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Physiology Exam 4, Lecture 8
Vestibular System
28
Physiology
Professional
11/10/2011

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Term
Define proprioception
Definition
Conscious and unconscious sense of posture and balance by monitoring head movements
Term
Define motor control
Definition
Adjustment of muscular contraction to maintain posture and balance
Term
Define vestibuloocular reflex
Definition
Adjusting eye movements so that visual target remains on retina in
response to head movements
Term
What is the basic physiological mechanism for balance?
Definition
For the otolith organs and the semicircular canals, movement of the cilia ultimately changes the action potential firing frequency in vestibular neurons by a mechanism similar to that in the cochlea.
Term
What are the otolith organs? What are otoliths?
Definition
The organs are the utricle and saccule, which contain otoliths (crystals of calcium carbonate in gel) that move against cilia.
Term
What do the otolith organs detect?
Definition
Linear acceleration and displacement of the head (e.g., tilting)
Term
Describe cilia depolarization in the otolith organs
Definition
When the head changes its angle, the change in gravity cause otoliths (and the gel surrounding them) to move. This causes cilia movement, which depolarize similarly to in the auditory system

(towards kinocilium= depolarization, away kinocilium=hyperpolarization)
Term
How do just two otolith organs (utricle and saccule) detect any angle tilted by the head?
Definition
The macula in the utricle is arranged in the horizontal axis, and the macula in the saccule is arranged in the vertical axis.
Term
Describe the structure of the semicircular canals.

What is the ampulla, crista, and cupola?
Definition
-Oriented 90 degrees of each other -Filled with endolymph -Has a bulge called the ampulla with a sheet of cells (the crista) that contains cilia -The cilia project into gelatinous mass called the cupola
Term
What do the semicircular canals detect? How?
Definition
Angular acceleration of the head (i.e., sudden turning movements).

The endolymph in the canals exert a force opposite to the rotation due to inertia
Term
If the head rotated to the left, what would happen to the semicircular canal sterocilia?
Definition
In the left horizontal canal, the endolymph would bend cilia towards the kinocilium

In the right horizontal canal, the opposite would occur

(Note: there is always some afferent discharge, even at rest or inhibition)
Term
Why are the horizontal semicircular canals not exactly parallel to the ground?
Definition
Because most of the time when we walk we are looking at the ground, so a 30 degree angle would make more sense
Term
Where are the cell bodies of vestibular bipolar cells?
Definition
In the vestibular (aka Scarpa’s) ganglion, located in the internal auditory meatus
Term
Describe the neural pathway of the vestibular system
Definition
1. Vestibular ganglion
2. Vestibulocochlear nerve (CN VIII)
3. Termination in vestibular nuclei in brainstem
4. Connection with cranial nerve eye muscle nuclei (III, IV, VI)
5. Some ascend to ventral posterial thalamic nucleus
6. Parietal (sensory) and frontal (motor) cortex
Term
How does the lateral rectus (CN VI) move the eye?
Definition
Laterally, toward the ear (abduction)
Term
How does the medial rectus (CN III) move the eye?
Definition
Medially, towards the nose (adduction)
Term
How does the superior rectus (CN III) move the eye?
Definition
It elevates the eye if eye is lateral, it rotates the eye inward if eye is medial
Term
How does the inferior rectus (CN III) move the eye?
Definition
It depresses the eye if eye is later, it rotates the eye outward if eye is medial
Term
How does the superior oblique (CN IV) move the eye?
Definition
It rotates the eye inward (intorsion) if eye is lateral, it depresses the eye if eye is medial
Term
How does the inferior oblique (CN IV) move the eye?
Definition
It rotates the eye outward (extorsion) if eye is lateral, it raises the eye if eye is medial
Term
Define conjugate eye movements
Definition
Eyes move in the same direction.
Term
Define saccades
Definition
Fast movement of the eye from one fixation point to another.

If no saccades, the eye is "staring" and images will disappear because the eye is too used to it
Term
Define smooth pursuit
Definition
Slow movements that track a target across the visual field.
Term
Define nystagmus
Definition
This combination of smooth pursuit movement and saccadic movement. The direction is defined by the rapid movement.

Ordinary, but very common in drunkenness
Term
Define the vestibuloccular reflex
Definition
The reflex that maintains a visual image on the retina during head turning.

It does this by automatically adjusting eye position for the movement of the head.

Thus, if the head turns toward the left, the eyes will move toward the right, due to contralateral excitation/inhibition of eye muscles
Term
Define vertigo
Definition
Illusion of movement, typically spinning
Term
Define Meniere's disease
Definition
Excess endolymph produces excessive force on the hair cells. Result can be deafness, tinnitus, and vertigo.
Term
What often causes motion sickness?
Definition
A mismatch between vestibular signals (eye thinks we're not moving, but vestibular canals say we are)
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