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Pharmacology ICD-10 Prep
Pharmacology Review
138
Health Care
Not Applicable
06/30/2012

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Term
Pharmacology
Definition
the study of source, nature, chemistry,preparation, uses and properties of drugs and their effects on living organisms.
Term
Drug
Definition
a substance or biological that can affect the structure or function of the body and is maintained by an official pharmacopoeia or formulary
Term
pharmacopoeia
Definition
a database or compliation describing drugs, chemicals and medicinal preparations maintained by a governing body or organizational body as the American Hospital Formulary Service published by the American Society of Hospital Pharmacists
Term
Codes for medication errors in ICD-10 will be assigned as
Definition
a single combination code, which includes the medication error and external cause of injury
Term
In ICD-10 code, code assignment of medications and their adverse affects will be first found in this list
Definition
Tabular List of ICD-10-CM
Term
What are the two primary routes of drug administration?
Definition
enteral and parenteral
Term
enteral drug administration is
Definition
being or possessing a coating designed to pass through the stomach unaltered and to disintegrate in the intestines
Term
parenteral drug administration is
Definition
situated or occurring outside the intestine
Term
ADME is
Definition
The 4 phases of disposition of drugs within the body.
absorption distribution
metabolism elimination
Term
Receptor is
Definition
a target substance with which drugs interact; a drug may work on more than one receptor
Term
Response is
Definition
the desired and beneficial effect of a drug
Term
Local or Topical effect is
Definition
the drugs effect stays at the site of administration
Term
System effect is
Definition
a drug acts on many sites away from the administration site
Term
Action of drugs is
Definition
where and how a drug combines with tissues
Term
Biotransformation effect is
Definition
if a drug is chemically changed in the body
Term
Toxic side effect is caused by
Definition
more potent drugs which may pose a higher risk of reactions
Term
Tolerance effect occurs when
Definition
the drugs effects diminishes during treatment and increasing amounts are needed to obtain the same effect
Term
Addiction occurs when
Definition
there is a physical and psychological dependence on and craving for a drug
Term
Controlled substances produce
Definition
a tolerance and dependence to the drug and potential for abuse and addition
Term
Addictive Action - 1+1=2 is
Definition
the combination of two similar drugs is equal to the sum of the effects of each, then the drugs are called addictive
Term
Antagonistic - 1+1=0 is
Definition
the drugs have less than an additive effect
Term
Synergistic - 1+1=5 is
Definition
the drugs cause an effect is greater than the sum of the individual effects of the drugs
Term
Syngerism is
Definition
the drugs not only enhance their effect, but greatly enhance or almost multiply the effects of the drugs
Term
Potentiation - a+b=B is
Definition
drug "a" enhances the effect of drug "b" into a capital "B"
Term
Drug toxicity is
Definition
the poisonous and potentially dangerous effects of drugs
Term
Idiosyncrasy is
Definition
an example of an unpredictable type of drug toxicity or any unexpected effect in a patient after drug administration
Term
Anaphylaxis is
Definition
acute hypersensitivity due to a previous exposure
Term
Iatrogenic is
Definition
an effect caused by the treatment and can occur as a result of mistakes or unrecognized individual sensitivity
Term
Adverse reactions are
Definition
harmful, unexpected reactions to drugs
Term
Side effects are
Definition
toxic effects or adverse reactions resulting from drug administration or usage
Term
Contraindications are
Definition
specific situations when the use of a drug is not recommended due to adverse effects
Term
Resistance is
Definition
the lack of beneficial response to a drug
Term
Abuse is
Definition
the use of any drug in a way that deviates from the prescribed dose
Term
Drug abuse is
Definition
excessive or continued use of habit-forming drugs
Term
Absorption is
Definition
Phase 1 of disposition of a drug in the body and is the movement of a drug from the administration site in the blood, i.e. via gut or alimentary canal
Term
Distribution is
Definition
Phase 2 of disposition of a drug in the body and is the transportation of a drug into other body tissues
Term
Metabolism is
Definition
Phase 3 of disposition of a drug in the body and is how well the body breaks down or metabolizes the drug, chemically changes it in the body
Term
Elimination is
Definition
Phase 4 of disposition of a drug in the body and is the elimination of the drug from the body through urine or feces
Term
Potency is
Definition
the drug's strength and is typically used to compare drugs within a class or group that work by the same mechanism
Term
Efficacy is
Definition
the degree to which a drug can produce a certain effect and degree to which a drug is able to induce an effect and is used to compare drugs that have different mechanisms
Term
Absorption is key to
Definition
determining the amount of drug needed, the timing of doses and type of administration
Term
Half life is
Definition
the time the total amount of drug diminishes by one half
Term
Loading dose is
Definition
a large dose given rapidly at the beginning of treatment to reach therapeutic level quickly
Term
Ciprofloxacin should not be taken with
Definition
calcium, magnesium or iron as found in antacids, vitamins or dairy products as this will reduce absorption
Term
Amoxicillin's absorption can be increased when taken with
Definition
antacids
Term
When drugs enter the bloodstream, the first organ encountered is the
Definition
liver
Term
Most drugs bind to ________ in the bloodstream and the drugs are no longer floating free and maybe unable to cross membranes to produce the intended effect
Definition
proteins
Term
Obesity and diseses that cause fluid retention can cause
Definition
a change in drug distribution
Term
To many drugs in the bloodstream at once may complete to bind with proteins causing a
Definition
drug interaction
Term
Metabolism changes or transforms drugs to make them inactive or into molecules for easy __________ from the body
Definition
elimination
Term
Administration of inactive drugs become active after _______________ inside the body.
Definition
metabolism or change takes place
Term
Liver and kidney function decrease with age which results in
Definition
a slow down of drug metabolism and elimination
Term
Prozac is safe/useful in young healthy adults, but may not the best choice for older adults on multiple medications as Prozac will _________
Definition
possible slow down the metabolism of many of drugs used to treat chronic conditions is older adults.
Term
This food can also slow down metabolism of medications.
Definition
Grapefruit juice
Term
What herbal supplement can speed up drug metabolism?
Definition
St Johns wort
Term
Analgesics, Anesthetics, Antibiotics, Antiviral, Anticoagulants, Antiplatelets, Anticonvulsants, Antidepressants, Anti-Alzheimer, Antidiabetics, Antihistimines, Anti-osteoporosis and SERM are names of __________
Definition
Classes of Drugs
Term
Tylenol, hydrocodone, aspirin, ibuprofen and naproxen are in this class of drug
Definition
Analgesics
Term
Nitrous oxide, penthothal, lidocaine and procaine are in this class of drugs
Definition
Anesthetics
Term
Lotrimin and Monistat are antifungals assigned to this class of drugs
Definition
Antibiotics
Term
Rifadin, Isoniazid and ethambutol are antitubercular and assigned to this class of drugs
Definition
Antibiotics
Term
Ceftin is a cephalosporin and assigned to this class of drugs
Definition
Antibiotics
Term
Amoxicillin is a penicillin and assigned to this class of drugs
Definition
Antibiotics
Term
Biaxin is one of the Erythromycins and assigned to this class of drugs
Definition
Antibiotics
Term
Ciprofloxacin, Levaquin are Quinolones assigned to this class of drugs
Definition
Antiobiotics
Term
Bactrim is a sulfa drug or a sulfonamides assigned to this class of drugs
Definition
Antibiotics
Term
Doxcycline is one of the Tetracyclines assigned to this class of drugs
Definition
Antibiotics
Term
Chemical substances that fight bacterial infections are classifed as ___________
Definition
Antibiotics
Term
The class of drugs called Antibiotics include 8 subclasses of drugs. Name them.
Definition
Antifungal, Antitubercular, Cephalosporins, Erythromycins, Penicilllins, Quinolones, Sulfonamides/Sulfa, Tetracyclines
Term
Antiviral drugs are relatively recent drugs used to __________________
Definition
prevent infection or shorten the duration of infections by preventing the virus from spreading, although it may not kill viruses that already exist
Term
Name the antiviral drug used to treat chickenpox and symptoms of herpes infections of the skin, eyes, mouth, genitals or brain
Definition
Acyclovir
Term
Name the virus that will stay dormant in the body an can cause symptoms again in the future.
Definition
Herpes simplex virus
Term
Name the antiviral drug used to treat and prevent Influenza A
Definition
Amantadine
Term
Name the two antiviral drugs sometimes prescribed for adults who develop chronic hepatitis.
Definition
Ribavirin and Interferon
Term
Name two anticoagulants (blood thinners) which prevent clotting or coagulatoin of blood
Definition
Coumadin (warfarin) and Lovenox (heparin)
Term
Name the most common antiplatelet medication which reduces the tendency of platelets to stick together.
Definition
Aspirin
Term
Name one anticonvulsant which is used alone or in combination with other meds to control certain types of seizures. This drug is also used to treat trigeminal neuralgia.
Definition
Tegretol (Carbamazepine)
Term
Name two antidepressant drugs
Definition
Paxil, Zoloft
Term
Name the anti-Alzheimer drug
Definition
Aricept (donepezil)
Term
Name the types of antidiabetic insulins
Definition
rapid acting
short acting
intermediate acting
long acting
Term
Precose (acarbose) is what type of antidiabetic drug
Definition
oral
Term
Name the class of drugs for Zytrec, Benadryl, Allegra and Claratin
Definition
Antihistamines
Term
Name the class of drugs for Bisphosphonates-alendronate (fosamax)
Definition
Anti-osteoporosis
Term
Tamoxifen (Nolvadex) is assigned to this class of drugs
Definition
SERM - Selective Estrogen Receptor Nodulator
Term
Name two Digitalis preparations prescribed to increase the force of the heart's contractions and beneficial in heart failure and irregular heartbeats.
Definition
Digoxin and Digitoxin (Lanoxin)
Term
Name the class of cardiovascular drug which dilates the blood vessels
Definition
ACE inhibitors
Term
Name the class of cardiovascular drugs which prevent angiotensin from reacting on receptors in the blood vessels in patients who cannot tolerate ACE inhibitors.
Definition
ARBs
Angiotensin 2 Receptor Antagonists
AT-2
Term
Name the commonly prescribed ARBs Angiotensin 2 Receptor Blockers
Definition
Candesartan (Atacand)
Eprosartan (Teveten)
Irbesartan (Avapro)
Losartan (Cozaar)
Telmisartan (Micardis)
Valsartan (Diovan)
Term
Name the class of cardiovascular drugs which decrease muscular tone in blood vessels leading to vasodilation.
Definition
Beta Blockers (Beta-Adrenergic Blocking Agents)
Term
Beta Blockers are prescribed to treat the following diseases
Definition
Angina, hypertension, arrhythmias and heart attack
Term
Acebutolol (Sectral), Atenolol (Tenormin), Nadolol (Corgard) Sotalol (Betapace) are assigned to this class of drugs ___________________
Definition
Beta Blockers
Term
Name the class of cardiovascular drugs which dilate blood vessels, lower blood pressure and treat angina and arrhythmia.
Definition
Calcium Channel Blockers (Calcium Antagonists or Calcium Blockers)
Term
Calcium Channel Blockers are prescribed to treat the following diseases
Definition
angina, arrhythmia, hypertension, atrial fibrillation, migraines and Raynaud's syndrome
Term
Amlodipine (Norvasc, Lotrel), Diltiazem (Cardizem, Tiazac), Nifedipine (Adalat, Procardia) Verapamil (Calan, Isoptin, Verelen are in this class of cardiovascular drugs
Definition
Calcium Channel Blockers
Term
Name two cholesterol binding drugs
Definition
Questran or Colestid
Term
Name the common types of cholesterol lowering drugs
Definition
statins, resins, niacin (nicotinic acid, gemfibrozil and clofibrate
Term
A statin is the most common form of this drug
Definition
antihyperlipidemic
Term
Diuretics are also known as water pills. Name the most commonly prescribed diuretics
Definition
Bumetanide (Bumex) Chlorothiazide (Diuril), Furosemide (Lasix), Spironolactone (Aldactone)
Term
Antihypertensive drugs are
Definition
beta blockers, calcium channel blockers and diuretics
Term
Name the class of endocrine drug for male hormone replacement
Definition
Androgens
Term
Name the class of endocrine drug that interferes with androgens and are used in prostate cancer
Definition
Antiandrogens
Term
Name the class of endocrine drug which reduces the amount of estrogen in the blood and are effective against breast cancer
Definition
Aromatase inhibitors
Term
Name the class of endocrine drug which replaces female hormones
Definition
Estrogens
Term
Name the class of endocrine drug which produces estrogen like effects on bone
Definition
SERM
Selective estrogen receptor modulator
Term
Name the class of endrocrine drug which is used to treat abnormal uterine bleeding
Definition
Progestins
Term
Name the class of endocrine drug used to treat hypothyroidism
Definition
Thyroid Hormone
Term
Name the class of endocrine drug used in treatment of osteoporosis
Definition
PTH
Parathyroid Hormone
Term
Name the class of endocrine drug used for treatment of acromegaly
Definition
Growth Hormone Release Inhibiting Factor
Somastatin
Term
Name the class of GI drugs which neutralize hydrochloric symptoms / reduce
Definition
Antacids
Term
Name the class of GI drug that are acid reducing
Definition
H2 Blockers
Term
Name of H2 blockers
Definition
Tagamet, Pepcid, Axid, Zantac
Term
Name antacids
Definition
Rolaids, Tums, Prilosec OTC, Maalox
Term
Name the GI class of drug that relieves diarrhea
Definition
Antidiarrheals
Term
Name the class of GI drugs that relieve nausea
Definition
Antinauseants
Term
Name the class of GI drugs that treat autoimmune disease as Crohn's
Definition
Anti TNF (tumor necrosis factor)
Term
Name a prescribed antidiarrheal drug
Definition
Lomotil
Term
Name an antinauseant drug
Definition
Reglan
Term
Name the class of GI drugs that stop production of acid
Definition
Antiulcer and Anti GERD
Term
Name the most commonly prescribed or OTC GI drugs that stop acid production
Definition
Tagamet, Nexium, Pepcid, Prevacid and Prilosec
Term
Name the class of GI drugs that relieve constipation
Definition
Cathartics
Term
Name commonly prescribed GI drugs that relieves constipation
Definition
Colace and Peri
Term
Bronchodilators, Leukotriene Modifiers, Steroid inhalers and IV or Oral Steroids are classified to this type of drug
Definition
Respiratory Drugs
Term
Albuterol (Proventil), Maxair, Alupent are assigned to this class of Respiratory drugs
Definition
Bronchodilators
Term
Zyflo (zileuton) is assigned to this class of respiratory drugs
Definition
Leukotriene Modifiers
Term
AeroBid, Azmacort (triamcinolone) are assigned to this class of respiratory drugs
Definition
Steroid inhalers
Term
Decadron, Medrol and prednisone are assigned to this class of respiratory drugs
Definition
Steroids IV or Oral
Term
Halcion (triazolam), Restoril (temazepam) and Luminal (phenobarbital) are assigned to this class of drugs
Definition
Sedative-Hypnotics
Term
Caffeine and Ritalin (methylphenidate) are assigned to this class of drugs
Definition
Stimulants
Term
Alprazolam (Xanax), Lorazepam (Ativan) and Diazepam (Valium) are considered to be minor medications in this class of drugs
Definition
Tranquilizers - Minor
Term
Haloperidol, Loxapine and Pimozide are considered to be major medications which reduce confusion and are in this class of drugs
Definition
Tranquilizers - Major
Antipsychotics or neuroleptic
Term
Oral Antidiabetic drugs are
Definition
gliizide / Glucotrol XL
metformin / Glucophage
proglitazone / Actos
acarbose / Precose
Term
The six main areas of pharmacology are
Definition
Pharmaceuticals, medicinal chemistry, pharmacokinetics, chemotherapy, toxicology, pharmacodynamics and molecular
Term
The chemical name of a drug specifies the chemical make up of the drug. The generic name is derived from the chemical and usually starts with a
Definition
lower case letter
Term
The chemical name of a drug specifies the chemical make up of the drug. The brand name is the property and registered brand name usually starts with
Definition
Capital letter
Term
The six routes of drug administration are
Definition
Oral, sublingual, rectal, parenteral, inhalation, topical application
Term
Name the type of drugs used in cancer therapy which blocks specific enzymes & growth factor receptors involved in cancer cell proliferation
Definition
signal transduction inhibitors
Term
This type of cancer therapy regulates gene expression and other cellular functions
Definition
It modifies the function of proteins
Term
This cancer therapy induces cancer cells to die and is called
Definition
apoptosis
Term
This cancer therapy blocks the growth of blood vessels to tumors and is called
Definition
angiogenesis
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