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Physiology Exam 4, Lecture 2
Long Tracks of the CNS
33
Physiology
Professional
10/30/2011

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Term
How many neurons are in a typical somatosensory pathway? Where are they and what are they called?
Definition
3

Primary (sensor cell body), secondary (CNS), tertiary (thalamus)
Term
How many neurons are in a typical motor pathway? What are they called?
Definition
2

Corticospinal, alpha-motor neuron
Term
Define the dorsal column/ medial lemniscal pathway
Definition
The long tract that conveys touch, pressure, vibration, etc from skin to medulla to thalamus
Term
What is the dorsal column that carries information from the lower half of the body called?
Definition
Gracile fasciculus
Term
What is the dorsal column that carries information from the upper half of the body (excluding the face) called?
Definition
Cuneate fasciculus
Term
What secondary neuron would a touch sensory neuron from the lower half of the body terminate upon in the medulla?
Definition
The gracile nucleus
Term
What secondary neuron would a touch sensory neuron from the upper half of the body (excluding the face) terminate upon in the medulla?
Definition
The cuneate nucleus
Term
What is the technical term for a secondary neuron axon "crossing over" to the other side of the medulla before ascending to the thalamus?
Definition
Decussate
Term
What is the name of the thalamic nucleus that receives input from secondary neurons in the dorsal column/ medial lemniscal pathway?
Definition
Ventral posterial lateral (VPL) nucleus

(the tertiary neuron)
Term
Where do tertiary neurons (VPL nucleus) of the dorsal column/ medial lemniscal pathway terminate?
Definition
Cerebral cortex (aka somatosensory cortex) in the "body" region
Term
List the neuron pathway in the dorsal column/ medial lemniscal pathway
Definition
1. Primary afferent neuron
2. Neuron goes up dorsal columns
3. First synapse in medulla on dorsal column nuclei
4. Secondary neurons decussate to opposite side of medulla and ascend to thalamus
5. Termination on VPL nucleus
6. VPL tertiary neurons terminate on somatosensory cortex
Term
What would happen if the dorsal column/ medial lemniscal pathway was damaged?
Definition
Numbness, loss of sensory information
Term
Define the spinothalamic system
Definition
The long tract that conveys pain information from the skin
Term
Describe the primary afferent neuron in the spinothalamic system
Definition
Its cell body is located in the dorsal root ganglion, and after entering the spinal cord it immediately synapses on the secondary neuron
Term
Describe the secondary afferent neuron in the spinothalamic system
Definition
In the spinal cord, they immediately decussate and ascend all the way to the VPL
Term
Where do teriary neurons in the spinothalamic system terminate?
Definition
In the "body" region of the somatosensory cortex
Term
Describe the pathway of the spinothalamic system
Definition
1. Primary afferent neuron enters spinal cord
2. Termination on secondary neuron
3. Secondary axon decussate and ascend to VPL
4. Tertiary neuron terminate in "body" region of the somatosensory cortex
Term
Define the corticospinal tract (aka pyramidal tract)
Definition
Controls voluntary movement, particularly of the fingers and toes
Term
Where is the primary cell body of the corticospinal tract located?
Definition
In the cerebral cortex, in an area called the "primary motor cortex"
Term
Describe the pathway of the primary neuron in the corticospinal tract
Definition
They descend from the primary motor cortex to the lower medulla, where they decussate and continue to the spinal cord, where they terminate on alpha motor neurons
Term
What would damage to the corticospinal tract (aka pyramidal tract) cause?
Definition
Weakness or paralysis
Term
Define lesion
Definition
Any damage to the nervous system, due to stroke, tumor, blunt force trama, CSF, etc
Term
What general area in the lumbal spinal cord are the gracile fasciculus, lateral corticospinal tract, and spinothalamic tract located?

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Definition
[image]
Term
What general area in the cervical spinal cord are the gracile fasciculus, lateral corticospinal tract, cuneate fasciculus, and spinothalamic tract located?

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Definition
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Term
If you were to take slices of the brainstem, where would the midbrain, pons, and medulla be? (rostal, middle, caudal)

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Definition
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Term
What general area in the caudal medulla are the gracile fasciculus, lateral corticospinal tract, cuneate fasciculus, medial lemniscus, and spinothalamic tract located?

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Definition

 

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Term
What general area in the middle medulla are the medial lemniscus, lateral corticospinal tract, and spinothalamic tract located?

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Definition
[image]
Term
What general area in the rostral medulla are the medial lemniscus, lateral corticospinal tract, and spinothalamic tract located?

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Definition
[image]
Term
What general area in the caudal pons are the medial lemniscus, lateral corticospinal tract, and spinothalamic tract located?

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Definition
[image]
Term
What general area in the middle ponsare the medial lemniscus, lateral corticospinal tract, and spinothalamic tract located?

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Definition
[image]
Term
What general area in the rostral pons are the medial lemniscus, lateral corticospinal tract, and spinothalamic tract located?

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Definition
[image]
Term
What general area in the caudal mibrain are the medial lemniscus, lateral corticospinal tract, and spinothalamic tract located?

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Definition
[image]
Term
What general area in the rostal midbrain are the medial lemniscus, lateral corticospinal tract, and spinothalamic tract located?

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Definition
[image]
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