Term
| When it comes to contraction and action and myosin, who pulls who? |
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Definition
| The myosin pulls the actin towards the center of the sarcomere. |
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Term
| What are some key points about thin myofilaments? |
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Definition
| They are made of two intertwined helical strands of G actin globular protein. Troponin C binds calcium. |
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Term
| What are two important sites on thick myofilaments? |
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Definition
| ATP binding site and actin binding site. |
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Term
| Once ATP has undergone partial hydrolysis (to A+M*ADP*Pi), the activated complex is called what? |
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Definition
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Term
| What can be found in the blood following a heart attack? |
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Definition
| Troponin and creatine kinase. The damaged cells are leaky. |
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Term
| What is an isometric contraction? |
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Definition
| When the muscle develops tension but doesn't shorten. It stays the same length. |
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Term
| What ion is important in summation? |
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Definition
| Calcium! More calcium is released from the SR before the muscle can relax completely. |
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Term
| Elongation of the series elastic component of the muscle has what result on the ends of the muscle? |
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Definition
| It delays the tension that the myofilaments at the end of the muscle experience. These cells have tension development that is ATTENUATED and DELAYED. |
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Term
| The elasTic elements include what? |
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Definition
| Titin, Tendons, and connecTive Tissue |
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Term
| What are two positive inotropic agents? What does this mean? |
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Definition
| Epinephrine and norepinephrine (released during exercise) increase active tension in the heart. They do this by increasing calcium current AND calcium uptake by the SR. |
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