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Pharmacotherapy: Infectious Diarrhea
Symptoms vs. Disease and tx
13
Pharmacology
Professional
12/13/2009

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Cards

Term
Vibrio cholerae
Azith 1g x1 once vomiting has ceased
Definition
"rice water stool", dehydration, undercooked food
Term
Shigella
Cipro 500mg BID x5-7d
Definition
bloody diarrhea, fever, from food/people
Term
Etertoxigenic Escherichia Coli
Cipro 750mg x1
Definition
Non-bloody diarhea, nausea, cramps, low grade fever, not meat-related, <24-48hr
Term
Enterhemorrhagic Escherichia Coli
Supportive care only
Definition
Undercooked beef, Bloody diarrhea, hemorraghia, fever, hemolytic uremic syndrome
Term
Clostridium Difficile (w/ stool culture)
Metro 250mg QID x10d
Vanc 125mg QID x10d
Definition
water diarrhea +/- blood, cramps, fever
Term
salmonella (high risk: >50, HIV, valvular disease, prosthesis athero)
bactrim DS bidx5-7d
cipro 500mg bidx5-7d
Definition
eggs, dairy, poultry, F/D +/- V
Term
Campylobacter jejuni
If high fevers, bloody stool, >1wk, preg/HIV
Erythromycin stearate 500mg bid x5d
Definition
raw chicken, patchy destruction of colon walls, RLQ pain
Term
giardia lamblia
tinidazole 2g po x1
nitazoxanide 500mg po BId x3d
metronidazole 250mg po TID x5-7d
Definition
animal feces, bloating, large volume stool, watery/foul smell
Term
Entamoeba histolytica
metro 500-750mg po TID x10d + Paromomycin 500mg PO TID x7d
Definition
tenesmus, small volume w/ mucus, +/- blood
Term
Cryptosporida
self-limiting
HAART to incr. CD4
Definition
day care worker, hiker, swimmer
wt loss, N/V, fever
Term
rotavirus (ORT only)
Definition
children, fecal-oral, 3-9d fever, abd.pain, diarrhea
Term
Norwalk agent (ORT only)
Definition
fecal-oral, raw oysters/clams, N/V/D @1-2d x2-3d
Term
loperamide 4mg po x1, then 2mg po after each loose stool (max 16mg/day)
NOT IF BLOODY
Definition
anti-motility agent
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