Definition

ability to recognize and produce is universal

universality hypothesis: emotional expressions have the same meaning for everyon eg everyone understands a smile equals happiness

people are quite accurate at judging emotional expressions of other cultures

people who've never seen the expressions do them naturally

Term
RH and face processing and facial expressions
Definition
right hemisphere specialization for both recognizing and producing facial expressions of emotion. right hemisphere damage particularly to temporal and partial regions of the brain, disrupts the ability to recognize faces much more than does comparable left hemisphere damage
Term
Left bias in expression
Definition
a bias toward showing more the left portion of the face. more expression is expressed on the left side of the face
Term

Capgras syndrome

deficits

Definition

damage to neural connections b/w temporal lobe and limbic system. specifically the facial recognition ares (fusiform face area) and amygdala

typically believe that one or more of their family members and or friends are imposters

no emotional link to face conclude that that person must not be the real one

Term

connection severed b/w amygdala and fusiform face area

prosody

Definition

vocal cues such as pitch or frequency, stress, intensity and timing

affective prosody: communicates the emotional context or tone of an utterance: ex sarcasm

propositional prosody: comminucates lexical or semantic information

Term
aprosodia
Definition
deficits in comprehension of prosody as a result of brain damage, damage associated with the region around the sylvian fissure on the right side of the brain
Term
Motor
Definition
frontal lobe damage, poor production of emotional prosody but intact comprehension
Term
sensory
Definition
temporporiatal damage within intact production of emotional prosody but poor comprehenion
Term
global
Definition
widespread damage to the right hemisphere with deficits in both spontaneous production and comprehenion of prosody
Term
Approach avoidance model
Definition

approach and withdrawal are the two most basic actions and responses to stimuli in enviornment

approach emotions

withdrawal emtions

increased activity in LH frontal regions

increased activity in RH frontal regions

most evidence supported by EEG asymmetrics and correlation to persons disposition at baseline

more optimistic peopel->increas LH frtonal

more pessitimistic people -> increased RH frontal

same trends hold for transient changed in mood

Term
approach vs avoidance emotions
Definition
anger is only real problem can show appraoch or withdrawal behaviors in anger
Term
activation pattern seems to fit w/action taken
Definition

LH approach: more opptimistic or positive outlook

RH avoidance/withdrawal: negative outlooks

pattern of activation in prefrontal areas with depressed patiens

Term
valence arousal model
Definition
arousal or emotional intensity is relfected in activity of posterior sections of the right hemisphere. emotions are best described by two fundamental dimenstions: valence (pleasant vs unpleasant) and arousal (high vs low intensity) frontal regions are asymmetrically involved in the valance aspect of emotion, where as the posterior right hemisphere is involved in the arousal aspect.
Term
Valance: Valance
Definition
pattern of frontal activation; same as approach withdrawal pattern;s higher cognition (such as action)
Term

late positive potential

what does it respond to?

Definition

shows physiological response to high arousing pictures

positive or negative

pleasant and unpleasant pictures

Term
two component theory
Definition
automatic; controlled processing
Term
contention scheduling
Definition
a cognitive system that enables relative atomatic process, which has developed over time through learning a single stimulus may result in a relatively automatic strong of actions referred to as a shcema
Term
supervisory attentional system
Definition
is the cognitive system required to efforfully direct attention and guide action through decision processes, it is active only in certain situation; when no preexisting processing schemsa are available as ocorus in novel situations. the task is technically difficult when problem solving is required and when cretain typical response tendencies much be overridden
Term
evidence from lesion patients
Definition
loss of supervisory attentional system, leaving contention scheduling and routines intact
Term

Perseveration

(no deficits in well learned behaviors)

Definition
the behavior of repeating the same action or thought over and over again
Term
environmental dependency
Definition
actions are impelled or obligated by the phsycial and social enivornment
Term
hierarchical levels of control
Definition

frontal lobes important in regulation of behaviors in non routine situation or when behavior needs to be constrained/inhibited

Lowest-automatic

Middle: executive and supervisory

highest: metacognition and self relfection: the ability to reflect upon a cognitive process

Term
Evidence from lesion patients
Definition

one of the main fxns of frontal lobes is the organization of behavior and controlling non automatice/intentional behaviors

damage to frontal lobes can result in: inability to deal w/novely

lack of cognitive flexibility

inability to guide behavior, self criticize, self monitor

Term
goal directed behaviors
Definition

ability to guide behaviors toward a goal are multifacted

 

Term

Initiating

psychological inertia

Definition

resistance or disinclination to motion, action, or changel. patients with executive dysfuntion are poor at starting an action or a behavior, but once engaged in it they have great difficult stopping it.

Prefrtonal damage

Term

Creating and maintaing

Attentional set

Definition

process that designates which information is relevant to the tast

damage: dorsolateral prefrontal region

Frontal Lobe damage patients wander off task

more activity is observed ind orsolateral prfrontal context when individuals make the selection themselves

frontpolar cortex is involved in multiple tasks

Damage to frontpolar crotex have difficult in managaing sub goals, greater impairment in managment of mulitple goals

Term
Sequencing
Definition
determining what steps to take to attaint the goal and the order or sequence in which those steps must be taken
Term
Self ordered pointing task
Definition
mid dorsolateral prefrontal cortex critical for these types of tasks: individuals are shown array of items, all of which read the same category, shown view number of sheets, sequentially of same items, but in different order
Term
tower of london: dorsolateral prefrontal cortex and frontopolar cortex involved
Definition
used to examine planning and sequencing abilities. requires individual to move the balls at one time from an initial position to a target configuration in a few moves as possible while keeping in mind the constrains impose by the hight of each prong
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