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| A slender striated strand within skeletal and cardiac muscle fibers and composed of bundles of myofilaments. Myofibrils occur in groups of branching threads running parallel to the cellular long axis of the fiber |
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| The smallest functional unit of a myofibril. Sarcomeres occur as repeating units along the length of a myofibril, occupying the region between Z lines of the myofibril |
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| The protein filaments that construct a myofibrils (Actin and Myosin) |
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| The thin filament of sacromeres. Is coated in Tropomyosin and contains the binding site for the ATPase Head of Myosin |
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| The thick filaments of Sarcomeres. Contains the ATPase head which allows for the muscle contraction. |
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Sarcoplasmic Reticulum
(SR) |
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Definition
| An intracellular membrane network that plays a critical role in the regulation on intracellular Ca2+ concentration |
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| Invaginations of the sarcolemma (plasma membrane) that allow for quick depolarization of the cell |
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| The innervation neurons of skeletal muscle with soma's present within the ventral horn |
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| A motor nerve and all of the muscle fibers innervated by that nerve |
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Definition
(Calcium Release Channel)
The receptors found in the terminal cisternae, are responsible for the elevation in intracellular Ca2+, and bind Ryanodine. |
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(L-type voltage-gated Ca2+ Channel)
Stimulated thru contact with the Ryanodine Receptor of the SR |
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Sarcoplasmic Endoplasmic Reticulum Calcium ATPase
(SERCA) |
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Definition
The pump in thru which Ca2+ is resequestered into the SR.
Most abundant protein in the SR |
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Definition
| The single actin molecules |
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Definition
| The two stranded helical filament formed from g-actin |
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Definition
Protein molecules that cover the binding sites of the actin molecule in the form of a dimers.
The Dimers have a T, I and C subunit. T binds more tropomyosin, I facilitates the inhibition of the binding of myosin, and C binds Ca2+ promoting movement of the troponin dimer to allow binding of Myosin |
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Definition
| Fast glycolitic, fatigue prone, pale fibers |
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| Slow Oxidative, Fatigue resistant, red fibers |
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Definition
| Stimulation of a muscle during which the origin and insertion of the muscle do not move |
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Definition
| Stimulation of a muscle during which the origin and insertion do move |
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| Single-Unit Smooth Muscle |
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Definition
| Smooth muscle cells are electrically coupled so that stimulation of one cell is followed by stimulation of adjacent cells. |
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Definition
| Smooth muscle cells are not electrically coupled, so stimulation of one does not stilumate another adjacent cell |
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