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Pharmacology
Psych
10
Medical
Graduate
03/12/2006

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Cards

Term
Typical Antipsychotics
Definition
Haloperidol(Haldol®)
Phenothiazines:
  • Thioridazine [piperidine]
  • Fluphenazine [piperizine]
  • Chlorpromazine (Thorazine®) [aliphatic]
  • Term
    Typical Antipsychotics MoA
    Definition
    D2 Receptor blocker
    Term
    High potency
    Typical Antipsychotic SEs
    Definition
    "Parkinsonian-like" symptoms:
    Extrapyramidal system SE's
    Akathesia
    Acute dystonia
    Tarditive dyskinesia
    Term
    Atypical Antipsychotics
    Definition
    Clozapine
    Risperidone
    Olanzapine (Zyprexa®)
    Quetiapine (Seroquel®)
    Ziprasidone
    Aripiprazole (Abilify®)
  • (partial DA agonist)
  • Term
    Atypical Antipsychotic MoA
    Definition
    D2 receptor antagonism, coupled with 5-HT2A receptor antagonism
    Term
    Selective Seratonin Reuptake Inhibitors
    (SSRIs)
    Definition
  • citalopram
  • escitalopram
  • fluoxetine
  • paroxetine (Paxil®)
  • sertraline
  • Term
    Low potency
    Typical Antipsychotic SEs
    Definition
    Weight gain (H1)
    Anticholinergic (M1)
    Orthostais (α1)
    OD →neuroleptic malignant syndrome
    Term
    Tricyclic Antidepressants
    (TCAs)
    Definition
  • # amitriptyline (Elavil®, Endep® Tryptanol®))
  • desipramine (Norpramin®, Pertofrane®)
  • imipramine (Tofranil®)
  • Term
    Mood-stabilizing Drugs
    Definition
  • Valproic acid/Valproate (Depakene®,Depakote®)
  • Lithium
  • Gabapentin (Neurontin®)
  • Term
    TCA Side Effects
    Definition
  • Antihisaminergic (sedation)
  • Anticholinergic (constipation)
  • Antiadrenergic (orthosatic hT)
  • Increased cardiac conduction,
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