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Physiology Cardio I Month 2 Week 1 Day 1
Physiology Cardio I Month 2 Week 1 Day 1
27
Physiology
Graduate
06/04/2018

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Term
myocardium
Definition
thick muscle layer of heart, pump
Term
functions of pericardium
Definition
fat for energy, fluid in pericardial space to prevent overheating and for lubrication, also coronary blood vessels here
Term
endocardium
Definition
internal surface of the heart, has crenulations/trabeculae carneae and smooth inside surface
Term
cardiac tamponade
Definition
when fluid builds up in the pericardium, making it harder for the heart to pump
Term
thickening of right ventricle indicates
Definition
pulmonary obstruction or problem
Term
lub
Definition
S1, tricuspid and mitral valves closing when ventricles are filled, end of diastole and beginning of systole
Term
dub
Definition
S2, aortic and pulmonary valves close when pressure increases as aorta and pulmonary artery fill, end of systole and beginning of diastole
Term
what controls how much blood gets to a peripheral site?
Definition
arteriole contraction or relaxation, constriction causes resistance to movement
Term
where is there more blood
Definition
in the veins
Term
size of capillaries
Definition
1 blood cell wide, O2 and CO2 get exchanged here
Term
what are hemodynamics
Definition
factors that affect how blood flows out of the heart and through the vessels
Term
positive hydrostatic pressure and neg presssure
Definition
created by the pumping action of the heart, the heart muscle contracts and pushes blood from the ventricles into the blood vessels creating positive pressure which can be measured as BP. negative pressure is also a component when the heart relaxes and ventricles open up again creating negative pressure on the atria so that they begin to fill
Term
resistance and bloodflow
Definition
anything that occludes or obstructs bloodflow. affected by the length and diameter of a blood vessel. as blood vessels get narrower and narrower further from the heart resistance increases.
Term
Poiseuille's Law
Definition
the greater the resistance, the lower the blood flow. halve the diameter and inc resistance 16x
Term
velocity and blood flow
Definition
the distance that blood flows in some period of time
Term
viscosity
Definition
thicker fluids move more slowly, higher hct, extreme hyperglycemia
Term
compliance
Definition
ability of a blood vessel to accommodate some amount of blood volume, large arteries like the aorta are very compliant- can expand to hold more volume. get more noncompliant with age, blood vessels get harder. veins much more compliant than arteries
Term
flow properties from fluid dynamics
Definition
laminar flow- all in one direction, middle moves faster
turbulent flow- blood is hitting something that changes its direction, gurgling. ex atherosclerotic plaque or arteriosclerosis (hardening/thickening of vessel walls)
Term
layers of artery
Definition
epithelial, muscular, outer adventitia
Term
artherosclerosis can cause
Definition
plaque formation w fat deposits that can detach and become a thrombus that can get lodged, inc resistance to flow
Term
arteriosclerosis can cause
Definition
hardening of vessels, occlusion with collagen fiber buildup, dec compliance, turbulence, dec velocity
Term
time spent in systole vs diastole
Definition
shorter time in systole 1/3 (takes longer for ventricles to refill than to empty). 2/3 in diastole
Term
mean arterial pressure
Definition
[systolic + (2 * diastolic) ] / 3
Term
main systemic pressure
Definition
can be 7-10x lower than mean arterial pressure
Term
avg BP of aorta vs capillaries
Definition
100mmHg vs 20
Term
how does blood get pulled back to heart
Definition
negative pressure, vacuum created by venules and venous pressure
Term
why doesn't fluid stay out when it leaves the capillaries?
Definition
it leaves behind proteins and cells while releasing water, salt, glucose and oxygen, leading to an osmotic change wehre the pressure inside the capillary becomes higher than outside, pulling fluid back into the capillary (osmosis is pulling in the interstitial fluid), then there is lower pressure in the venules which pulls fluid into them
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