| Term 
 
        | Drug used for hypertensive emergency |  | Definition 
 
        | Vasodilators; Minoxidil (loniten), diazoxide (hyperstat IV), sodium nitroprusside (Nitropress). Vasodilators decrease the workload of the heart. Can dilate the arterioles and/or veins |  | 
        |  | 
        
        | Term 
 
        | PT ed with nitroglycerin (organic, stable/variant angina, vasodilator)
 |  | Definition 
 
        | Do not withdraw abruptly, S/S of orthostatic HTN, HA (when applying ointment-wear gloves), tachycardia, flushing, dizziness, rash w/patches |  | 
        |  | 
        
        | Term 
 
        | Assessments with pt on diuretics |  | Definition 
 
        | monitor BP, diet high in potassium, monitor fluids (retention), S/S dehydration, potassium supplements, orthostatic HTN, thirst is SE, take with meals, report wght gain/loss, monitor I&O |  | 
        |  | 
        
        | Term 
 
        | Pharmacologic goals for treatment of angina |  | Definition 
 
        | Prevent MI or death and anginal pain |  | 
        |  | 
        
        | Term 
 
        | Pt ed for pts taking antidysrhythmics drugs |  | Definition 
 
        | Patient skilled in taking pulse, recognize health status changes, reduce CV risk factors, avoid alcohol, common SE-diarrhea, med ID tag |  | 
        |  | 
        
        | Term 
 
        | Beta-blockers and pts with COPD Beta-blocker-DOC---Propranolol
 |  | Definition 
 
        | Causes bronchospasms (inderal)-should be used caution |  | 
        |  | 
        
        | Term 
 
        | Lab tests for heparin and coumadin |  | Definition 
 
        | Heparin-PTT (Partial thrombosplastin time) 20- 30sec
 Coumadin-PT (Prothrombin time) 12-15sec
 INR (International normalized ratio) 2.5
 |  | 
        |  | 
        
        | Term 
 
        | Antidotes for heparin and coumadin |  | Definition 
 
        | Vitamin K/protamine sulfate |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Suppresses coagulation by helping antithrombin inactivate clotting factors-thrombin & factor Xa. Administer by injection only |  | 
        |  | 
        
        | Term 
 
        | Process for changing pt from heparin to coumadin |  | Definition 
 
        | Never just stop heparin; start coumadin while weaning off heparin |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Warfarin-an oral anticoagulant-prevention Heparin-911 onset
 |  | 
        |  | 
        
        | Term 
 
        | Uses for Ticlid (Ticlopidine) Antiplatelet Drug
 |  | Definition 
 
        | Prevention of thrombotic stroke |  | 
        |  | 
        
        | Term 
 
        | When best to give a tissue plasminogen activator (time frame) uses: MI, ischemic stroke or PE |  | Definition 
 
        | Not given if pain present for more than 12hrs; best if given within 4-6 hours; guidelines suggest w/i 30min. Accelerated: Front-loaded schedule; scheduled infusion time is 90 minutes compared to 3 hours in the past
 |  | 
        |  | 
        
        | Term 
 
        | Drug for pain/HA etc if taking coumadin |  | Definition 
 
        | NO NSAIDS Take Tylenol-Acetaminophen
 |  | 
        |  | 
        
        | Term 
 
        | MOA of ASA First Generation NSAIDS
 |  | Definition 
 
        | Nonselective inhibitor of cyclooxygenase; Reductions in pain & inflammation-inhibiting COX2 Protection against MI and ischemic stroke-inhibiting COX1
 |  | 
        |  | 
        
        | Term 
 
        | MOA of epoetin alfa-growth factor-erythrocytes (RBCs) |  | Definition 
 
        | produced by recombinant DNA technology; protein is identical to human erythropoietin-a natural hormone. Stimulates bone growth |  | 
        |  | 
        
        | Term 
 
        | Assessment with pt taking digoxin (also) when to give and not give |  | Definition 
 
        | Monitor pulse (full minute) prior to administration; hold medication if pulse is <60-call Dr. |  | 
        |  | 
        
        | Term 
 
        | Pt teaching with ACE inhibitors---esp with orthstatic hypotension |  | Definition 
 
        | Low blood pressure=orthostatic hypotension, especially with elderly-fall risk. SE=cough |  | 
        |  | 
        
        | Term 
 
        | Pt ed with cholesterol lowering drugs---esp with how to increase HDL |  | Definition 
 
        | Diet/exercise is first line of therapy - best way to increase HDL. Statins have greatest impact when given daily at night. Have patient limit cholesterol and saturated fat. |  | 
        |  | 
        
        | Term 
 
        | SE of nitroglycerin---causes of headache |  | Definition 
 
        | Wear gloves when applying ointment; dosing may be too high |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Profound effect of the electrical and mechanical properties of the heart; increase mycardio contractility, which increases blood to the kidneys-which increases urine, increases CO |  | 
        |  | 
        
        | Term 
 
        | Major obstacles to successful chemotherapy |  | Definition 
 
        | Death of healthy cells, cure=100% kill, absence of early detection, solid tumors respond poor, drug resistance, limited drug access to tumor cells |  | 
        |  | 
        
        | Term 
 
        | Why used of Allopurinol in chemotherapy |  | Definition 
 
        | increases amounts of uric acid-hyperuricimia that develops secondary to cancer chemo-cells dye=breakdown of DNA releases uric acid-administer before starting chemo |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Myopathy; rhabdomyolysis...S/S unexplained muscle pain/stiffness |  | 
        |  | 
        
        | Term 
 
        | When pt should take a diuretic  (MOA) |  | Definition 
 
        | Take early in the morning to minimize nocturia, when taken 2x p/d; take at 8am and 2pm; restrict K-rich food-nuts, dried fruit, spinach, citrus fruit, potatoe or bananas |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | stress diet unless on K sparing diuretic, monitor BP, pulse, weight, take med immediately if missed. Signs of dehydration, id tag |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Blocks Na+ and chloride reabsorption |  | 
        |  | 
        
        | Term 
 
        | Assessment with Pt taking diuretics |  | Definition 
 
        | BP, pulse, dehyd, weight, |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | tx diarrhea, reduce fluid vol/discharge from ileostomy. Allow fluid absorption. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Neutralize acids and prevent the conversion of pepsinogen to pepsin in the stomach; react with gastric acid to produce neutral salts or salts of low acidity; enhance mucosal protection by stimulating production of prostoglandins |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Constipation and diarrhea |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Promote healing by suppressing secretions of gastric acid; decrease amount of acid in stomach |  | 
        |  | 
        
        | Term 
 
        | Goal of antineoplastic therapy |  | Definition 
 
        | decrease size of neoplasms so immune system can deal with it, may include cure, decrease tumor size, relieve symptoms, kill metastisis cells, prolong life. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | N/V, diarrhea, toxicty, neutropenia, thrombocytopenia, bone marrow suppression, anemia |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Suppressing secretions of gastric acid, PPIs (protein pump inhibitor) most effective drug Goals: eleviate complications/symptoms,  heal, prevent complication and reccurrence
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Stimulate intestinal motility, increase amount of water and electrolytes in the intestinal lumen; used for opioid induced constipation/constipation from slow intestinal transit |  | 
        |  | 
        
        | Term 
 
        | Nsg interventions of stomatitis assoc with chemo |  | Definition 
 
        | include oral hygiene, bland diet, topical oral antifungal drugs for infection. Mild: mouthwash with topical antisthetic and antifunal, severe case: use of opiods. |  | 
        |  | 
        
        | Term 
 
        | Why combination chemotherapy |  | Definition 
 
        | Drug combo benefit, suppression of drug resistance, increased cancer kill (different cycles of the cell), reduction of injury to health cells. Growth fraction of the cells |  | 
        |  | 
        
        | Term 
 
        | Meaning of cell cycle specific in chemotherapy |  | Definition 
 
        | Cells have phases, -when specific, only toxic to cells that are in a particular growth phase-must be in blood for a long period of time |  | 
        |  | 
        
        | Term 
 
        | Type of laxative for pt lacking fiber in the diet |  | Definition 
 
        | Bulk-forming; functions like dietary fiber-swell with H2o to form a gel to soften the fecal mass and increase the mass. METAMUCIL |  | 
        |  | 
        
        | Term 
 
        | SE of 1st generation antihistamines |  | Definition 
 
        | Drowsiness/sedative (Benedryl) |  | 
        |  | 
        
        | Term 
 
        | When not to give antihistamines |  | Definition 
 
        | Pregnant or lactating women; monitor elderly and children |  | 
        |  | 
        
        | Term 
 
        | ASA and Pt having surgery ASA Promotes bleeding inhibits platelet aggregation
 |  | Definition 
 
        | For surgeries where lots of bleeding is possible, discontinue high doses of aspirin one week prior to procedure. For low-bleeding risk surgeries (dental); there is no reason to discontinue aspirin therapy. |  | 
        |  | 
        
        | Term 
 
        | SE of COX-2 inhibitors (major) |  | Definition 
 
        | Cardiovascular risks; MI & stroke.  Dyspepsia, abd pain, renal toxicity. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Osteoarthritis, rheumatoid arthritis, acute pain, dysmenorrhea, familial ademonatous polyposis |  | 
        |  | 
        
        | Term 
 
        | Pt Assessment and pts taking glucocorticoids Suppress immune response/prevent rejection
 |  | Definition 
 
        | Increased risk for infection, thinning of skin, bone dissolution with fx, impaired growth in children, suppression of hypothalamic-pituitary-adrenal axis |  | 
        |  | 
        
        | Term 
 
        | How to take pts off of steroids |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Who should not be taking high dose steroids |  | Definition 
 
        | Ptnts with systemic fungal infections; receiving live virus vaccines, pediatric patients & pregnancy/breast-feeding |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Give patient antigen and hope they develop antibodies |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | AVOID grapefruit juice-increases response; more likely to experience SE |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | nephrotoxicity, infection, HTN, sinusitis, hyperkalemia, anaphylactic reactions |  | 
        |  | 
        
        | Term 
 
        | Med for children prior to getting immunizations |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | Hypoglycemia; must eat w/i 30minutes of taking |  | 
        |  | 
        
        | Term 
 
        | Reason for tight control of BG in DM |  | Definition 
 
        | To achieve primary goal-prevent long-term complications; reduction in microvascular complications; greatly reduces mortality and morbidity |  | 
        |  | 
        
        | Term 
 
        | Reason to rotate injection sites with insulin admin |  | Definition 
 
        | minimize adverse local reactions; formation of hollows or depressions in the skin "orange peel" |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | promote cellular glucose uptake and metabolism |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | hepatic and renal function tests, blood glucose levels, vit b12 and folic acid levels |  | 
        |  | 
        
        | Term 
 
        | Beta blockers and hypoglycemia |  | Definition 
 
        | Drug interaction/block the bodies interpretation of hypoglycemia.  Increase effects of insulin. |  | 
        |  | 
        
        | Term 
 
        | Type of insulin used for IV admin |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | Benefit of using long acting glargine insulin |  | Definition 
 
        | provides basal level of insulin throughout the night and the following day; provides tight glucose control. levels steady over 24 hrs. reduce hypoglycemia. |  | 
        |  | 
        
        | Term 
 
        | When to check BS level when switching from insulin to an oral hypoglycemic drug |  | Definition 
 
        | more frequently, additional teaching needed |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | rx w/gastrica acid to produce neutral salts/salts w/ low acidity, decrease destruction of gut wall, enhance mucosal protection stimulating production of prostaglandins, prevent the conversion of pepsinogen to pepsin in stomach |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | constipation or diarrhea, caution in renal impaired pt., may prevent the absorption of other meds, can cause retention of K |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Decrease  amt of acid in the stomach, want to use up the H so pt doesn't make more HCL, promote healing by suppressing secretions of gastric acid |  | 
        |  | 
        
        | Term 
 
        | CHF treatment goals relief of symptoms...... |  | Definition 
 
        | slowing HR, increasing contractility, reducing cardiac workload |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Stimulates bone marrow to produce red blood ells |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | TX of chemo induced neutropenia |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | Decrease neutropenia and risk of infection |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Increase number of leukocytes |  | 
        |  | 
        
        | Term 
 
        | Patient teaching storage for Insulin |  | Definition 
 
        | do not freeze, keep in fridge, after opening-good for one month, keep out of direct sunlight and extreme heat |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | decreases appetite, inhibits glucose production in liver; reduces glucose absorption slightly in gut |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | drowsiness, red/dry skin, fruity breath, anorexia, abdominal pain, N/V, dry mouth, increased urination, rapid-deep breathing, thirsty, weight loss |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Increased anxiety, blurred vision, chilly, cold sweating, pallor, confusion, difficulty concentrating, drowsiness, HA, nausea, increased pulse, shakiness, increased weakness, increased appetite |  | 
        |  | 
        
        | Term 
 
        | Nursing Teaching-insulin has which drug effect? |  | Definition 
 
        | Enhances carbohydrate metabolism |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MONA B Morphine, O2, Nitroglycerin, Aspirin, Beta Blockers
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | MONA B Morphine, O2, Nitroglycerin, aspirin, beta blockers
 |  | 
        |  |