Term
|
Definition
50 + (2.3 x Height in Inches over 60)
45 + (2.3 x Height in Inches over 60) |
|
|
Term
|
Definition
| ABW=IBW + 0.4 (TBW – IBW) |
|
|
Term
|
Definition
| square root of ht(cm)x Wt(kg)/3,600 |
|
|
Term
| what equation is used to calculate the CrCl ml/min? |
|
Definition
Cockcroft-Gault equation
(140-age)(Wt Kg)/(72)(SrCr mg/dl) |
|
|
Term
| What are the normal values for CrCl in men and women |
|
Definition
Normal CrCl
97-137 ml/min males
88-128 ml/min females
Renal dysfunction
<60ml/min |
|
|
Term
| What is the normal creatinine levels in men and women |
|
Definition
| Normal creatinine in men 0.8 to 1.3 mg/dl and in women: 0.6 to 1.0 mg/dl. |
|
|
Term
| What is the Volume of Distribution equation |
|
Definition
|
|
Term
| The elimination rate constant equation |
|
Definition
|
|
Term
|
Definition
t ½ hr= 0.693/Kd
Or
t ½ hr= (0.693)(Vd)/Cl |
|
|
Term
| What is the SS Steady State? |
|
Definition
| Point at which, after multiple doses, amount of drug administered over a dosing interval equals amount of drug being eliminated over that same period |
|
|
Term
| Which body weight should you use to calculate CrCl |
|
Definition
| IBW unless the person is OBESE, then use the adjusted body weight |
|
|
Term
| what's the criteria for being obese |
|
Definition
| if your actual body weight is 20% greater than your IBW |
|
|
Term
| What can you say about a drug that has a high Vd(L) |
|
Definition
|
|
Term
| What can you say about a drug that has a low Vd(L) |
|
Definition
|
|
Term
| if you double the dose and the concentration doubles, what order drug is it? |
|
Definition
|
|
Term
|
Definition
| The fraction of the drug eliminated is constant |
|
|
Term
| Describe Zero order drugs |
|
Definition
| The AMOUNT of Drug eliminated over time is constant |
|
|
Term
| What is CrCl and indicator of? |
|
Definition
| of how well your kidneys are working |
|
|
