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| knowledge of the history, source, physical, and chemical properties, compounding, biochemical and physiological effects mechanisms of action, absorption, distribution biotransformation and excretion and therapeutic and other uses of drugs |
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| deals with absorption, distribution, biotransformation and excretion of drugs |
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| study of the physiological effects and the mechanisms of action |
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| aspects of pharmacology that deal with the adverse effects of drugs |
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| any chemical agent that affects living processes; primarily interested in drugs that are useful in the prevention, diagnosis and treatment of human disease or in the prevention of pregnancy |
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| drugs that bind to receptors and mimic the body's own regulatory molecules |
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| produce their effects by preventing endogenous substances from activating a receptor. if there is no agonist, present antagonists have no effect. |
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| moderate intrinsic action, not full action, can either increase or decrease effect. |
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| drug that produces usual effect at unexpectedly low doses |
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| drug produces its effects only at unusually large doses |
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| hyporeactivity acquired as the result of prior exposure to the drug |
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| combined action of drugs which is greater than the effects of each used alone |
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| actions other than the intended therapeutic effects resulting from the pharmacological action of a drug |
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| interference of one drug with the effect of another drug, nutrient, or potentiate which will increase/decrease the therapeutic/adverse effects. |
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| name given to a drug once it is ready to be marketed, usually easier to remember than its chemical name (Ex: Toothpaste) |
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registered name at the patent office by company which registered the drug and approved by the FDA; each company markets the drug under its own trade name; patent rights expire after 17 years, other companies can market the drug under its generic name or the company's brand name. (Ex: Colgate) |
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| drug subject to strict laws defining how it is prescribed, distributed, and stored |
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| time required for the body to reduce drug concentration to 1/2. (Most drugs removed in 5 half-lifes) |
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| amount of drug necessary to maintain the physiological status quo steady state. |
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| drug given absorbed through oral or gi tract mucosa |
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| given other than through gi tract, has come to mean IV, IM, or SC |
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| into the subvutaneous tissue |
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| inert substance given to a person for its suggestive effects, to please a person |
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